Adverse outcome pathway development from protein alkylation to liver fibrosis Tomislav HorvatBrigitte LandesmannMaurice Whelan Review Article Open access 19 August 2016 Pages: 1523 - 1543
Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD) Salamah Mohammad AlwahshRolf Gebhardt Review Article 19 December 2016 Pages: 1545 - 1563
A systematic review of possible serious adverse health effects of nicotine replacement therapy Peter N. LeeMarc W. Fariss Review Article Open access 03 October 2016 Pages: 1565 - 1594
Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope Arathi KizhedathSimon WilkinsonJarka Glassey Review Article Open access 20 October 2016 Pages: 1595 - 1612
New developments and directions in the clinical application of the echinocandins C. C. ChangM. A. SlavinS. C.-A. Chen Review Article 08 February 2017 Pages: 1613 - 1621
High bioavailability curcumin: an anti-inflammatory and neurosupportive bioactive nutrient for neurodegenerative diseases characterized by chronic neuroinflammation Faheem UllahAndy LiangGerald Münch Review Article 15 February 2017 Pages: 1623 - 1634
Selenium-binding protein 1: a sensitive urinary biomarker to detect heavy metal-induced nephrotoxicity Eui Kyung LeeYoung-Jun ShinHyung Sik Kim Inorganic Compounds 30 August 2016 Pages: 1635 - 1648
Influence of testosterone on phase II metabolism and availability of soy isoflavones in male Wistar rats Sebastian T. SoukupDennis R. MüllerSabine E. Kulling Toxicokinetics and Metabolism 14 October 2016 Pages: 1649 - 1661
The importance of protein binding for the in vitro–in vivo extrapolation (IVIVE)—example of ibuprofen, a highly protein-bound substance H. MielkeE. Di ConsiglioU. Gundert-Remy Toxicokinetics and Metabolism 21 October 2016 Pages: 1663 - 1670
A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis Aruo NanLijian ChenYiguo Jiang Toxicogenomics Open access 07 September 2016 Pages: 1671 - 1684
Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats June K. DunnickKeith R. ShockleyArun R. Pandiri Toxicogenomics 16 September 2016 Pages: 1685 - 1696
Identification of protein tyrosine phosphatase SHP-2 as a new target of perfluoroalkyl acids in HepG2 cells Yu YangQi-Yan LvYa-Qi Cai Molecular Toxicology 29 August 2016 Pages: 1697 - 1707
Acrolein increases macrophage atherogenicity in association with gut microbiota remodeling in atherosclerotic mice: protective role for the polyphenol-rich pomegranate juice Oren RomHila Korach-RechtmanMichael Aviram Molecular Toxicology 30 September 2016 Pages: 1709 - 1725
Bisphenol A suppresses glucocorticoid target gene (ENaCγ) expression via a novel ERβ/NF-κB/GR signalling pathway in lung epithelial cells Ayten HijaziHaiyan GuanKaiping Yang Molecular Toxicology 13 August 2016 Pages: 1727 - 1737
SHP-2 phosphatase controls aryl hydrocarbon receptor-mediated ER stress response in mast cells Hsueh-Chun WangYufeng ZhouShau-Ku Huang Molecular Toxicology 05 October 2016 Pages: 1739 - 1748
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity Salil N. PendseAlexandra MaertensPatrick D. McMullen Molecular Toxicology Open access 03 September 2016 Pages: 1749 - 1762
Strain differences in the proteome of dioxin-sensitive and dioxin-resistant mice treated with 2,3,7,8-tetrabromodibenzo-p-dioxin Hoa Thanh NguyenMaria Claret Lauan TsuchiyaHisato Iwata Molecular Toxicology 07 September 2016 Pages: 1763 - 1782
Understanding chemical allergen potency: role of NLRP12 and Blimp-1 in the induction of IL-18 in human keratinocytes Angela PapaleElena KummerEmanuela Corsini Immunotoxicology 01 September 2016 Pages: 1783 - 1794
Exposures to the environmental toxicants pentachlorophenol (PCP) and dichlorodiphenyltrichloroethane (DDT) modify secretion of interleukin 1-beta (IL-1β) from human immune cells Tamara J. MartinMargaret M. Whalen Immunotoxicology 03 September 2016 Pages: 1795 - 1808
Comparison of biological effects with albumin adducts of 4,4′-methylenediphenyl diisocyanate in workers Gabriele SabbioniLakshiminiranjan Reddy VanimireddyDavid I. Bernstein Immunotoxicology 16 September 2016 Pages: 1809 - 1814
Self-assembled 3D spheroids and hollow-fibre bioreactors improve MSC-derived hepatocyte-like cell maturation in vitro Madalena CiprianoNora FreyerJoana P. Miranda In vitro Systems 02 September 2016 Pages: 1815 - 1832
Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature Thomas EfferthUrsula SchöttlerFrank A. Giordano Organ Toxicity and Mechanisms 12 August 2016 Pages: 1833 - 1846
Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells Mohammed QaisiyaCristina BrischettoCristina Bellarosa Organ Toxicity and Mechanisms 30 August 2016 Pages: 1847 - 1858
In vivo cardiomyocyte response to YTX- and AZA-1-induced damage: autophagy versus apoptosis Sara F. FerreiroNatalia VilariñoLuis M. Botana Organ Toxicity and Mechanisms 05 October 2016 Pages: 1859 - 1870
Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy A. Reis-MendesA. S. GomesV. M. Costa Organ Toxicity and Mechanisms 14 September 2016 Pages: 1871 - 1890
Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication Melissa FariaEva PratsDemetrio Raldúa Organ Toxicity and Mechanisms Open access 21 September 2016 Pages: 1891 - 1901
Effect of natural uranium on the UMR-106 osteoblastic cell line: impairment of the autophagic process as an underlying mechanism of uranium toxicity Valérie Pierrefite-CarleSabine Santucci-DarmaninGeorges F. Carle Organ Toxicity and Mechanisms 01 September 2016 Pages: 1903 - 1914
Dioxin-like rather than non-dioxin-like PCBs promote the development of endometriosis through stimulation of endocrine–inflammation interactions Qiansheng HuangYajie ChenSijun Dong Organ Toxicity and Mechanisms 23 September 2016 Pages: 1915 - 1924
TLR4-mediated inflammation is a key pathogenic event leading to kidney damage and fibrosis in cyclosporine nephrotoxicity Cristian González-GuerreroPablo Cannata-OrtizAdrián M. Ramos Organ Toxicity and Mechanisms 01 September 2016 Pages: 1925 - 1939
Investigations of putative reproductive toxicity of low-dose exposures to vinclozolin in Wistar rats Burkhard FlickSteffen SchneiderBennard van Ravenzwaay Reproductive Toxicology 09 September 2016 Pages: 1941 - 1956
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone Volker M. ArltWalter MeinlHeinz H. Schmeiser Genotoxicity and Carcinogenicity Open access 24 August 2016 Pages: 1957 - 1975
Variability of control data and relevance of observed group differences in five oral toxicity studies with genetically modified maize MON810 in rats Kerstin SchmidtJörg SchmidtkePablo Steinberg Biologics Open access 11 October 2016 Pages: 1977 - 2006
Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase Katharina JarolimGiorgia Del FaveroDoris Marko Biologics Open access 28 September 2016 Pages: 2007 - 2016
Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro Martin R. SchmuckThomas TemmeEllen Fritsche Protocols 08 October 2016 Pages: 2017 - 2028
