1. Introduction to the symposium “What is the importance of chronobiology in toxicology and pharmacology?”

   • H. Frohberg

   OriginalPaper Pages: 181 - 184

2. Time — A key in experimental and practical medicine

   • H. v. Mayersbach

   OriginalPaper Pages: 185 - 216

3. Circadian fluctuations in the activity of DNA-dependent RNA polymerases I and II in the nuclei isolated from mouse tissues and the significance for pharmacological and toxicological studies on transcription

   • Diether Neubert
   • Margret Rautenberg

   OriginalPaper Pages: 217 - 234

4. Fütterungs-Rhythmen und die circadianen Variationen der Zellproliferation bei pharmakologisch induziertem Leberwachstum

   • R. Schulte-Hermann

   OriginalPaper Pages: 235 - 245

5. Possible influences of circadian rhythms in experimental carcinogenesis

   • Ole Didrik Laerum

   OriginalPaper Pages: 247 - 254

6. Genetic and hormonal regulation of steroid hydroxylases and drug metabolizing enzymes in rat liver

   • Jacques E. Gielen
   • Jacques Van Cantfort
   • Pierre Kremers

   OriginalPaper Pages: 255 - 266

7. The circadian rhythm of synthesis and catabolism of cholesterol

   • Dieter Mayer

   OriginalPaper Pages: 267 - 276

8. The manipulation of circadian rhythms

   • Karel M. H. Philippens

   OriginalPaper Pages: 277 - 303

9. Circadian rhythm of the renin-angiotensin-aldosterone system in the rat

   • M. Hilfenhaus

   OriginalPaper Pages: 305 - 316

10. Circadian influences on clinical values in man

    • G. Steinbach
    • M. Hilfenhaus
    • W. Poesche

    OriginalPaper Pages: 317 - 325

11. New aspects of human chronopharmacology

    • Alain Reinberg

    OriginalPaper Pages: 327 - 339