1. Thalidomide-induced neuropathy and genetic differences in drug metabolism

   • C. C. Harland
   • G. B. Steventon
   • J. R. Marsden

   Pharmacodynamics Pages: 1 - 6

2. Tonic versus phasic pain: dose-related effects of ketoprofen

   • T. Hummel
   • S. Menzel
   • H. Huber

   Pharmacodynamics Pages: 7 - 14

3. Effects of lisinopril on congestive heart failure in normotensive patients with diastolic dysfunction but intact systolic function

   • C. C. Lang
   • A. R. Rahman
   • N. Kennedy

   Pharmacodynamics Pages: 15 - 19

4. Lisinopril is neutral to insulin sensitivity and serum lipoproteins in essential hypertensive patients

   • Ch. Thürig
   • L. Böhlen
   • W. Riesen

   Pharmacodynamics Pages: 21 - 26

5. Antianginal effect of conventional and controlled release diltiazem in stable angina pectoris

   • K. Boman
   • L. G. Karlsson
   • S. O. R. Olsson

   Pharmacodynamics Pages: 27 - 30

6. Diuretic-related hypokalaemia: the role of diuretics, potassium supplements, glucocorticoids and β₂-adrenoceptor agonists

   • P. Widmer
   • R. Capaul
   • R. Hoigné

   Pharmacodynamics Pages: 31 - 36

7. Pharmacodynamic modelling of the drug-induced downregulation of a β₂-adrenoceptor mediated response and lack of restoration of receptor function after a single high dose of prednisone

   • R. E. Jonkers
   • M. C. P. Braat
   • C. J. van Boxtel

   Pharmacodynamics Pages: 37 - 44

8. Comparison of the effects of atropine in vivo and ex vivo (radioreceptor assay) after oral and intramuscular administration to man

   • C. Volz-Zang
   • T. Waldhäuser
   • B. Schulte

   Pharmacodynamics Pages: 45 - 49

9. Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study

   • I. Ieiri
   • W. Goto
   • K. Ohtsubo

   Pharmacodynamics Pages: 51 - 56

10. A double-blind controlled evaluation of the sebosuppressive activity of topical erythromycin-zinc complex

    • C. Piérard-Franchimont
    • V. Goffin
    • H. Jacoby

    Pharmacodynamics Pages: 57 - 60

11. Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

    • J. Lundahl
    • C. G. Regårdh
    • G. Johnsson

    Pharmacodynamics Pages: 61 - 67

12. Pharmacokinetics and pharmacodynamics of a single dose of recombinant human growth hormone after subcutaneous administration by jet-injection: comparison with conventional needle-injection

    • A. Verhagen
    • J. T. Ebels
    • A. A. Dogterom

    Pharmacodynamics Pages: 69 - 72

13. European postmarketing surveillance of ramipril in hypertension

    • D. H. Lawson
    • K. Bridgman
    • P. Stonier

    Pharmacoepidemiology And Prescription Pages: 73 - 79

14. Flucloxacillin associated cholestatic hepatitis

    • D. H. G. Crawford
    • H. P. Roeser
    • P. Purcell

    Pharmacoepidemiology And Prescription Pages: 81 - 85

15. References used in a Drug Information Centre

    • A. LLerena
    • B. Öhman
    • G. Alván

    Pharmacoepidemiology And Prescription Pages: 87 - 89

16. Rising dose study of safety and tolerance of flunarizine

    • A. Handforth
    • T. Mai
    • D. M. Treiman

    Clinical Trials Pages: 91 - 94

17. Czech and Slovak spirapril intervention study (CASSIS)

    • J. Widimský
    • O. Uhlíř
    • P. Jerie

    Clinical Trials Pages: 95 - 102

18. A placebo controlled clinical trial investigating the efficacy of a homeopathic after-bite gel in reducing mosquito bite induced erythema

    • N. Hill
    • C. Stam
    • R. A. van Haselen

    Clinical Trials Pages: 103 - 108

19. Reduced platelet phenolsulphotransferase activity towards dopamine and 5-hydroxytryptamine in migraine

    • A. L. Jones
    • G. L. Rubin
    • W. Colvin

    Pharmacokinetics And Disposition Pages: 109 - 114

20. Effects of cimetidine on pharmacokinetics and pharmacodynamics of losartan, an AT₁-selective non-peptide angiotensin II receptor antagonist

    • M. R. Goldberg
    • M. W. Lo
    • P. Högland

    Pharmacokinetics And Disposition Pages: 115 - 119

21. Increase in plasma propranolol caused by nicardipine is dependent on the delivery rate of propranolol

    • A. G. Dupont
    • I. Vercruysse
    • D. L. Massart

    Pharmacokinetics And Disposition Pages: 121 - 125

22. Pharmacokinetics of thiopental after single and multiple intravenous doses in critical care patients

    • H. Russo
    • J. Brès
    • B. Roquefeuil

    Pharmacokinetics And Disposition Pages: 127 - 137

23. Limitations of the maximum entropy principle in devising drug input rate

    • G. Paintaud
    • C. W. Maboundou
    • G. Alván

    Pharmacokinetics And Disposition Pages: 139 - 143

24. Announcements

    Announcement Pages: 144 - 144

25. Abstracts of the 5th annual meeting of the German society of clinical pharmacology and therapy on recent issues of pharmacotherapy

    Abstract Pages: A145 - A166