Volume 12, issue 1, December 2022
212 articles in this issue
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SPOP inhibits BRAF-dependent tumorigenesis through promoting non-degradative ubiquitination of BRAF
Authors (first, second and last of 11)
- Kai Feng
- Qing Shi
- Chenji Wang
- Content type: Research
- Open Access
- Published: 30 December 2022
- Article: 211
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Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase
Authors (first, second and last of 10)
- Yue Guo
- Donghao Guo
- Hui Zhao
- Content type: Research
- Open Access
- Published: 30 December 2022
- Article: 210
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A new thinking: deciphering the aberrance and clinical implication of copper-death signatures in clear cell renal cell carcinoma
Authors (first, second and last of 10)
- Aimin Jiang
- Peng Luo
- Chen Cai
- Content type: Research
- Open Access
- Published: 29 December 2022
- Article: 209
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A novel promising diagnosis model for colorectal advanced adenoma and carcinoma based on the progressive gut microbiota gene biomarkers
Authors (first, second and last of 16)
- Junfeng Xu
- Zhijun Zheng
- Peng Jin
- Content type: Research
- Open Access
- Published: 26 December 2022
- Article: 208
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RNA N6-methyladenosine modification mediates downregulation of NR4A1 to facilitate malignancy of cervical cancer
Authors (first, second and last of 14)
- Tao Yu
- Fuxia Wu
- Yankun Liu
- Content type: Research
- Open Access
- Published: 25 December 2022
- Article: 207
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Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice
Authors (first, second and last of 6)
- Huazhong Xie
- Pengfei Qiang
- Min Li
- Content type: Research
- Open Access
- Published: 21 December 2022
- Article: 206
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Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes
Authors (first, second and last of 9)
- Ying Zhang
- Bingfeng Fan
- Baozeng Xu
- Content type: Research
- Open Access
- Published: 20 December 2022
- Article: 205
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FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagy
Authors (first, second and last of 10)
- Teng Sun
- Yu Han
- Jian-Xun Wang
- Content type: Research
- Open Access
- Published: 19 December 2022
- Article: 204
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VHL-recruiting PROTAC attenuates renal fibrosis and preserves renal function via simultaneous degradation of Smad3 and stabilization of HIF-2α
Authors (first, second and last of 9)
- Jiayi Yang
- Yuyi Ruan
- Xin Wang
- Content type: Research
- Open Access
- Published: 19 December 2022
- Article: 203
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Overview of the meningeal lymphatic vessels in aging and central nervous system disorders
Authors (first, second and last of 6)
- Huimin Jiang
- Huimin Wei
- Xunming Ji
- Content type: Review
- Open Access
- Published: 17 December 2022
- Article: 202
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Correction: Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease
Authors (first, second and last of 22)
- Qian Zhu
- Min Qin
- Shilong Zhong
- Content type: Correction
- Open Access
- Published: 16 December 2022
- Article: 201
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Distinct mechanisms mediating therapy-induced cellular senescence in prostate cancer
Authors (first, second and last of 4)
- Julia Kallenbach
- Golnaz Atri Roozbahani
- Aria Baniahmad
- Content type: Review
- Open Access
- Published: 15 December 2022
- Article: 200
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Male guanine-rich RNA sequence binding factor 1 knockout mice (Grsf1−/−) gain less body weight during adolescence and adulthood
Authors (first, second and last of 7)
- Bernhard Dumoulin
- Dagmar Heydeck
- Hartmut Kuhn
- Content type: Research
- Open Access
- Published: 09 December 2022
- Article: 199
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Hif-2α regulates lipid metabolism in alcoholic fatty liver disease through mitophagy
Authors (first, second and last of 9)
- Mei-fei Wu
- Guo-dong Zhang
- Lei Zhang
- Content type: Research
- Open Access
- Published: 07 December 2022
- Article: 198
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Activation of Piezo1 downregulates renin in juxtaglomerular cells and contributes to blood pressure homeostasis
Authors (first, second and last of 5)
- Xiaoqiang Yang
- Honghui Zeng
- Yiming Zhou
- Content type: Research
- Open Access
- Published: 05 December 2022
- Article: 197
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Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury
Authors (first, second and last of 7)
- Tu Hu
- Shuhan Meng
- Dan Chen
- Content type: Research
- Open Access
- Published: 05 December 2022
- Article: 196
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Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway
Authors (first, second and last of 11)
- Zewei Zhao
- Huijuan Wang
- Xiangqian Zheng
- Content type: Research
- Open Access
- Published: 05 December 2022
- Article: 195
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PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders
Authors (first, second and last of 9)
- Dantong Shang
- Tian Lan
- Rongjia Zhou
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 194
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In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer
Authors (first, second and last of 11)
- Lu Liu
- Yuxi Lei
- Liang Chen
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 193
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MicroRNA-378a-3p prevents initiation and growth of colorectal cancer by fine tuning polyamine synthesis
Authors (first, second and last of 4)
- Ningning Liu
- Tianpeng Zhang
- Guisheng Song
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 192
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Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone
Authors (first, second and last of 7)
- Yan Zeng
- Manuel A. Riquelme
- Jean X. Jiang
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 191
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A synthetic pregnenolone analog promotes microtubule dynamics and neural development
Authors (first, second and last of 6)
- Viktoryia Kolas
- Jose Sandino A. Bandonil
- Bon-chu Chung
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 190
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Proteomic signatures of schizophrenia-sourced iPSC-derived neural cells and brain organoids are similar to patients' postmortem brains
Authors (first, second and last of 8)
- Juliana Minardi Nascimento
- Verônica M. Saia-Cereda
- Daniel Martins-de-Souza
- Content type: Research
- Open Access
- Published: 01 December 2022
- Article: 189
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Defb19 regulates the migration of germ cell and is involved in male fertility
Authors (first, second and last of 6)
- Jing Jin
- Xiaofeng Li
- Kin Lam Fok
- Content type: Letter to the Editor
- Open Access
- Published: 22 November 2022
- Article: 188
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The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity
Authors
- Qianhui Li
- Feng Chen
- Fei Wang
- Content type: Review
- Open Access
- Published: 22 November 2022
- Article: 187
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DNA methylation in diabetic retinopathy: pathogenetic role and potential therapeutic targets
Authors (first, second and last of 8)
- Chunyang Cai
- Chunren Meng
- Qinghua Qiu
- Content type: Review
- Open Access
- Published: 17 November 2022
- Article: 186
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Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis
Authors (first, second and last of 9)
- Changcheng Guo
- Yin Sun
- Chawnshang Chang
- Content type: Research
- Open Access
- Published: 17 November 2022
- Article: 185
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Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis
Authors
- Kyung-Yil Lee
- Content type: Review
- Open Access
- Published: 16 November 2022
- Article: 184
This is part of 1 collection: -
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A
Authors (first, second and last of 13)
- Liang Zhao
- Huizhao Su
- Bo Tang
- Content type: Research
- Open Access
- Published: 12 November 2022
- Article: 183
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An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation
Authors (first, second and last of 6)
- Gabriella Ferretti
- Alessia Romano
- Carmela Matrone
- Content type: Research
- Open Access
- Published: 08 November 2022
- Article: 182
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The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate
Authors (first, second and last of 11)
- Zili Li
- Fang Fang
- Honggang Li
- Content type: Research
- Open Access
- Published: 04 November 2022
- Article: 181
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Salidroside reduces neuropathology in Alzheimer’s disease models by targeting NRF2/SIRT3 pathway
Authors (first, second and last of 16)
- Yuyuan Yao
- Zhichu Ren
- Jian Sima
- Content type: Research
- Open Access
- Published: 04 November 2022
- Article: 180
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Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps
Authors (first, second and last of 4)
- Kaiyuan Zhu
- Noor Kazim
- Andrew Yen
- Content type: Research
- Open Access
- Published: 03 November 2022
- Article: 179
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Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake
Authors (first, second and last of 8)
- Ishnoor Singh
- Le Wang
- Zhiping P. Pang
- Content type: Research
- Open Access
- Published: 29 October 2022
- Article: 178
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Wasteosomes (corpora amylacea) of human brain can be phagocytosed and digested by macrophages
Authors (first, second and last of 11)
- Marta Riba
- Joan Campo-Sabariz
- Carme PelegrÃ
- Content type: Research
- Open Access
- Published: 28 October 2022
- Article: 177
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Tumour-associated macrophages enhance breast cancer malignancy via inducing ZEB1-mediated DNMT1 transcriptional activation
Authors (first, second and last of 10)
- Zhongwei Li
- Pengfei Wang
- Jin Bai
- Content type: Research
- Open Access
- Published: 22 October 2022
- Article: 176
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Long-term maintenance of human endometrial epithelial stem cells and their therapeutic effects on intrauterine adhesion
Authors (first, second and last of 11)
- Wen He
- Xuejing Zhu
- Xiaoxi Sun
- Content type: Research
- Open Access
- Published: 18 October 2022
- Article: 175
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Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium
Authors (first, second and last of 10)
- Yapei Yuan
- Huan Chen
- Fan Fan Hou
- Content type: Research
- Open Access
- Published: 15 October 2022
- Article: 174
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Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease
Authors (first, second and last of 22)
- Qian Zhu
- Min Qin
- Shilong Zhong
- Content type: Research
- Open Access
- Published: 14 October 2022
- Article: 173
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RNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression
Authors (first, second and last of 17)
- Yanyan Wang
- Yun-Ling Tai
- Huiping Zhou
- Content type: Research
- Open Access
- Published: 12 October 2022
- Article: 172
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CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation
Authors (first, second and last of 8)
- Mahan Si
- Yujia Song
- Xinfeng Yu
- Content type: Research
- Open Access
- Published: 09 October 2022
- Article: 171
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SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis
Authors (first, second and last of 21)
- Meng Yu
- Jonathan C. Bean
- Chunmei Wang
- Content type: Research
- Open Access
- Published: 09 October 2022
- Article: 170
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Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity
Authors (first, second and last of 13)
- Hongsheng Wang
- Xinmeng Jin
- Wei Sun
- Content type: Research
- Open Access
- Published: 08 October 2022
- Article: 169
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Characterization of placental and decidual cell development in early pregnancy loss by single-cell RNA sequencing
Authors (first, second and last of 11)
- Yuhua Zheng
- Jing Pan
- Nanbert Zhong
- Content type: Research
- Open Access
- Published: 08 October 2022
- Article: 168
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Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype
Authors (first, second and last of 11)
- Jiahui Long
- Xia Luo
- Min Li
- Content type: Research
- Open Access
- Published: 08 October 2022
- Article: 167
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Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene
Authors (first, second and last of 8)
- Hui Tian
- Yanwen Jiao
- Weiming Tian
- Content type: Research
- Open Access
- Published: 07 October 2022
- Article: 166
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Revisiting potential value of antitumor drugs in the treatment of COVID-19
Authors (first, second and last of 4)
- Wenfang Zheng
- Zekun Zeng
- Peng Hou
- Content type: Review
- Open Access
- Published: 01 October 2022
- Article: 165
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Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation
Authors (first, second and last of 11)
- Dongting Yao
- Jiuru Zhao
- Zhiwei Liu
- Content type: Research
- Open Access
- Published: 01 October 2022
- Article: 164
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YAP1 protects against septic liver injury via ferroptosis resistance
Authors (first, second and last of 6)
- Jin Wang
- Qian Zhu
- Xinyi Li
- Content type: Research
- Open Access
- Published: 01 October 2022
- Article: 163