Determination of flavopiridol (L86 8275; NSC 649890) in human plasma by reversed-phase liquid chromatography with electrochemical detection Sherman F. StinsonKimberly HillTracy W. Daw ORIGINAL ARTICLE Pages: 261 - 265
Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia receiving 6-thioguanine versus 6-mercaptopurine Norbert ErbDörthe O. HarmsGritta Janka-Schaub ORIGINAL ARTICLE Pages: 266 - 272
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin Theodor W. SchulteLeonard M. Neckers ORIGINAL ARTICLE Pages: 273 - 279
Inhibition of intestinal microflora β-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats Kiyoshi TakasunaTakehiro HagiwaraTetsuya Kamataki ORIGINAL ARTICLE Pages: 280 - 286
Prevention of apomorphine- or cisplatin-induced emesis in the dog by a combination of methylnaltrexone and morphine Joseph F. FossChun-Su YuanLeon I. Goldberg ORIGINAL ARTICLE Pages: 287 - 291
Fluorescence methods to assess multidrug resistance in individual cells Eric J. NelsonNoah T. ZinkinPatricia M. Hinkle ORIGINAL ARTICLE Pages: 292 - 299
Pharmacokinetics, antifolate activity and tissue distribution of PT523 in SCC VII tumor-bearing mice Joel E. WrightMario PardoAndre Rosowsky ORIGINAL ARTICLE Pages: 300 - 306
Prediction of carboplatin clearance calculated by patient characteristics or 24-hour creatinine clearance: a comparison of the performance of three formulae Hiroaki OkamotoAkira NagatomoKoshiro Watanabe ORIGINAL ARTICLE Pages: 307 - 312
A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice F. M. SirotnakJ. I. DeGrawJ. R. Piper ORIGINAL ARTICLE Pages: 313 - 318
Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines Francesca CivoliLarry W. Daniel ORIGINAL ARTICLE Pages: 319 - 326
Sequence effect of irinotecan (CPT-11) and topoisomerase II inhibitors in vivo Joseph Paul EderVictor ChanBeverly A. Teicher ORIGINAL ARTICLE Pages: 327 - 335
Advanced colorectal cancer in the elderly: results of consecutive trials with 5-fluorouracil-based chemotherapy Silvana ChiaraMaria Teresa NobileRiccardo Rosso CLINICAL TRIAL REPORT Pages: 336 - 340
Superiority of hepatic arterial infusion in preventing catabolism of 5-FU compared with portal vein infusion revealed by an in vivo 19F NMR study Kiyotaka OkunoNorihiko HiraiMasayuki Yasutomi SHORT COMMUNICATION Pages: 341 - 344