1. Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cisplatin encapsulated in long-circulating, pegylated liposomes (SPI-077) in tumor-bearing mice

   • Mary S. Newman
   • Gail T. Colbern
   • Michael A. Amantea

   ORIGINAL ARTICLE Pages: 1 - 7

2. Epirubicin-containing high-dose chemotherapy followed by autologous hematopoietic progenitor cell transfusion for patients with chemotherapy-sensitive metastatic breast cancer: results of 5-year follow-up

   • Yoshinori Ito
   • Taketo Mukaiyama
   • Noboru Horikoshi

   ORIGINAL ARTICLE Pages: 8 - 12

3. Inhibition of paclitaxel elimination in the isolated perfused rat liver by Cremophor EL

   • A. G. Ellis
   • L. K. Webster

   ORIGINAL ARTICLE Pages: 13 - 18

4. In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance

   • Jian Feng Ma
   • Geraldine Grant
   • Peter W. Melera

   ORIGINAL ARTICLE Pages: 19 - 28

5. Effect of Tween-80 on cell killing by etoposide in human lung adenocarcinoma cells

   • Ichiro Tsujino
   • Tetsuo Yamazaki
   • Takashi Horie

   ORIGINAL ARTICLE Pages: 29 - 34

6. Pharmacokinetics of melphalan in isolated limb perfusion

   • A. Norda
   • U. Loos
   • W. Hohenberger

   ORIGINAL ARTICLE Pages: 35 - 42

7. The p53 tumor suppressor gene in anticancer agent-induced apoptosis and chemosensitivity of human gastrointestinal cancer cell lines

   • Manabu Yamamoto
   • Yoshihiko Maehara
   • Keizo Sugimachi

   ORIGINAL ARTICLE Pages: 43 - 49

8. Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice

   • Ming Liu
   • Matthew S. Bryant
   • W. Robert Bishop

   ORIGINAL ARTICLE Pages: 50 - 58

9. Use of V79 cells with stably transfected cytochrome P450 cDNAs in studying the metabolism and effects of cytotoxic drugs

   • Philip Agop Philip
   • Shadan Ali-Sadat
   • Kenneth K. Chan

   ORIGINAL ARTICLE Pages: 59 - 67

10. Inability to escalate vinorelbine dose intensity using a daily × 3 schedule with and without filgrastim in patients with metastatic breast cancer

    • Kathleen A. Havlin
    • Michael J. Ramirez
    • Eric P. Winer

    ORIGINAL ARTICLE Pages: 68 - 72

11. Multiple DNA repair mechanisms and alkylator resistance in the human medulloblastoma cell line D-283 Med (4-HCR)

    • Qing Dong
    • Stewart P. Johnson
    • Henry S. Friedman

    ORIGINAL ARTICLE Pages: 73 - 79

12. Modulation of cyclophosphamide activity by O 6-alkylguanine-DNA alkyltransferase

    • Henry S. Friedman
    • Anthony E. Pegg
    • O. Michael Colvin

    ORIGINAL ARTICLE Pages: 80 - 85

13. Phase II study of mitoxantrone by 14-day continuous infusion with granulocyte colony-stimulating factor (GCSF) support in patients with metastatic breast cancer and limited prior therapy

    • Lajos Pusztai
    • Frankie A. Holmes
    • Gabriel N. Hortobagyi

    ORIGINAL ARTICLE Pages: 86 - 91

14. Pharmacokinetics of paclitaxel in an anephric patient

    • Michael H. Woo
    • David Gregornik
    • Mary V. Relling

    SHORT COMMUNICATION Pages: 92 - 96