1. Doxorubicin-induced apoptosis in caspase-8-deficient neuroblastoma cells is mediated through direct action on mitochondria

   • Abdelhadi Rebbaa
   • Pauline M. Chou
   • Bernard L. Mirkin

   Original Article Pages: 423 - 428

2. The experimental neuroprotectant leukaemia inhibitory factor (LIF) does not compromise antitumour activity of paclitaxel, cisplatin and carboplatin

   • Frances M. Boyle
   • Cecilie Beatson
   • John B. Kurek

   Original Article Pages: 429 - 434

3. Stereospecific antitumor activity of radicicol oxime derivatives

   • Shiro Soga
   • Sreenath V. Sharma
   • Shiro Akinaga

   Original Article Pages: 435 - 445

4. Phase I study of second-line chemotherapy with docetaxel and carboplatin in advanced non-small-cell lung cancer

   • Mikio Oka
   • Minoru Fukuda
   • Shigeru Kohno

   Original Article Pages: 446 - 450

5. 8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs

   • Susan K. Robbins
   • Susan Houlbrook
   • Adrian L. Harris

   Original Article Pages: 451 - 458

6. A comparison of limited sampling strategies for prediction of Ecteinascidin 743 clearance when administered as a 24-h infusion

   • Charlotte van Kesteren
   • R. Mathôt
   • J. Beijnen

   Original Article Pages: 459 - 466

7. Phase I clinical and pharmacokinetic trial of irofulven

   • James P. Thomas
   • Rhoda Arzoomanian
   • Howard Bailey

   Original Article Pages: 467 - 472

8. Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in murine Lewis lung carcinoma and human Calu-6 non-small-cell lung carcinoma xenografts

   • Beverly A. Teicher
   • Krishna Menon
   • Margaret M. Faul

   Original Article Pages: 473 - 480

9. Phase I/II and pharmacologic study of irinotecan and carboplatin for patients with lung cancer

   • Mitsuo Sato
   • Masahiko Ando
   • Yoshinori Hasegawa

   Original Article Pages: 481 - 487

10. Gemcitabine activity in cervical cancer cell lines

    • Patricia Hernández
    • Primitivo Olivera
    • Jorge Meléndez-Zajgla

    Original Article Pages: 488 - 492

11. Phase I trial of capecitabine in combination with interferon alpha in patients with metastatic renal cancer: toxicity and pharmacokinetics

    • David Z. Chang
    • Thomas Olencki
    • Ronald Bukowski

    Original Article Pages: 493 - 498

12. A phase II study of paclitaxel plus cisplatin for advanced non-small-cell lung cancer in Japanese patients

    • Hiroshi Sakai
    • Shuichi Yoneda
    • Nagahiro Saijo

    Clinical Trial Report Pages: 499 - 503