Articles

1. Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer

   • Yadong Wang
   • Zhicheng Huang
   • Naixin Liang

   Research Open access 26 April 2024 Article: 111

   

2. Interleukin 33 supports squamous cell carcinoma growth via a dual effect on tumour proliferation, migration and invasion, and T cell activation

   • Graziela Perri
   • Vanessa Garcia Vilas Boas
   • Ana Paula Campanelli

   Research Open access 25 April 2024 Article: 110

   

3. Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study

   • Sara Maher
   • Hesham A. Elmeligy
   • Manal Kamel

   Research Open access 25 April 2024 Article: 109

   

4. A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis

   • Qingyang Lei
   • Shanshan Zhen
   • Yi Zhang

   Research Open access 20 April 2024 Article: 108

   

5. A phase I trial of autologous RAK cell immunotherapy in metastatic renal cell carcinoma

   • Jing Xu
   • Wen Zhang
   • Jie Ma

   Research Open access 20 April 2024 Article: 107

   

6. Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study

   • Francesco Massari
   • Matteo Santoni
   • Joaquim Bellmunt

   Research Open access 18 April 2024 Article: 106

   

7. Correction to: Dominant‑negative transforming growth factor‑β receptor‑armoured mesothelin‑targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer

   • Ke Li
   • Jing Xu
   • Yu Kang

   Correction Open access 18 April 2024 Article: 105

8. Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell acute lymphoblastic leukemia

   • Sha Ma
   • Ying Wang
   • Kailin Xu

   Research Open access 17 April 2024 Article: 104

   

9. Intratumor injection of BCG Ag85A high-affinity peptides enhanced anti-tumor efficacy in PPD-positive melanoma

   • Lanqun Qin
   • Guiying Zhang
   • Zhengyun Zou

   Research Open access 17 April 2024 Article: 103

   

10. TLR5 agonist in combination with anti-PD-1 treatment enhances anti-tumor effect through M1/M2 macrophage polarization shift and CD8⁺ T cell priming

    • Junseok Lee
    • Keon-Il Im
    • Seok-Goo Cho

    Research Open access 17 April 2024 Article: 102

    

11. Expansion of tumor-infiltrating lymphocytes from head and neck squamous cell carcinoma to assess the potential of adoptive cell therapy

    • Sangjoon Choi
    • Mofazzal Hossain
    • Hee Jin Lee

    Research Open access 17 April 2024 Article: 101

    

12. Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma

    • Sophia Stock
    • Luisa Fertig
    • Sebastian Kobold

    Research Open access 17 April 2024 Article: 100

    

13. T-cell subsets and cytokines are indicative of neoadjuvant chemoimmunotherapy responses in NSCLC

    • Ling Yi
    • Ziwei Xu
    • Yi Han

    Research Open access 15 April 2024 Article: 99

    

14. Incorporating IL7 receptor alpha signaling in the endodomain of B7H3-targeting chimeric antigen receptor T cells mediates antitumor activity in glioblastoma

    • Nithidol Sakunrangsit
    • Nattarika Khuisangeam
    • Supannikar Tawinwung

    Research Open access 15 April 2024 Article: 98

    

15. Integrating bulk and single-cell sequencing data to construct a Scissor⁺ dendritic cells prognostic model for predicting prognosis and immune responses in ESCC

    • Maosheng Cheng
    • Jianqi Xiong
    • Shuang Chen

    Research Open access 15 April 2024 Article: 97

    

16. CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival

    • Jessica Wedig
    • Shrina Jasani
    • Thomas A. Mace

    Research Open access 15 April 2024 Article: 96

    

17. Dual-loss of PBRM1 and RAD51 identifies hyper-sensitive subset patients to immunotherapy in clear cell renal cell carcinoma

    • Ziyang Xu
    • Wenbin Jiang
    • Jiejie Xu

    Research Open access 12 April 2024 Article: 95

    

18. Bifidobacterium modulation of tumor immunotherapy and its mechanism

    • Bo Pei
    • Shixuan Peng
    • Fuxiang Zhou

    Review Open access 02 April 2024 Article: 94

    

19. The prognostic and potentially immunomodulatory role of cartilage oligomeric matrix protein in patients with gastric and esophageal adenocarcinoma

    • Konstantinos S. Papadakos
    • Gilar Gorji-Bahri
    • Anna M. Blom

    Research Open access 02 April 2024 Article: 93

    

20. Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy

    • Jhen-Yu Chen
    • Po-Yu Lin
    • Kevin Chih-Yang Huang

    Research Open access 02 April 2024 Article: 92

    

21. circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis

    • Qingtao Liu
    • Pei Xu
    • Fangbao Ding

    Research Open access 30 March 2024 Article: 91

    

22. IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models

    • Justin Yu
    • Jacob Gadwa
    • Sana D. Karam

    Research Open access 30 March 2024 Article: 90

    

23. Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours

    • Manish R. Patel
    • Melissa Johnson
    • Lillian L. Siu

    Research Open access 30 March 2024 Article: 89

    

24. Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression

    • Jingbo Ma
    • Jian Tan
    • Keqiang Liu

    Research Open access 30 March 2024 Article: 88

    

25. The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy

    • Wenxin Lu
    • Guangyu Wu
    • Liwei Wang

    Research Open access 30 March 2024 Article: 87

    

26. SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue

    • Kelly J. Gregory
    • Holly Mason
    • Sallie S. Schneider

    Brief Report Open access 30 March 2024 Article: 86

    

27. TGF-β1 and TGF-βR1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation

    • Zihao Niu
    • Peng Sun
    • Guojun Li

    Research Open access 30 March 2024 Article: 85

    

28. IL-2 promotes expansion and intratumoral accumulation of tumor infiltrating dendritic cells in pancreatic cancer

    • Tingting Gong
    • Xinyang Huang
    • Qi Wang

    Research Open access 30 March 2024 Article: 84

    

29. 23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling

    • Zeping Fan
    • Yaru Cui
    • Wenbin Duan

    Research Open access 30 March 2024 Article: 83

    

30. DR30318, a novel tri-specific T cell engager for Claudin 18.2 positive cancers immunotherapy

    • Zhe Ma
    • Zhenxing Zhou
    • Lushan Yu

    Research Open access 30 March 2024 Article: 82

    

31. Characterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models

    • Hongyu Xue
    • Zhimin Zhang
    • Kai Chen

    Research Open access 30 March 2024 Article: 81

    

32. Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth

    • Andrew N. Wilkinson
    • Rui Chen
    • Sherry Y. Wu

    Research Open access 30 March 2024 Article: 80

    

33. Efficacy of immune checkpoint inhibitors differs in various status of carcinoma: a study based on 29 cohorts with 3255 participants

    • Chunlan Wu
    • Yujun Ke
    • Xianhe Xie

    Research Open access 30 March 2024 Article: 79

    

34. Lipid droplets-related Perilipin-3: potential immune checkpoint and oncogene in oral squamous cell carcinoma

    • Yijia He
    • Lingyun Liu
    • Liang Ding

    Research Open access 30 March 2024 Article: 78

    

35. Targeting osteosarcoma with canine B7-H3 CAR T cells and impact of CXCR2 Co-expression on functional activity

    • Jennifer W. Cao
    • Jessica Lake
    • Steven Dow

    Research Open access 30 March 2024 Article: 77

    

36. PGRN inhibits CD8⁺T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM

    • Ting Zhou
    • Husun Qian
    • Bianqin Guo

    Research Open access 30 March 2024 Article: 76

    

37. Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer

    • Kaiqi Zhang
    • Yuan Xu
    • Kai Yin

    Research Open access 27 March 2024 Article: 75

    

38. Clinical evidence for efficacy of pembrolizumab in MSI-H and TMB-H advanced solid tumor: results from three cancer centers in China

    • Huan Yan
    • Lianxi Song
    • Liang Zeng

    Research Open access 07 March 2024 Article: 74

    

39. Oct4 activates IL-17A to orchestrate M2 macrophage polarization and cervical cancer metastasis

    • Zhuoqiong Bian
    • Xiaoling Wu
    • Yidong Wang

    Research Open access 02 March 2024 Article: 73

    

40. A phase 2 study of AZD4635 in combination with durvalumab or oleclumab in patients with metastatic castration-resistant prostate cancer

    • Gerald S. Falchook
    • James Reeves
    • Emerson Lim

    Research Open access 02 March 2024 Article: 72

    

41. Molecular classification reveals the sensitivity of lung adenocarcinoma to radiotherapy and immunotherapy: multi-omics clustering based on similarity network fusion

    • Jianguo Zhang
    • Yangyi Li
    • Conghua Xie

    Research Open access 02 March 2024 Article: 71

    

42. Outcomes in biomarker-selected subgroups from the KESTREL study of durvalumab and tremelimumab in recurrent or metastatic head and neck squamous cell carcinoma

    • Tanguy Y. Seiwert
    • Sophie Wildsmith
    • Amanda Psyrri

    Research Open access 02 March 2024 Article: 70

    

43. Construction of an immune predictive model and identification of TRIP6 as a prognostic marker and therapeutic target of CRC by integration of single-cell and bulk RNA-seq data

    • Wenjun Liu
    • Xitu Luo
    • Hao Liu

    Research Open access 02 March 2024 Article: 69

    

44. Size selection of intrahepatic lesions for cryoablation contributes to abscopal effect and long-term survival in patients with liver metastatic melanoma receiving PD-1 blockade therapy

    • Lujun Shen
    • Hongtong Tan
    • Weijun Fan

    Research Open access 02 March 2024 Article: 68

    

45. Neutrophils seeking new neighbors: radiotherapy affects the cellular framework and the spatial organization in a murine breast cancer model

    • C. M. Reichardt
    • M. Muñoz-Becerra
    • L. E. Muñoz

    Research Open access 02 March 2024 Article: 67

    

46. Integrating molecular subtype and CD8⁺ T cells infiltration to predict treatment response and survival in muscle-invasive bladder cancer

    • Bingyu Li
    • Kaifeng Jin
    • Weijuan Zhang

    Research Open access 02 March 2024 Article: 66

    

47. Combination of IL-33 with PD-1 blockade augment mILC2s-mediated anti-tumor immunity

    • Jiawei Yue
    • Hui Guo
    • Yumin Wu

    Research Open access 02 March 2024 Article: 65

    

48. Clinical immunotherapy in pancreatic cancer

    • Xiaorong Ye
    • Yue Yu
    • Hongdi Ma

    Review Open access 02 March 2024 Article: 64

    

49. Riboflavin-LSD1 axis participates in the in vivo tumor-associated macrophage morphology in human colorectal liver metastases

    • Cristiana Soldani
    • Giulia De Simone
    • Laura Brunelli

    Research Open access 02 March 2024 Article: 63

    

50. Mechanism exploration of Zoledronic acid combined with PD-1 in the treatment of hepatocellular carcinoma

    • Xinru Fan
    • Zijun Yan
    • Hui Wang

    Research Open access 02 March 2024 Article: 62