A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect Nancy J. MillenbaughM. Guillaume WientjesJessie L.-S. Au ORIGINAL ARTICLE Pages: 265 - 272
Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles Pek Yee LumLeock Y. NgoJashvant D. Unadkat ORIGINAL ARTICLE Pages: 273 - 278
Phase I/II study of cisplatin, ifosfamide and irinotecan with rhG-CSF support in patients with stage IIIB and IV non-small-cell lung cancer Akihisa FujitaHirotsugu TakabatakeKyuhichiro Sekine ORIGINAL ARTICLE Pages: 279 - 283
Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours Huw D. ThomasMichael J. LindAlan V. Boddy ORIGINAL ARTICLE Pages: 284 - 290
Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients Johannes SchüllerJim CassidyBruno Reigner ORIGINAL ARTICLE Pages: 291 - 297
N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE), a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs Lorne J. BrandesGary M. QueenFrank S. LaBella ORIGINAL ARTICLE Pages: 298 - 304
Effect of high-dose cyclosporine on etoposide pharmacodynamics in a trial to reverse P-glycoprotein (MDR1 gene) mediated drug resistance Bert L. LumSonja KaubischBranimir I. Sikic ORIGINAL ARTICLE Pages: 305 - 311
Ara-C affects formation of cancer cell DNA synthesome replication intermediates Waleed Abdel-AzizHai-Yan JiangLinda H. Malkas ORIGINAL ARTICLE Pages: 312 - 319
Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome Hai Yan JiangRobert J. HickeyLinda H. Malkas ORIGINAL ARTICLE Pages: 320 - 328
Comparison of the protective effects of amifostine and dexrazoxane against the toxicity of doxorubicin in spontaneously hypertensive rats Eugene H. HermanJun ZhangVictor J. Ferrans ORIGINAL ARTICLE Pages: 329 - 334
Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide James L. FlowersSusan M. LudemanDavid J. Adams ORIGINAL ARTICLE Pages: 335 - 344
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts Henry S. FriedmanRobert C. CastellinoDarell D. Bigner ORIGINAL ARTICLE Pages: 345 - 349