Drug discrimination is a continuous rather than a quantal process following training on a VI-TO schedule of reinforcement Robert J. BarrettWilliam F. CaulRandy L. Smith Review Pages: 289 - 296
Continuous or quantal data in drug discrimination experiments is a measurement issue not a reinforcement issue David V. GauvinFrank A. Holloway Commentary Pages: 297 - 297
Disadvantages of quantal drug discrimination procedures Donald A. Overton Commentary Pages: 298 - 299
Commentary on “Drug discrimination is a continuous rather than a quantal process following training on a VI-TO schedule of reinforcement” by Barrett et al. M. W. Emmett-Oglesby Commentary Pages: 300 - 301
Reply to comments by Overton, Emmett-Oglesby and Gauvin and Holloway Robert J. BarrettWilliam F. CaulRandy L. Smith Rebuttal Pages: 302 - 303
Development of acute tolerance after oral doses of diazepam and flunitrazepam John IngumRoald BjørklundJørg Mørland Original Investigations Pages: 304 - 310
An acute effect of triazolam on muscarinic cholinergic receptor binding in the human brain measured by positron emission tomography Tetsuya SuharaOsamu InoueYukio Tateno Original Investigations Pages: 311 - 317
Reduction in ATP-sensitive potassium channel-mediated antinociception in diabetic mice Junzo KameiNaoya KawashimaYutaka Kasuya Original Investigations Pages: 318 - 321
Serotonin-induced platelet intracellular calcium mobilization in depressed patients Ichiro KusumiTsukasa KoyamaItaru Yamashita Original Investigations Pages: 322 - 327
A comparison of the effects of the D1 receptor antagonists SCH 23390 and SCH 39166 on suppression of feeding behavior by the D1 agonist SKF38393 Philip TerryJonathan L. Katz Original Investigations Pages: 328 - 333
Flumazenil exerts intrinsic activity on sleep EEG and nocturnal hormone secretion in normal controls A. SteigerJ. GuldnerF. Holsboer Original Investigations Pages: 334 - 338
Using a computer model to explore impairments of acquisition processes following ingestion of diazepam Gregory G. BrownJohn L. WoodardJill B. Rich Original Investigations Pages: 339 - 345
Effects of alcohol pretreatment on human marijuana self-administration L. D. ChaitJ. L. Perry Original Investigations Pages: 346 - 350
Discriminative stimulus properties of the benzodiazepine receptor inverse agonist methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate (DMCM) Lynn G. KirbyGrace A. RowanIrwin Lucki Original Investigations Pages: 351 - 360
A comparison of the effects of the novel muscarinic receptor agonists L-689,660 and AF102B in tests of reference and working memory G. R. DawsonP. BayleyS. D. Iversen Original Investigations Pages: 361 - 368
An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats S. J. KitchenerC. T. Dourish Original Investigations Pages: 369 - 377
Effects of the calcium antagonist isradipine on cocaine intravenous self-administration in rats M. Cristina MartellottaAlexander KuzminWalter Fratta Original Investigations Pages: 378 - 380
Factors influencing the reinforcing and subjective effects of ephedrine in humans L. D. Chait Original Investigations Pages: 381 - 387
A mouse model of early social interactions after prenatal drug exposure: a genetic investigation Giovanni LaviolaMaria Livia TerranovaAubrey Manning Original Investigations Pages: 388 - 394
Discriminative stimulus effects of alpidem, a new imidazopyridine anxiolytic D. J. SangerB. Zivkovic Original Investigations Pages: 395 - 403
Nimodipine and haloperidol attenuate behavioural sensitization to cocaine but only nimodipine blocks the establishment of conditioned locomotion induced by cocaine Allan R. ReimerMathew T. Martin-Iverson Original Investigations Pages: 404 - 410
Influence of caffeine on information processing stages in well rested and fatigued subjects Monicque M. LoristJan SnelAlbert Kok Original Investigations Pages: 411 - 421
Aversive properties of theκ opioid agonist U50,488 in the week-old rat pup Gordon A. BarrShaoning WangSusan Carden Original Investigations Pages: 422 - 428
Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats Kirsten M. KrebsMark A. Geyer Original Investigations Pages: 429 - 437
Subjective and cardiovascular responses to nicotine combined with caffeine during rest and casual activity Kenneth A. PerkinsJoan E. SextonAnnette Scierka Original Investigations Pages: 438 - 444
Nicotine-induced place preferences following prior nicotine exposure in rats Mohammed ShoaibIan P. StolermanR. Channi Kumar Original Investigations Pages: 445 - 452
Potentiation of the Ambulation-increasing effect induced by combined administration of MK-801 with ethanol in mice Hisashi Kuribara Original Investigations Pages: 453 - 456
Pharmacological analysis of the rate-decreasing effects of mu and kappa opioids in pigeons Adande J. MattoxMitchell J. PickerLinda A. Dykstra Original Investigations Pages: 457 - 462
Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents Guy GriebelJean-Luc MoreauJames R. Martin Original Investigations Pages: 463 - 470
Diphenylhydantoin potentiates the EEG and behavioural effects induced by N-methyl-D-aspartate antagonists in rats P. PopoliA. PèzzolaS. Sagratella Original Investigations Pages: 471 - 475
Post-training minaprine enhances memory storage in mice: involvement of D1 and D2 dopamine receptors Stefano Puglisi-AllegraSimona CabibClaudio Castellano Original Investigations Pages: 476 - 480
Time course of the effects of adrenalectomy and corticosterone replacement on 5-HT1A receptors and 5-HT uptake sites in the hippocampus and dorsal raphe nucleus of the rat brain: an autoradiographic analysis Shanaz M. Tejani-ButtDaniel M. Labow Original Investigations Pages: 481 - 486
Prepulse inhibition of the acoustic startle response of rats is reduced by 6-hydroxydopamine lesions of the medial prefrontal cortex Michael BubserMichael Koch Original Investigations Pages: 487 - 492
Effects of alpha-2 adrenoceptor antagonists on rough-and-tumble play in juvenile rats: evidence for a site of action independent of non-adrenoceptor imidazoline binding sites Stephen M. SiviyAnne E. FleischhauerDale M. Atrens Original Investigations Pages: 493 - 499
Effects of morphine and naloxone on behaviour in the hot plate test: an ethopharmacological study in the rat Emilio F. EspejoLouis StinusDiego Mir Original Investigations Pages: 500 - 510
The NMDA receptor antagonist dizocilpine differentially affects environment-dependent and environment-independent ethanol tolerance Gyula SzabóBoris TabakoffPaula L. Hoffman Original Investigations Pages: 511 - 517
SDZ 208-911, an amino-ergoline with partial dopamine agonist properties, dose dependently increases cocaine self-administration in the rat Luigi PulvirentiDiana SmithGeorge F. Koob Original Investigations Pages: 518 - 520
Purinergic drugs and calcium channel antagonists attenuate the withdrawal syndrome from barbital A. GermanyE. Contreras Original Investigations Pages: 521 - 526
Effects of acute selective 5-HT1, 5-HT2, 5-HT3 receptor andα 2 adrenoceptor blockade on naloxone-induced antinociception M. J. Katharine WalkerConstantine X. PoulosA. D. Le Original Investigations Pages: 527 - 533
Prenatal nicotine exposure increased duration of nicotine-induced analgesia in adult rats Vlasta K. ZbuzekChristina W. Y. Chin Original Investigations Pages: 534 - 538
Effects of chronic treatment with valproate on serotonin-1A receptor binding and function Leena KhaitanJoseph R. CalabreseCraig A. Stockmeier Original Investigations Pages: 539 - 542
Raised corticosterone in the rat after exposure to the elevated plus-maze Sandra E. FileHelio Zangrossi JrPeter S. Mabbutt Original Investigations Pages: 543 - 546
Influence of repeated cocaine exposure on the endocrine and behavioral responses to stress in rats Andrew D. LevyPeter A. RittenhouseLouis D. Van de Kar Original Investigations Pages: 547 - 554
Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy Lucyna Antkiewicz-MichalukJerzy MichalukJerzy Vetulani Original Investigations Pages: 555 - 560
Neuroendocrine effects of sumatriptan J. R. E. HerdmanN. J. DelvaP. J. Cowen Original Investigations Pages: 561 - 564
Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey M. G. MatheusR. L. NogueiraF. S. Guimarães Original Investigations Pages: 565 - 569
One-trial tolerance to the effects of chlordiazepoxide on the elevated plus maze may be due to locomotor habituation, not repeated drug exposure Gerard R. DawsonSusan P. CrawfordMark D. Tricklebank Original Investigations Pages: 570 - 572