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The Journal of Membrane Biology - Editors Choice

2022 - Highlighted articles

Cholesterol Stiffening of Lipid Membranes

Biomembrane order, dynamics, and other essential physicochemical parameters are controlled by cholesterol, a major component of mammalian cell membranes. Although cholesterol is...

Fathima T. Doole, Teshani Kumarage, Rana Ashkar, and Michael F. Brown in The Journal of Membrane Biology (2022)

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Interdigitation-Induced Order and Disorder in Asymmetric Membranes

We studied the transleaflet coupling of compositionally asymmetric liposomes in the fluid phase. The vesicles were produced by cyclodextrin-mediated lipid exchange and contained dipalmitoyl phosphatidylcholine (DPPC) in the inner leaflet and...

Moritz P. K. FreweinPaulina PillerEnrico F. Semeraro... in The Journal of Membrane Biology (2022)

Interdigitation-Induced Order and Disorder in Asymmetric Membranes

Forces of Change: Optical Tweezers in Membrane Remodeling Studies

Optical tweezers allow precise measurement of forces and distances with piconewton and nanometer precision, and have thus been instrumental in elucidating the mechanistic details of various biological processes. Some examples include...

Sudheer K. Cheppali,  Raviv Dharan, and Raya Sorkin in The Journal of Membrane Biology (2022)

Forces of Change: Optical Tweezers in Membrane Remodeling Studies

Insights into Membrane Curvature Sensing and Membrane Remodeling by Intrinsically Disordered Proteins and Protein Regions

Cellular membranes are highly dynamic in shape. They can rapidly and precisely regulate their shape to perform various cellular functions. The protein’s ability to sense membrane curvature is essential in various biological events such as cell signaling and membrane trafficking. As they are bound...

Chandra Has, P. Sivadas, and Sovan Lal Das in The Journal of Membrane Biology (2022)

Insights into Membrane Curvature Sensing and Membrane Remodeling by Intrinsically Disordered Proteins and Protein Regions


2020 - Highlighted articles

Nicorandil Affects Mitochondrial Respiratory Chain Function by Increasing Complex III Activity and ROS Production in Skeletal Muscle Mitochondria

Adenosine triphosphate (ATP)-dependent potassium channels openers (KATP) protect skeletal muscle against function impairment through the activation of the mitochondrial KATP channels (mitoKATP). Previous reports...

E. Sánchez-DuarteC. Cortés-RojoL. A. Sánchez-Briones… in The Journal of Membrane Biology (2020)

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Partial Reactions of the Na,K-ATPase: Determination of Activation Energies and an Approach to Mechanism

Kinetic experiments were performed with preparations of kidney Na,K-ATPase in isolated membrane fragments or reconstituted in vesicles to obtain information of the activation energies under turnover conditions...

Hans-Jürgen Apell and Milena Roudna in The Journal of Membrane Biology (2020)

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Experimental and Computational Characterization of Oxidized and Reduced Protegrin Pores in Lipid Bilayers

Protegrin-1 (PG-1), an 18-residue β-hairpin stabilized by two disulfide bonds, is a member of a family of powerful antimicrobial peptides which are believed to act through membrane permeabilization. Here we us...

Mykola V. RodninVictor Vasquez-MontesBinod Nepal… in The Journal of Membrane Biology (2020)

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Towards a Quantitative Understanding of Protein–Lipid Bilayer Interactions at the Single Molecule Level: Opportunities and Challenges

Protein–lipid interfaces are among the most fundamental in biology. Yet applying conventional techniques to study the biophysical attributes of these systems is challenging and has left many unknowns. For exam...

Gavin M. King and Ioan Kosztin in The Journal of Membrane Biology (2020)

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How We Came to Understand the “Tumultuous Chemical Heterogeneity” of the Lipid Bilayer Membrane

The path to our modern understanding of the structure of the lipid bilayer membrane is a long one that can be traced from today perhaps as far back as Benjamin Franklin in the eighteenth century. Here, I provi...

William C. Wimley in The Journal of Membrane Biology (2020)

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