Articles

1. Camrelizumab plus famitinib in previously chemo-immunotherapy treated patients with advanced NSCLC: results from an open-label multicenter phase 2 basket study

   • Shengxiang Ren
   • Anwen Xiong
   • Caicun Zhou

   Research Open access 10 May 2024 Article: 124

   

2. Single-cell sequencing of tumour infiltrating T cells efficiently identifies tumour-specific T cell receptors based on the T cell activation score

   • Chaoting Zhang
   • Shance Li
   • Zheming Lu

   Brief Report Open access 10 May 2024 Article: 123

   

3. Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma

   • Xin Wu
   • Tao Mi
   • Dawei He

   Research Open access 07 May 2024 Article: 122

   

4. Integrative analysis of single-cell and bulk RNA sequencing unveils a machine learning-based pan-cancer major histocompatibility complex-related signature for predicting immunotherapy efficacy

   • Jia-Lin Feng
   • Bo Liang
   • Jun Chen

   Research Open access 07 May 2024 Article: 121

   

5. Chemoradiotherapy versus surgery after neoadjuvant chemoimmunotherapy in patients with stage III NSCLC: a real-world multicenter retrospective study

   • Song Guan
   • Jifeng Sun
   • Lujun Zhao

   Research Open access 07 May 2024 Article: 120

   

6. Efficacy and safety of surufatinib plus toripalimab, a chemotherapy-free regimen, in patients with advanced gastric/gastroesophageal junction adenocarcinoma, esophageal squamous cell carcinoma, or biliary tract cancer

   • Panpan Zhang
   • Zhendong Chen
   • Lin Shen

   Research Open access 07 May 2024 Article: 119

   

7. Long-term survival after anti-PD-1 discontinuation in advanced cutaneous squamous cell carcinoma (cSCC): a proof of concept of benefit of concomitant cemiplimab and radiotherapy

   • Barbara Bailly-Caillé
   • Romain Levard
   • Jean-Matthieu L’Orphelin

   Brief Report Open access 07 May 2024 Article: 118

   

8. Overexpressing S100A9 ameliorates NK cell dysfunction in estrogen receptor-positive breast cancer

   • Yansong Liu
   • Mingcui Li
   • Fei Ma

   Research Open access 07 May 2024 Article: 117

   

9. Clinical outcomes of adjuvant nivolumab in resected stage III melanoma: comparison of CheckMate 238 trial and real-world data

   • Justin C. Moser
   • Shailender Bhatia
   • Jeffrey Weber

   Research Open access 07 May 2024 Article: 116

   

10. Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion

    • Ke-Xun Yu
    • Wei-Jie Yuan
    • Yong-Xiang Li

    Review Open access 02 May 2024 Article: 115

    

11. Expression patterns of novel immunotherapy targets in intermediate- and high-grade lung neuroendocrine neoplasms

    • Bence Ferencz
    • Klára Török
    • Balázs Döme

    Research Open access 02 May 2024 Article: 114

    

12. Neutrophil-activating secretome characterizes palbociclib-induced senescence of breast cancer cells

    • Gabriele Favaretto
    • Marianna Nicoletta Rossi
    • Fabrizio Antonangeli

    Research Open access 02 May 2024 Article: 113

    

13. New genetic insights into immunotherapy outcomes in gastric cancer via single-cell RNA sequencing and random forest model

    • Dajun Yu
    • Jie Yang
    • Chao Zhu

    Research Open access 02 May 2024 Article: 112

    

14. Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer

    • Yadong Wang
    • Zhicheng Huang
    • Naixin Liang

    Research Open access 26 April 2024 Article: 111

    

15. Interleukin 33 supports squamous cell carcinoma growth via a dual effect on tumour proliferation, migration and invasion, and T cell activation

    • Graziela Perri
    • Vanessa Garcia Vilas Boas
    • Ana Paula Campanelli

    Research Open access 25 April 2024 Article: 110

    

16. Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study

    • Sara Maher
    • Hesham A. Elmeligy
    • Manal Kamel

    Research Open access 25 April 2024 Article: 109

    

17. A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis

    • Qingyang Lei
    • Shanshan Zhen
    • Yi Zhang

    Research Open access 20 April 2024 Article: 108

    

18. A phase I trial of autologous RAK cell immunotherapy in metastatic renal cell carcinoma

    • Jing Xu
    • Wen Zhang
    • Jie Ma

    Research Open access 20 April 2024 Article: 107

    

19. Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study

    • Francesco Massari
    • Matteo Santoni
    • Joaquim Bellmunt

    Research Open access 18 April 2024 Article: 106

    

20. Correction to: Dominant‑negative transforming growth factor‑β receptor‑armoured mesothelin‑targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer

    • Ke Li
    • Jing Xu
    • Yu Kang

    Correction Open access 18 April 2024 Article: 105

21. Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell acute lymphoblastic leukemia

    • Sha Ma
    • Ying Wang
    • Kailin Xu

    Research Open access 17 April 2024 Article: 104

    

22. Intratumor injection of BCG Ag85A high-affinity peptides enhanced anti-tumor efficacy in PPD-positive melanoma

    • Lanqun Qin
    • Guiying Zhang
    • Zhengyun Zou

    Research Open access 17 April 2024 Article: 103

    

23. TLR5 agonist in combination with anti-PD-1 treatment enhances anti-tumor effect through M1/M2 macrophage polarization shift and CD8⁺ T cell priming

    • Junseok Lee
    • Keon-Il Im
    • Seok-Goo Cho

    Research Open access 17 April 2024 Article: 102

    

24. Expansion of tumor-infiltrating lymphocytes from head and neck squamous cell carcinoma to assess the potential of adoptive cell therapy

    • Sangjoon Choi
    • Mofazzal Hossain
    • Hee Jin Lee

    Research Open access 17 April 2024 Article: 101

    

25. Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma

    • Sophia Stock
    • Luisa Fertig
    • Sebastian Kobold

    Research Open access 17 April 2024 Article: 100

    

26. T-cell subsets and cytokines are indicative of neoadjuvant chemoimmunotherapy responses in NSCLC

    • Ling Yi
    • Ziwei Xu
    • Yi Han

    Research Open access 15 April 2024 Article: 99

    

27. Incorporating IL7 receptor alpha signaling in the endodomain of B7H3-targeting chimeric antigen receptor T cells mediates antitumor activity in glioblastoma

    • Nithidol Sakunrangsit
    • Nattarika Khuisangeam
    • Supannikar Tawinwung

    Research Open access 15 April 2024 Article: 98

    

28. Integrating bulk and single-cell sequencing data to construct a Scissor⁺ dendritic cells prognostic model for predicting prognosis and immune responses in ESCC

    • Maosheng Cheng
    • Jianqi Xiong
    • Shuang Chen

    Research Open access 15 April 2024 Article: 97

    

29. CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival

    • Jessica Wedig
    • Shrina Jasani
    • Thomas A. Mace

    Research Open access 15 April 2024 Article: 96

    

30. Dual-loss of PBRM1 and RAD51 identifies hyper-sensitive subset patients to immunotherapy in clear cell renal cell carcinoma

    • Ziyang Xu
    • Wenbin Jiang
    • Jiejie Xu

    Research Open access 12 April 2024 Article: 95

    

31. Bifidobacterium modulation of tumor immunotherapy and its mechanism

    • Bo Pei
    • Shixuan Peng
    • Fuxiang Zhou

    Review Open access 02 April 2024 Article: 94

    

32. The prognostic and potentially immunomodulatory role of cartilage oligomeric matrix protein in patients with gastric and esophageal adenocarcinoma

    • Konstantinos S. Papadakos
    • Gilar Gorji-Bahri
    • Anna M. Blom

    Research Open access 02 April 2024 Article: 93

    

33. Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy

    • Jhen-Yu Chen
    • Po-Yu Lin
    • Kevin Chih-Yang Huang

    Research Open access 02 April 2024 Article: 92

    

34. circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis

    • Qingtao Liu
    • Pei Xu
    • Fangbao Ding

    Research Open access 30 March 2024 Article: 91

    

35. IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models

    • Justin Yu
    • Jacob Gadwa
    • Sana D. Karam

    Research Open access 30 March 2024 Article: 90

    

36. Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours

    • Manish R. Patel
    • Melissa Johnson
    • Lillian L. Siu

    Research Open access 30 March 2024 Article: 89

    

37. Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression

    • Jingbo Ma
    • Jian Tan
    • Keqiang Liu

    Research Open access 30 March 2024 Article: 88

    

38. The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy

    • Wenxin Lu
    • Guangyu Wu
    • Liwei Wang

    Research Open access 30 March 2024 Article: 87

    

39. SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue

    • Kelly J. Gregory
    • Holly Mason
    • Sallie S. Schneider

    Brief Report Open access 30 March 2024 Article: 86

    

40. TGF-β1 and TGF-βR1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation

    • Zihao Niu
    • Peng Sun
    • Guojun Li

    Research Open access 30 March 2024 Article: 85

    

41. IL-2 promotes expansion and intratumoral accumulation of tumor infiltrating dendritic cells in pancreatic cancer

    • Tingting Gong
    • Xinyang Huang
    • Qi Wang

    Research Open access 30 March 2024 Article: 84

    

42. 23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling

    • Zeping Fan
    • Yaru Cui
    • Wenbin Duan

    Research Open access 30 March 2024 Article: 83

    

43. DR30318, a novel tri-specific T cell engager for Claudin 18.2 positive cancers immunotherapy

    • Zhe Ma
    • Zhenxing Zhou
    • Lushan Yu

    Research Open access 30 March 2024 Article: 82

    

44. Characterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models

    • Hongyu Xue
    • Zhimin Zhang
    • Kai Chen

    Research Open access 30 March 2024 Article: 81

    

45. Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth

    • Andrew N. Wilkinson
    • Rui Chen
    • Sherry Y. Wu

    Research Open access 30 March 2024 Article: 80

    

46. Efficacy of immune checkpoint inhibitors differs in various status of carcinoma: a study based on 29 cohorts with 3255 participants

    • Chunlan Wu
    • Yujun Ke
    • Xianhe Xie

    Research Open access 30 March 2024 Article: 79

    

47. Lipid droplets-related Perilipin-3: potential immune checkpoint and oncogene in oral squamous cell carcinoma

    • Yijia He
    • Lingyun Liu
    • Liang Ding

    Research Open access 30 March 2024 Article: 78

    

48. Targeting osteosarcoma with canine B7-H3 CAR T cells and impact of CXCR2 Co-expression on functional activity

    • Jennifer W. Cao
    • Jessica Lake
    • Steven Dow

    Research Open access 30 March 2024 Article: 77

    

49. PGRN inhibits CD8⁺T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM

    • Ting Zhou
    • Husun Qian
    • Bianqin Guo

    Research Open access 30 March 2024 Article: 76

    

50. Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer

    • Kaiqi Zhang
    • Yuan Xu
    • Kai Yin

    Research Open access 27 March 2024 Article: 75