Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing Ji-Eun SeoYuan LeXiaoqing Guo Genotoxicity and Carcinogenicity Open access 07 April 2024 Pages: 1919 - 1935
Human metabolism of four synthetic benzimidazole opioids: isotonitazene, metonitazene, etodesnitazene, and metodesnitazene Omayema TaoussiDiletta BerardinelliJeremy Carlier Toxicokinetics and Metabolism Open access 06 April 2024
Dissecting the networks underlying diverse brain disorders after prenatal glucocorticoid overexposure Baixiu ZhengYanrong ZhengZhong Chen Review Article 06 April 2024
Muller and mutations: mouse study of George Snell (a postdoc of Muller) fails to confirm Muller’s fruit fly findings, and Muller fails to cite Snell’s findings Edward J. CalabresePaul B. Selby Letter to the Editor, News and Views 04 April 2024 Pages: 1953 - 1963
The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice Yanwei WangJingru QiuHaiyan Lou Molecular Toxicology 04 April 2024 Pages: 1781 - 1794
Validation of putative biomarkers of furan exposure through quantitative analysis of furan metabolites in urine of F344 rats exposed to stable isotope labeled furan C. KalischM. ReiterA. Mally Analytical Toxicology Open access 04 April 2024 Pages: 1741 - 1756
Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food Gerhard EisenbrandAndrea BuettnerJan G. Hengstler Editorial Open access 04 April 2024 Pages: 1573 - 1580
Intestinal carcinogenicity screening of environmental pollutants using organoid-based cell transformation assay Ziwei WangShen ChenWen Chen Genotoxicity and Carcinogenicity 02 April 2024 Pages: 1937 - 1951
Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish Liao-Chen ChenHwei-Hsien ChenMing-Huan Chan Organ Toxicity and Mechanisms 02 April 2024 Pages: 1827 - 1842
Female offspring of mice perinatally exposed to benzophenone-3 showed early subfertility linked to a poor oocyte stockpile Valentina GallianiJulián Elías AbudHoracio Adolfo Rodríguez Reproductive Toxicology 30 March 2024 Pages: 1909 - 1918
Effects of the nerve agent VX on hiPSC-derived motor neurons Catherine SchaefersWolfgang SchmeißerAnnette Schmidt Organ Toxicity and Mechanisms Open access 30 March 2024 Pages: 1859 - 1875
A problem formulation framework for the application of in silico toxicology methods in chemical risk assessment Jerry AcharMark T. D. CroninGunilla Öberg Regulatory Toxicology Open access 30 March 2024 Pages: 1727 - 1740
Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy Deyuan NingJinfang XueGuobing Chen Review Article 30 March 2024 Pages: 1705 - 1716
The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice Olamide B. AdelusiJephte Y. AkakpoHartmut Jaeschke Organ Toxicity and Mechanisms 29 March 2024 Pages: 1843 - 1858
Review: myogenic and muscle toxicity targets of environmental methylmercury exposure Lok Ming TamMatthew D. Rand Review Article 28 March 2024 Pages: 1645 - 1658
Ochratoxin A induces hepatic and renal toxicity in mice through increased oxidative stress, mitochondrial damage, and multiple cell death mechanisms Youlim SonHyun Jung LeeHwa-Young Kim Biologics 28 March 2024
The interactions of subcellular organelles in pulmonary fibrosis induced by carbon black nanoparticles: a comprehensive review Lei BaoQingping LiuRong Zhang Review Article 27 March 2024 Pages: 1629 - 1643
Integration of apaQTL and eQTL analysis reveals novel SNPs associated with occupational pulmonary fibrosis risk Zhenyu LiWendi ZhangMinjie Chu Toxicogenomics and Omics Technologies 27 March 2024
PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man Anja LehmannIna GeburekChristoph Hethey Toxicokinetics and Metabolism Open access 25 March 2024 Pages: 1757 - 1769
Multi-organ developmental toxicity and its characteristics in fetal mice induced by dexamethasone at different doses, stages, and courses during pregnancy Xiaoqi ZhaoHao XiaoHui Wang Reproductive Toxicology 24 March 2024 Pages: 1891 - 1908
Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes Slobodan P. RendicF. Peter Guengerich Review Article 23 March 2024 Pages: 1581 - 1628
Role of the complement system in kidney cell death induced by Loxosceles venom Sphingomyelinases D Cinthya Kimori OkamotoCarmen W. van den BergDenise V. Tambourgi Biologics 18 March 2024 Pages: 1561 - 1572
CircRNA: a rising therapeutic strategy for lung injury induced by pulmonary toxicants Cai LiaoZhen-Wei HeYun Wang Review Article 18 March 2024 Pages: 1297 - 1310
Cytogenotoxicity and inflammatory response in liver of rats exposed to different doses of cannabis nano emulsions Thiago Guedes PintoBarbara dos Anjos RosarioDaniel Araki Ribeiro Organ Toxicity and Mechanisms 17 March 2024 Pages: 1877 - 1890
The estimation of acute oral toxicity (LD50) of G-series organophosphorus-based chemical warfare agents using quantitative and qualitative toxicology in silico methods Maciej NogaAgata MichalskaKamil Jurowski In silico 17 March 2024 Pages: 1809 - 1825
Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation Xin-Man HuYan-Yao HouChun-Zhi Ai In silico 16 March 2024 Pages: 1457 - 1467
Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration Hengyang ShenYang ChenZan Fu Genotoxicity and Carcinogenicity 14 March 2024 Pages: 1499 - 1513
Combined use of multiparametric high-content-screening and in vitro circadian reporter assays in neurotoxicity evaluation Youngil ParkHwan-Goo KangJae-Hak Park Organ Toxicity and Mechanisms Open access 14 March 2024 Pages: 1485 - 1498
Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route data for exposure assessment by human biomonitoring Katharina E. EbertPeter GriemDaniel Bury Toxicokinetics and Metabolism Open access 14 March 2024 Pages: 1383 - 1398
Elevated aerobic glycolysis driven by p62-mTOR axis promotes arsenic-induced oncogenic phenotypes in human mammary epithelial cells Yongfang LiJiao LiuYuanyuan Xu Inorganic Compounds 14 March 2024 Pages: 1369 - 1381
Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants Klaudia JomovaSuliman Y. AlomarMarian Valko Review Article Open access 14 March 2024 Pages: 1323 - 1367
Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency Matthias HerzlerJaleh AbediniNicole Kleinstreuer Review Article Open access 14 March 2024 Pages: 1253 - 1269
Recent advances and current challenges of new approach methodologies in developmental and adult neurotoxicity testing Melania Maria SerafiniSara SepehriTanima SenGupta Review Article Open access 13 March 2024 Pages: 1271 - 1295
Involvement of per- and polyfluoroalkyl compounds in tumor development Maija PesonenKirsi Vähäkangas Review Article Open access 13 March 2024 Pages: 1241 - 1252
Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats Reham HassanZaynab HoblossAhmed Ghallab Organ Toxicity and Mechanisms 11 March 2024 Pages: 1533 - 1542
Circular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells and mice models Yong ZhuXiaoxiao MengRuilan Wang Molecular Toxicology Open access 09 March 2024 Pages: 1399 - 1413
Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms Di WuKejia ZhangChunjie Huang Review Article 09 March 2024 Pages: 1685 - 1703
A-series agent A-234: initial in vitro and in vivo characterization Martina HrabinovaJaroslav PejchalDaniel Jun Molecular Toxicology Open access 06 March 2024 Pages: 1135 - 1149
The acute toxicity of Novichok's degradation products using quantitative and qualitative toxicology in silico methods Maciej NogaAgata MichalskaKamil Jurowski In Silico 05 March 2024 Pages: 1469 - 1483
YES1 as a potential target to overcome drug resistance in EGFR-deregulated non-small cell lung cancer Eunjin KookJungYeol LeeDo-Hee Kim Molecular Toxicology 05 March 2024 Pages: 1437 - 1455
In vitro and in vivo protective potential of quercetin-3-glucuronide against lipopolysaccharide-induced pulmonary injury through dual activation of nuclear factor-erythroid 2 related factor 2 and autophagy Pei-Rong YuChiao-Yun TsengHui-Hsuan Lin Molecular Toxicology 04 March 2024 Pages: 1415 - 1436
Genetic variants in m5C modification genes are associated with survival of patients with HBV-related hepatocellular carcinoma Bowen ChenMoqin QiuHongping Yu Toxicogenomics and Omics Technologies 04 March 2024 Pages: 1125 - 1134
Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats Reham HassanAndrea GerdemannAhmed Ghallab Toxicokinetics and Metabolism 04 March 2024 Pages: 1081 - 1093
Toxicity of particles derived from combustion of Ethiopian traditional biomass fuels in human bronchial and macrophage-like cells Sarah McCarrickMathilde N. DelavalAnda R. Gliga Organ Toxicity and Mechanisms Open access 01 March 2024 Pages: 1515 - 1532
Effect of cell treatment procedures on in vitro genotoxicity assessment Cynthia RecoulesGladys MireyMarc Audebert Genotoxicity and Carcinogenicity 01 March 2024 Pages: 1225 - 1236
Excavatolide C/cisplatin combination induces antiproliferation and drives apoptosis and DNA damage in bladder cancer cells Tsu-Ming ChienChe-Wei YangHsueh-Wei Chang Genotoxicity and Carcinogenicity 29 February 2024 Pages: 1543 - 1560
Effects of marine biotoxins on drug-metabolizing cytochrome P450 enzymes and their regulation in mammalian cells Leonie T. D. WürgerJimmy AlarcanAlbert Braeuning Review Article Open access 28 February 2024 Pages: 1311 - 1322
ATF4 in cellular stress, ferroptosis, and cancer Hu TangRui KangDaolin Tang Review Article 21 February 2024 Pages: 1025 - 1041
Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach Ana Margarida AraújoSandra I. MarquesJoão Pedro Silva Molecular Toxicology Open access 18 February 2024 Pages: 1151 - 1161
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice Mark R. ViantE. AmstaldenH. Kamp Toxicogenomics and Omics Technologies Open access 18 February 2024 Pages: 1111 - 1123