1. The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells

   • Sigurd Lenzen
   • Volodymyr I. Lushchak
   • Fritz Scholz

   Review Article Open access 13 April 2022 Pages: 1915 - 1920

   

2. Recommendations on dose level selection for repeat dose toxicity studies

   • Fiona Sewell
   • Marco Corvaro
   • Richard Lewis

   Review Article Open access 29 April 2022 Pages: 1921 - 1934

   

3. Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi

   • Francesca Caloni
   • Isabella De Angelis
   • Thomas Hartung

   Review Article Open access 03 May 2022 Pages: 1935 - 1950

   

4. Reversal of genetic brain iron accumulation by N,N′-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice

   • Ruiying Cheng
   • Rajitha Gadde
   • Jonghan Kim

   Inorganic Compounds 21 April 2022 Pages: 1951 - 1962

   

5. Medaka embryos as a model for metabolism of anabolic steroids

   • Lingyu Liu
   • Leonie Hobohm
   • Annekathrin M. Keiler

   Toxicokinetics and Metabolism Open access 30 March 2022 Pages: 1963 - 1974

   

6. Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

   • Masato Ooka
   • Jinghua Zhao
   • Menghang Xia

   Toxicokinetics and Metabolism Open access 18 April 2022 Pages: 1975 - 1987

   

7. In silico, in vitro, and in vivo human metabolism of acetazolamide, a carbonic anhydrase inhibitor and common “diuretic and masking agent” in doping

   • Francesco P. Busardò
   • Alfredo F. Lo Faro
   • Jeremy Carlier

   Toxicokinetics and Metabolism 11 April 2022 Pages: 1989 - 2001

   

8. A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome

   • Weiqian Wang
   • Yan Chen
   • Zhengtao Wang

   Toxicogenomics and Omics Technologies Open access 31 March 2022 Pages: 2003 - 2019

   

9. Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3

   • Wei-Ting Chang
   • Jhih-Yuan Shih
   • Chon-Seng Hong

   Organ Toxicity and Mechanisms 19 April 2022 Pages: 2021 - 2032

   

10. microRNAs signatures as potential biomarkers of structural cardiotoxicity in human-induced pluripotent stem-cell derived cardiomyocytes

    • Vitalina Gryshkova
    • Isabel Lushbough
    • Jean-Pierre Valentin

    Organ Toxicity and Mechanisms 29 April 2022 Pages: 2033 - 2047

    

11. Circular RNA circNIPBL promotes NNK-induced DNA damage in bronchial epithelial cells via the base excision repair pathway

    • Yufei Liu
    • Qiuhan Hua
    • Yiguo Jiang

    Genotoxicity and Carcinogenicity 18 April 2022 Pages: 2049 - 2065

    

12. Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

    • Byron Kuo
    • Marc A. Beal
    • Carole L. Yauk

    Genotoxicity and Carcinogenicity Open access 21 April 2022 Pages: 2067 - 2085

    

13. Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells

    • Audrey Barranger
    • Ludovic Le Hégarat

    Genotoxicity and Carcinogenicity 13 April 2022 Pages: 2087 - 2095

    

14. Polymorphisms of an oncogenic gene, mesothelin, predict the risk and prognosis of gastric cancer in a Chinese Han population

    • Kuan Shen
    • Kanghui Liu
    • Li Yang

    Genotoxicity and Carcinogenicity 09 April 2022 Pages: 2097 - 2111

    

15. Chicken heterophils extracellular traps act as early effectors against cyclopiazonic acid dependent upon NADPH oxidase, ROS and glycolysis

    • Liqiang Jiang
    • Shuangqiu Li
    • Zhengkai Wei

    Biologics 04 May 2022 Pages: 2113 - 2122

    

16. Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh

    • Nicholas N. A. Kyei
    • Benedikt Cramer
    • Sabine Gabrysch

    Biologics Open access 19 April 2022 Pages: 2123 - 2138

    

17. Androgenic properties of the dietary supplement 5α-hydroxy-laxogenin

    • Carolin Beer
    • Annekathrin M. Keiler

    Short Communication Open access 28 March 2022 Pages: 2139 - 2142

    

18. News and views

    • Andreas O. Mieland
    • Mandy Beyer
    • Oliver H. Krämer

    Letter to the Editor, News and Views Open access 17 May 2022 Pages: 2143 - 2144