1. The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

   • Long G. Wang
   • Xiao M. Liu
   • Daniel R. Budman

   REVIEW Pages: 355 - 361

2. Modulation of apoptosis and enhancement of chemosensitivity by decreasing cellular thiols in a mouse B-cell lymphoma cell line that overexpresses bcl-2

   • Michael D. Story
   • Raymond E. Meyn

   ORIGINAL ARTICLE Pages: 362 - 366

3. Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs

   • Michael D. Story
   • Nena Mirkovic
   • Raymond E. Meyn

   ORIGINAL ARTICLE Pages: 367 - 371

4. A phase I evaluation of multitargeted antifolate (MTA, LY231514), administered every 21 days, utilizing the modified continual reassessment method for dose escalation

   • David A. Rinaldi
   • John G. Kuhn
   • Daniel D. Von Hoff

   ORIGINAL ARTICLE Pages: 372 - 380

5. Schedule-dependent interactions between paclitaxel and etoposide in human carcinoma cell lines in vitro

   • Yasuhiko Kano
   • Miyuki Akutsu
   • Saburo Tsunoda

   ORIGINAL ARTICLE Pages: 381 - 388

6. Effect of gastric pH on the relative oral bioavailability and pharmacokinetics of temozolomide

   • Philip Beale
   • Ian Judson
   • Michael Brada

   ORIGINAL ARTICLE Pages: 389 - 394

7. Toxicity of dolastatin 10 in mice, rats and dogs and its clinical relevance

   • Jon C. Mirsalis
   • Janice Schindler-Horvat
   • Charles A. Tyson

   ORIGINAL ARTICLE Pages: 395 - 402

8. Phase I clinical and pharmacological study of oral methoxymorpholinyl doxorubicin (PNU 152243)

   • Cristiana Sessa
   • Massimo Zucchetti
   • Franco Cavalli

   ORIGINAL ARTICLE Pages: 403 - 410

9. Antiangiogenic potential of camptothecin and topotecan

   • Mark K. Clements
   • Carleton B. Jones
   • Sayed S. Daoud

   ORIGINAL ARTICLE Pages: 411 - 416

10. Clinical study of an organic arsenical, melarsoprol, in patients with advanced leukemia

    • Steven L. Soignet
    • William P. Tong
    • Raymond P. Warrell Jr.

    ORIGINAL ARTICLE Pages: 417 - 421

11. Pharmacokinetics and metabolism of doxorubicin after short-term infusions in lymphoma patients

    • Anders Andersen
    • Harald Holte
    • Lars Slørdal

    ORIGINAL ARTICLE Pages: 422 - 426

12. Glutamyl hydrolase and the multitargeted antifolate LY231514

    • Myung S. Rhee
    • Thomas J. Ryan
    • John Galivan

    ORIGINAL ARTICLE Pages: 427 - 432

13. Favorable therapeutic index of a p210BCR-ABL-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors

    • Bernd Kasper
    • Stefan Fruehauf
    • W. Jens Zeller

    ORIGINAL ARTICLE Pages: 433 - 438