1. Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes

   • Thomas L. Goldsworthy
   • Thomas M. Monticello
   • Byron E. Butterworth

   Original Investigations Pages: 1 - 9

2. Epithelial binding of 1,1,2,2-tetrachloroethane in the respiratory and upper alimentary tract

   • Catarina Eriksson
   • Eva B. Brittebo

   Original Investigations Pages: 10 - 14

3. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo

   • K. J. Van den Berg
   • J. A. G. M. van Raaij
   • W. R. F. Notten

   Original Investigations Pages: 15 - 19

4. Cadmium/zinc-metallothionein induces DNA strand breaks in vitro

   • Thomas Müller
   • Rainer Schuckelt
   • Lothar Jaenicke

   Original Investigations Pages: 20 - 26

5. Reproductive toxicity and toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin

   • Ibrahim Chahoud
   • Ralf Krowke
   • Diether Neubert

   Original Investigations Pages: 27 - 31

6. Cyclophosphamide metabolism in the primary immune organs of the chick: Assays of drug activation, P450 expression, and aldehyde dehydrogenase

   • Rita R. Misra
   • Nancy A. Lorr
   • Stephen E. Bloom

   Original Investigations Pages: 32 - 38

7. Kinetic studies on toluene metabolism in ethanol- and phenobarbital-induced rat liver microsomes in vitro

   • Rui-Sheng Wang
   • Tamie Nakajima

   Original Investigations Pages: 39 - 44

8. Effects of acetone administration on cytochrome P-450-dependent monooxygenases in hamster liver, kidney, and lung

   • Tzuu-Huei Ueng
   • Jen-Ning Tsai
   • F. Peter Guengerich

   Original Investigations Pages: 45 - 51

9. Identification of urinary metabolites in rats treated withp-chloronitrobenzene

   • Toshiaki Yoshida
   • Katashi Andoh
   • Takeo Tabuchi

   Original Investigations Pages: 52 - 58

10. Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man

    • P. E. Kreuzer
    • W. Kessler
    • J. G. Filser

    Original Investigations Pages: 59 - 67

11. Nicotine metabolism in isolated perfused lung and liver of phenobarbital- and benzoflavone-treated rats

    • Heidi Foth
    • Helmut Looschen
    • Georg F. Kahl

    Original Investigations Pages: 68 - 72

12. Vascular toxicity in dogs associated with overdoses of a novel benzodiazepine receptor partial agonist

    • Bernhard Schlaeppi
    • Gaetano Roncari
    • Peter Zahm

    Original Investigations Pages: 73 - 80