1. Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms

   • Chris S. Pridgeon
   • Constanze Schlott
   • Chris E. P. Goldring

   Review Article Open access 23 January 2018 Pages: 557 - 569

   

2. Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons

   • Mitra C. Geier
   • Anna C. Chlebowski
   • Robert L. Tanguay

   Regulatory Toxicology 01 November 2017 Pages: 571 - 586

   

3. Predicting in vivo effect levels for repeat-dose systemic toxicity using chemical, biological, kinetic and study covariates

   • Lisa Truong
   • Gladys Ouedraogo
   • Matthew Martin

   Regulatory Toxicology Open access 27 October 2017 Pages: 587 - 600

   

4. The effects of the obesogen tributyltin on the metabolism of Sertoli cells cultured ex vivo

   • Ana M. Cardoso
   • Marco G. Alves
   • Luís Rato

   Regulatory Toxicology 09 October 2017 Pages: 601 - 610

   

5. Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods

   • S. Casati
   • K. Aschberger
   • Valérie Zuang

   Regulatory Toxicology Open access 10 November 2017 Pages: 611 - 617

   

6. Protective effect of cadmium-induced autophagy in rat renal mesangial cells

   • Hitomi Fujishiro
   • Ying Liu
   • Douglas M. Templeton

   Inorganic Compounds 07 December 2017 Pages: 619 - 631

   

7. Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines

   • Iris Hansjosten
   • Juliane Rapp
   • Carsten Weiss

   Nanotoxicology 08 November 2017 Pages: 633 - 649

   

8. Toxicokinetic of tris(2-butoxyethyl) phosphate (TBOEP) in humans following single oral administration

   • Wolfgang Völkel
   • Veronika Fuchs
   • Hermann Fromme

   Toxicokinetics and Metabolism 27 September 2017 Pages: 651 - 660

   

9. Arylamine N-acetyltransferase 1 in situ N-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype

   • Raúl A. Salazar-González
   • Eneida Turiján-Espinoza
   • Diana P. Portales-Pérez

   Toxicogenomics 17 October 2017 Pages: 661 - 668

   

10. Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells

    • Sneha Potdar
    • Mayur S. Parmar
    • Jane E. Cavanaugh

    Molecular Toxicology 04 October 2017 Pages: 669 - 677

    

11. P21^Waf1/Cip1 depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway

    • Dandan Han
    • Jian Gao
    • Bo Han

    Molecular Toxicology 22 September 2017 Pages: 679 - 692

    

12. Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells

    • E. N. Dover
    • R. Beck
    • Miroslav Stýblo

    Molecular Toxicology 27 September 2017 Pages: 693 - 704

    

13. PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells

    • Paula Pierozan
    • Oskar Karlsson

    Molecular Toxicology Open access 23 October 2017 Pages: 705 - 716

    

14. ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells

    • Zhuhong Zhang
    • Zhen Ren
    • Nan Mei

    Molecular Toxicology 09 October 2017 Pages: 717 - 728

    

15. Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-d-glucuronide-induced cholestasis in rats

    • Ismael R. Barosso
    • Gisel S. Miszczuk
    • Enrique J. Sánchez Pozzi

    Molecular Toxicology 31 October 2017 Pages: 729 - 744

    

16. Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain

    • Evica Antonijevic
    • Jelena Kotur-Stevuljevic
    • Biljana Antonijevic

    Molecular Toxicology 02 November 2017 Pages: 745 - 757

    

17. t-BuOOH induces ferroptosis in human and murine cell lines

    • Christine Wenz
    • Dagmar Faust
    • Cornelia Dietrich

    Molecular Toxicology 03 October 2017 Pages: 759 - 775

    

18. Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells

    • Guillermo Nicolás Tocchetti
    • Agostina Arias
    • Aldo Domingo Mottino

    Molecular Toxicology 20 October 2017 Pages: 777 - 788

    

19. Roles of cytosolic phospholipase A₂α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed mice

    • Nozomi Fujisawa
    • Wataru Yoshioka
    • Chiharu Tohyama

    Molecular Toxicology Open access 17 October 2017 Pages: 789 - 801

    

20. Respiratory sensitization: toxicological point of view on the available assays

    • Aline Chary
    • Jennifer Hennen
    • Brunhilde Blömeke

    Immunotoxicology 16 October 2017 Pages: 803 - 822

    

21. Effects of arsenolipids on in vitro blood-brain barrier model

    • S. M. Müller
    • F. Ebert
    • T. Schwerdtle

    In vitro systems 20 October 2017 Pages: 823 - 832

    

22. GABA_A receptor subtype selectivity of the proconvulsant rodenticide TETS

    • Brandon Pressly
    • Hai M. Nguyen
    • Heike Wulff

    Organ Toxicity and Mechanisms Open access 16 October 2017 Pages: 833 - 844

    

23. Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

    • Dianke Yu
    • Leihong Wu
    • Baitang Ning

    Organ Toxicity and Mechanisms 24 October 2017 Pages: 845 - 858

    

24. Hepatotoxic combination effects of three azole fungicides in a broad dose range

    • T. Heise
    • F. Schmidt
    • P. Marx-Stoelting

    Organ Toxicity and Mechanisms Open access 16 October 2017 Pages: 859 - 872

    

25. Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats

    • E. Bloch-Shilderman
    • I. Rabinovitz
    • U. Nili

    Organ Toxicity and Mechanisms 10 November 2017 Pages: 873 - 892

    

26. Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells

    • Tzutzuy Ramirez
    • Alexander Strigun
    • Ben van Ravenzwaay

    Organ Toxicity and Mechanisms Open access 30 September 2017 Pages: 893 - 906

    

27. Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone

    • Eric Alejandro Rhon-Calderón
    • Carlos Alejandro Toro
    • Alicia Graciela Faletti

    Reproductive Toxicology 01 November 2017 Pages: 907 - 919

    

28. Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

    • Monika Waldherr
    • Miroslav Mišík
    • Siegfried Knasmüller

    Genotoxicity and Carcinogenicity Open access 07 December 2017 Pages: 921 - 934

    

29. A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells

    • Eleanor C. Wilde
    • Katherine E. Chapman
    • Gareth J. S. Jenkins

    Genotoxicity and Carcinogenicity Open access 06 November 2017 Pages: 935 - 951

    

30. Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver

    • Marzieh Nejabat
    • Teresa Riegler
    • Bettina Grasl-Kraupp

    Genotoxicity and Carcinogenicity Open access 21 December 2017 Pages: 953 - 966

    

31. Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene

    • Alexandra S. Long
    • John W. Wills
    • Paul A. White

    Genotoxicity and Carcinogenicity Open access 24 November 2017 Pages: 967 - 982

    

32. Intestinal toxicity of deoxynivalenol is limited by Lactobacillus rhamnosus RC007 in pig jejunum explants

    • Gisela Romina García
    • Delphine Payros
    • Isabelle P. Oswald

    Biologics 09 October 2017 Pages: 983 - 993

    

33. Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A

    • Elisabeth Limbeck
    • Jens T. Vanselow
    • Angela Mally

    Biologics 02 November 2017 Pages: 995 - 1014

    

34. Highlight report: ‘Big data in the 3R’s: outlook and recommendations’, a roundtable summary

    • C. Mahony
    • R. Currie
    • B. van de Water

    Guest Editorial 16 January 2018 Pages: 1015 - 1020