1. In memoriam Thomas Gebel

   • Jan G. Hengstler
   • Hermann Bolt
   • Robert Landsiedel

   Memoriam Open access 14 March 2023 Pages: 1193 - 1194

   

2. A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)

   • Zeng-Jin Wen
   • Yi-Jing Wei
   • Yin-Feng Zhang

   Review Article 22 March 2023 Pages: 1195 - 1245

   

3. Toxicology of 3-monochloropropane-1,2-diol and its esters: a narrative review

   • Elena Fattore
   • Alessia Lanno
   • Enrico Davoli

   Review Article 24 February 2023 Pages: 1247 - 1265

   

4. Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methods

   • Beate I. Escher
   • Rolf Altenburger
   • Kathrin Fenner

   Regulatory Toxicology Open access 23 March 2023 Pages: 1267 - 1283

   

5. A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats

   • Viorica Dinca
   • Anca Oana Docea
   • Aristidis Tsatsakis

   Regulatory Toxicology Open access 09 March 2023 Pages: 1285 - 1298

   

6. The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity

   • Michael Aschner
   • Anatoly V. Skalny
   • Alexey A. Tinkov

   Inorganic Compounds 18 March 2023 Pages: 1299 - 1318

   

7. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat

   • Anja Lehmann
   • Ina Geburek
   • Christoph Hethey

   Toxicokinetics and Metabolism Open access 11 March 2023 Pages: 1319 - 1333

   

8. Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study alcoholic steatohepatitis by LC–MS-based untargeted metabolomics

   • Elias Iturrospe
   • Rani Robeyns
   • Adrian Covaci

   oxicogenomics and Omics Technologies 24 February 2023 Pages: 1335 - 1353

   

9. Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2

   • Paige C. Mundy
   • Alicia Werner
   • Pamela J. Lein

   Molecular Toxicology Open access 13 March 2023 Pages: 1355 - 1365

   

10. Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor

    • Marie H. Deventer
    • Mattias Persson
    • Christophe P. Stove

    Molecular Toxicology 28 February 2023 Pages: 1367 - 1384

    

11. Lysosomal dysfunction in Schwann cells is involved in bortezomib-induced peripheral neurotoxicity

    • Zhanxun Wu
    • Wenping Yan
    • Jiaying Wu

    Organ Toxicity and Mechanisms 24 February 2023 Pages: 1385 - 1396

    

12. Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice

    • Nga T. Nguyen
    • David S. Umbaugh
    • Hartmut Jaeschke

    Organ Toxicity and Mechanisms 16 March 2023 Pages: 1397 - 1412

    

13. Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery

    • Manuel Haas
    • Karina Wirachowski
    • Jörg Fahrer

    Genotoxicity and Carcinogenicity Open access 16 March 2023 Pages: 1413 - 1428

    

14. Organoid-based 3D in vitro microphysiological systems as alternatives to animal experimentation for preclinical and clinical research

    • Chrianjay Mukhopadhyay
    • Manash K. Paul

    Letter to the Editor, News and Views 14 March 2023 Pages: 1429 - 1431

    

15. ECHA ARN documents: chemical grouping without a toxicological rationale

    • Andreas Natsch
    • Greg Adamsson
    • Vanessa Rocha

    Letter to the Editor, News and Views Open access 22 March 2023 Pages: 1433 - 1437