1. European Journal of Clinical Pharmacology becomes the official organ of European Association for Clinical Pharmacology and Therapeutics

   • Rune Dahlqvist
   • Rolf Lange
   • Folke Sjöqvist

   Editorial Pages: 317 - 318

2. Presentation of the 1st Congress of the European Association of Clinical Pharmacology and Therapeutics

   • Georges Cheymol

   Editorial Pages: 319 - 319

3. Changing managing editor

   • Rune Dahlqvist
   • Rolf Lange

   Personalities Pages: 320 - 320

4. Legal opioid consumption in Denmark 1981–1993

   • T. Groth Clausen
   • J. Eriksen
   • F. Molke Borgbjerg

   Pharmacoepidemiology and Prescription Pages: 321 - 325

5. Dysfunction in the β₂-adrenergic signal pathway in patients with insulin dependent diabetes mellitus (IDDM) and unawareness of hypoglycaemia

   • T. S. Trovik
   • A. Vaartun
   • R. Jorde

   Pharmacodynamics Pages: 327 - 332

6. Low-dose Iloprost infusion improves insulin action and non-oxidative glucose metabolism in hypertensive patients

   • G. Paolisso
   • A. Gambardella
   • M. Varricchio

   Pharmacodynamics Pages: 333 - 338

7. Humoral and haemodynamic effects of idrapril calcium, the prototype of a new class of ACE-inhibitors, in essential hypertensive patients

   • S. Taddei
   • L. Ghiadoni
   • A. Coppini

   Pharmacodynamics Pages: 339 - 343

8. Determination of (+)- and (-)-nicardipine concentrations in human serum and their correlation with the antihypertensive effect after oral administration of racemic nicardipine

   • T. Iwaoka
   • J. Inoue
   • S. Higuchi

   Pharmacodynamics Pages: 345 - 349

9. Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension

   • Scott H. Fettner
   • S. Pai
   • C. R. Banfield

   Pharmacodynamics Pages: 351 - 359

10. Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts

    • J. W. de Vos
    • J. G. R. Ufkes
    • W. van den Brink

    Pharmacokinetics and Disposition Pages: 361 - 366

11. In vitro inhibition of midazolam and quinidine metabolism by flavonoids

    • A. U. Freiburghaus
    • H. R. Ha
    • F. Follath

    Pharmacokinetics and Disposition Pages: 367 - 371

12. The effect of pH on the buccal and sublingual absorption of captopril

    • J. C. McElnay
    • T. A. Al-Furaih
    • D. P. Nicholls

    Pharmacokinetics and Disposition Pages: 373 - 379

13. Determination of phenobarbitone population clearance values for South African children

    • J. H. Botha
    • A. L. Gray
    • R. Miller

    Pharmacokinetics and Disposition Pages: 381 - 383

14. Furosemide disposition in patients on CAPD

    • U. Martin
    • L. F. Prescott
    • R. J. Winney

    Pharmacokinetics and Disposition Pages: 385 - 390

15. Effects of lansoprazole on pharmacokinetics and metabolism of theophylline

    • T. Kokufu
    • N. Ihara
    • K. Nakajima

    Pharmacokinetics and Disposition Pages: 391 - 395

16. Methyldopa kinetics before and after ingestion of methyldopa for eight weeks

    • N. Campbell
    • S. Robertson
    • Y. Tam

    Pharmacokinetics and Disposition Pages: 397 - 400

17. Book review

    • J. K. Aronson

    BookReview Pages: 401 - 402

18. Announcements

    Announcement Pages: 403 - 403

19. Abstracts of the 1st international conference on new areas of pharmaceutical research

    Abstract Pages: A405 - A419