1. A lymphoma cell line resistant to 4-piperidinopiperidine was less sensitive to CPT-11

   • Y. Onishi
   • Masao Oguro
   • Harutoshi Kizaki

   ORIGINAL ARTICLE Pages: 473 - 478

2. Response of sensitive and resistant IgM immunocytomas to cis-diamminedichloroplatinum(II) does not correlate with the platination level or with the formation or removal of DNA adducts

   • Cornelis P. J. Vendrik
   • Anne Marie J. Fichtinger-Schepman
   • P. A. Steerenberg

   ORIGINAL ARTICLE Pages: 479 - 485

3. Preclinical antitumor activity of water-soluble paclitaxel derivatives

   • William C. Rose
   • John L. Clark
   • Anna Maria Casazza

   ORIGINAL ARTICLE Pages: 486 - 492

4. In vitro phase II comparison of the cytotoxicity of a novel platinum analog, nedaplatin (254-S), with that of cisplatin and carboplatin against fresh, human ovarian cancers

   • David S. Alberts
   • Paul T. Fanta
   • Sydney E. Salmon

   ORIGINAL ARTICLE Pages: 493 - 497

5. Isolation and structural confirmation of N-desmethyl topotecan, a metabolite of topotecan

   • H. Rosing
   • V. M. M. Herben
   • J. H. Beijnen

   ORIGINAL ARTICLE Pages: 498 - 504

6. Age-related pharmacokinetics of daunorubicin and daunorubicinol following intravenous bolus daunorubicin administration in the rat

   • B. J. Cusack
   • Stephan P. Young
   • Richard D. Olson

   ORIGINAL ARTICLE Pages: 505 - 512

7. Tissue distribution of transdermal toremifene

   • L. Soe
   • Gregory T. Wurz
   • M. W. DeGregorio

   ORIGINAL ARTICLE Pages: 513 - 520

8. Cell cycle effects of antifolate antimetabolites: implications for cytotoxicity and cytostasis

   • John L. Tonkinson
   • Philip Marder
   • L. G. Mendelsohn

   ORIGINAL ARTICLE Pages: 521 - 531

9. Preclinical pharmacokinetics of β-L-dioxolane-cytidine, a novel anticancer agent, in rats

   • Laura E. Moore
   • F. D. Boudinot
   • Chung K. Chu

   ORIGINAL ARTICLE Pages: 532 - 536

10. Adrenal proteins bound by a reactive intermediate of mitotane

    • W. Cai
    • Raymond E. Counsell
    • Linda L. Wotring

    ORIGINAL ARTICLE Pages: 537 - 540

11. Mechanisms of enhancement of the antitumour activity of melphalan by the tumour-blood-flow inhibitor 5,6-dimethylxanthenone-4-acetic acid

    • Frederik B. Pruijn
    • M. van Daalen
    • W. R. Wilson

    ORIGINAL ARTICLE Pages: 541 - 546

12. High-dose toremifene in advanced renal-cell carcinoma

    • Michael M. Gershanovich
    • Vladimir M. Moiseyenko
    • Markku Anttila

    CLINICAL TRIAL REPORT Pages: 547 - 551

13. Interference by antifolate drugs in a folate competitive protein-binding assay

    • Anthea Hardcastle
    • Stephen Clarke
    • W. Aherne

    SHORT COMMUNICATION Pages: 552 - 553

14. Pharmacokinetics and tissue distribution of idarubicin and its active metabolite idarubicinol in the rabbit

    • M. Looby
    • R. Linke
    • M. Weiss

    SHORT COMMUNICATION Pages: 554 - 556

15. Plasma concentrations of polysorbate 80 measured in patients following administration of docetaxel or etoposide

    • L. K. Webster
    • Martha E. Linsenmeyer
    • Michael J. Millward

    SHORT COMMUNICATION Pages: 557 - 560

16. Effect of ifosfamide on intracellular glutathione levels in peripheral blood lymphocytes and its correlation with therapeutic response in patients with advanced ovarian cancer

    • I. A. Malik
    • Naseema Mehboobali
    • M. Perwaiz Iqbal

    SHORT COMMUNICATION Pages: 561 - 565