1. Penetration of etoposide into human malignant brain tumors after intravenous and oral administration

   • Katsuzo Kiya
   • Tohru Uozumi
   • Kaoru Kurisu

   Original Articles Pages: 339 - 342

2. Relations between the penetration, binding and average concentration of cytostatic drugs in human tumour spheroids

   • Martin Erlanson
   • Erika Daniel-Szolgay
   • Jörgen Carlsson

   Original Articles Pages: 343 - 353

3. A phase I and pharmacokinetic study of 12-h infusion of flavone acetic acid

   • Ian N. Olver
   • Lorraine K. Webster
   • Kerrie H. Stokes

   Original Articles Pages: 354 - 360

4. Ionic rhenocene derivatives with antitumor activity

   • P. Köpf-Maier
   • T. Klapötke

   Original Articles Pages: 361 - 366

5. Relationship between the cellular accumulation and the cytotoxicity of S12363, a new vinca alkaloid derivative

   • Alain Pierré
   • Valérie Pérez
   • Ghanem Atassi

   Original Articles Pages: 367 - 374

6. A phase I and pharmacology study of GR63178A, a water-soluble analogue of mitoquidone

   • Diana M. Eccles
   • Jeffrey Cummings
   • John F. Smyth

   Original Articles Pages: 375 - 378

7. Pharmacokinetics and toxicity of the antitumour agentN-[2-(dimethylamino)ethyl]acridine-4-carboxamide after i.v. administration in the mouse

   • James W. Paxton
   • Deborah Young
   • Eain M. Cornford

   Original Articles Pages: 379 - 384

8. Influence of glutathione administration on the disposition of free and total platinum in patients after administration of cisplatin

   • R. Leone
   • M. E. Fracasso
   • A. Bernareggi

   Original Articles Pages: 385 - 390

9. Variability in the pharmacokinetics of epirubicin: a population analysis

   • Janet R. Wade
   • Andrew W. Kelman
   • Brian Whiting

   Original Articles Pages: 391 - 395

10. Treatment of cancer patients with a low-density-lipoprotein delivery vehicle containing a cytotoxic drug

    • Danuta Filipowska
    • Tomasz Filipowski
    • Anthony Breeze

    Original Articles Pages: 396 - 400

11. Treatment of inoperable hepatocellular carcinoma by intra-arterial Lipiodol and 4′-epidoxorubicin

    • W. T. Leung
    • W. C. T. Shiu
    • C. Metreweli

    Short Communication Pages: 401 - 404

12. Intestinal obstruction due to diffuse peritoneal fibrosis at 2 years after the successful treatment of malignant peritoneal mesothelioma with intraperitoneal mitoxantrone

    • L. Thomas Vlasveld
    • Babs G. Taal
    • Sjoerd Rodenhuis

    Short Communication Pages: 405 - 408

13. Phase II study of ACNU as second-line treatment in small-cell lung cancer

    • A. S. Th. Planting
    • T. A. W. Splinter
    • EORTC Lung Cancer Cooperative Group

    Short Communication Pages: 409 - 411

14. Acknowledgement to reviewers

    Acknowledgments Pages: 412 - 412