Clinical trials: relevance of correlation between treatment responses T. J. M. Cleophas CLINICAL TRIALS Pages: 1 - 6
Time course of physical and psychological responses to selegiline monotherapy in newly diagnosed, idiopathic parkinosonism C. KirollosA. CharlettS. M. Dobbs CLINICAL TRIALS Pages: 7 - 18
Use of benzodiazepines in the Italian general population: prevalence, pattern of use and risk factors for use N. MagriniA. VaccheriN. Montanaro PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Pages: 19 - 25
Comparison of dose standard units for drug utilisation studies J. MerloA. WesslingA. Melander PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Pages: 27 - 30
Xamoterol improves right ventricular systolic and diastolic function in pulmonary heart disease R. M. OliverJ. S. FlemingD. G. Waller PHARMACODYNAMICS Pages: 31 - 36
Influence of age on venodilator effect of isoproterenol and amrinone K. HaradaK. OhashiA. Fujimura PHARMACODYNAMICS Pages: 37 - 40
The effect of aging on the pharmacokinetics and pharmacodynamics of prazosin E. AndrosD. Detmar-HannaJ. G. Gerber PHARMACODYNAMICS Pages: 41 - 46
Multiple-dose clinical pharmacology of the catechol-O-methyl-transferase inhibitor tolcapone in elderly subjects J. DingemanseK. JorgaP. van Brummelen PHARMACODYNAMICS Pages: 47 - 55
A comparison of the pharmacokinetics and pharmacodynamics of cilazapril between Chinese and Caucasian healthy, normotensive volunteers P. J. AndersonJ. A. J. H. CritchleyB. Tomlinson PHARMACODYNAMICS Pages: 57 - 62
Comparison between a bid and a tid regimen: improved compliance with no improved antihypertensive effect J. P. BoisselO. MeillardR. Benghozi PHARMACODYNAMICS Pages: 63 - 67
Metabolism of paracetamol in children with chronic liver disease S. S. Al-ObaidyP. J. McKiernanP. S. Collier PHARMACOKINETICS AND DISPOSITION Pages: 69 - 76
The effect of hypoxaemia on drug disposition in chronic respiratory failure D. RowettK. LatimerReceived: February 1995/Accepted May PHARMACOKINETICS AND DISPOSITION Pages: 77 - 82
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a “cocktail” of antipyrine and nifedipine V. L. LanchoteW. C. PingS. R. C. J. Santos PHARMACOKINETICS AND DISPOSITION Pages: 83 - 89
Extrahepatic glucuronidation of propofol in man: possible contribution of gut wall and kidney A. A. RaoofL. J. van ObberghR. K. Verbeeck PHARMACOKINETICS AND DISPOSITION Pages: 91 - 96
Effect of diprafenone on the pharmacokinetics of digoxin R. KoytchevR.-G. AlkenO. Mayer PHARMACOKINETICS AND DISPOSITION Pages: 97 - 100
Nefazodone pharmacokinetics: assessment of nonlinearity, intra-subject variability and time to attain steady-state plasma concentrations after dose escalation and de-escalation R. H. BarbhaiyaU. A. ShuklaP. H. Marathe PHARMACOKINETICS AND DISPOSITION Pages: 101 - 107
Measurement of 5-fluorouracil in scalp hair: a possible index of patient compliance with oral adjuvant chemotherapy T. UematsuM. NakashimaT. Masuike PHARMACOKINETICS AND DISPOSITION Pages: 109 - 113
Variability in the plasma protein binding of velnacrine (1-hydroxy tacrine hydrochloride) A potential agent for Alzheimer’s disease D. M. WoodJ. M. FordC. J. C. Roberts PHARMACOKINETICS AND DISPOSITION Pages: 115 - 119
Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine G. MuralidharanJ. K. CooperK. K. Midha PHARMACOKINETICS AND DISPOSITION Pages: 121 - 128
Lack of a kinetic interaction between fluconazole and mexiletine K. UenoR. YamaguchiA. Iwai PHARMACOKINETICS AND DISPOSITION Pages: 129 - 131
Coumarin 7-hydroxylation in long-term adherents of a strict uncooked vegan diet A.-L. RaumaA. RautioH. Mykkänen PHARMACOKINETICS AND DISPOSITION Pages: 133 - 137
Gender does not affect the degree of induction of tirilazad clearance by phenobarbital J. C. FleishakerL. K. PearsonG. R. Peters PHARMACOKINETICS AND DISPOSITION Pages: 139 - 145
The pharmacokinetics of extended release felodipine in children D. L. BloweyI. MoncicaG. Koren LETTER TO THE EDITORS Pages: 147 - 148