1. Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors

   • T. S. Garimella
   • D. D. Ross
   • K. S. Bauer

   Original Article 01 October 2004 Pages: 101 - 109

   

2. P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats

   • Amrita V. Kamath
   • Saeho Chong
   • Punit H. Marathe

   Original Article 27 August 2004 Pages: 110 - 116

   

3. Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours

   • P. M. J. McSheehy
   • R. E. Port
   • J. R. Griffiths

   Original Article 05 October 2004 Pages: 117 - 128

   

4. Lack of strain-related differences in drug metabolism and efflux transporter characteristics between CD-1 and athymic nude mice

   • Marcella Martignoni
   • Ruben de Kanter
   • Mario Monshouwer

   Original Article 22 September 2004 Pages: 129 - 135

   

5. A phase I and pharmacologic study of the matrix metalloproteinase inhibitor CP-471,358 in patients with advanced solid tumors

   • André Planting
   • Ate van der Gaast
   • Jaap Verweij

   Original Article 29 September 2004 Pages: 136 - 142

   

6. Comparative preclinical toxicology and pharmacology of isophosphoramide mustard, the active metabolite of ifosfamide

   • N. Germann
   • S. Urien
   • Lee Roy Morgan

   Original Article 14 September 2004 Pages: 143 - 151

   

7. Alternating weekly administration of paclitaxel and gemcitabine: a phase II study in patients with advanced non-small-cell lung cancer

   • David Aguiar
   • José Aguiar
   • Uriel Bohn

   Original Article 22 September 2004 Pages: 152 - 158

   

8. Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model

   • Jun Chen
   • Huimin Lin
   • Ming Hu

   Original Article 29 September 2004 Pages: 159 - 169

   

9. Tissue distribution of arsenic species in rabbits after single and multiple parenteral administration of arsenic trioxide: tissue accumulation and the reversibility after washout are tissue-selective

   • Chun-Jung Lin
   • Mei-Hwan Wu
   • Ann-Lii Cheng

   Original Article 21 August 2004 Pages: 170 - 178

   

10. Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine

    • Jing Jin
    • Feng-Peng Wang
    • Gengtao Liu

    Original Article 16 September 2004 Pages: 179 - 188

    

11. Synergistic antitumor activity of TRAIL combined with chemotherapeutic agents in A549 cell lines in vitro and in vivo

    • Qing-Lin Fan
    • Wen-Yi Zou
    • Wei Wei

    Original Article 29 July 2004 Pages: 189 - 196

    

12. Phase II study of a fixed dose-rate infusion of gemcitabine associated with docetaxel in advanced non-small-cell lung carcinoma

    • J. De Castro
    • A. Lorenzo
    • Oncopaz Cooperative Group

    Original Article 21 August 2004 Pages: 197 - 202