1. In memoriam Professor Achilles Benakis

   • Momir Mikov

   EditorialNotes Pages: 131 - 132

2. Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT®) following oral administration in African malaria patients

   • V. Sinou
   • L. Tshilolo Muepu Maladca
   • A. Benakis

   OriginalPaper Pages: 133 - 142

3. Changes of lidocaine levels in rat serum and tissue under stress and hyperlipidaemic diets

   • Dimitrios Karakitsos
   • Andreas Karabinis
   • Antonia Kotsiou

   OriginalPaper Pages: 143 - 146

4. Genetic CYP2C19 polymorphism dependent non-responders to clopidogrel therapy — Does structural design, dosing and induction strategies have a role to play?

   • Nuggehally R. Srinivas

   OriginalPaper Pages: 147 - 150

5. Effect of phytomedicines, AM-1, niprisan® and nifadin on the pharmacokinetics of chloroquine in rats

   • K. B. Mustapha
   • M. T. Bakare-Odunola
   • U. S. Inyan

   OriginalPaper Pages: 151 - 155

6. Pharmacokinetics and bioequivalence studiesof cefteram pivoxil in healthy Chinese volunteers

   • Fangmi Wei
   • Rong Zhu
   • Qin Hu

   OriginalPaper Pages: 157 - 162

7. Effects of simvastatinon the pharmacokinetics of verapamil and its main metabolite, norverapamil, in rats

   • Dong-Hyun Choi
   • Cheng Li
   • Jun-Shik Choi

   OriginalPaper Pages: 163 - 168

8. Urinary elimination kinetics of pyrimethamine

   • J. B. Mouankie
   • W. Senczuk
   • E. Florek

   OriginalPaper Pages: 169 - 172

9. Kinetics of pyrimethamine in young and adult rats on a standard diet and on a low-protein diet

   • J. B. Mouankie
   • W. Senczuk
   • E. Florek

   OriginalPaper Pages: 173 - 176

10. Development and validation of a sensitive LC-MS method for the determination of Promethazine hydrochloride in human plasma and urine

    • Ping Liu
    • Sun Liang
    • Rui-Chen Guo

    OriginalPaper Pages: 177 - 184

11. Development and validation of a sensitive LC-MS method for the determination of tramadol in human plasma and urine

    • Ping Liu
    • Sun Liang
    • Rui-Chen Guo

    OriginalPaper Pages: 185 - 192

12. Pharmacokinetics, safety and tolerance of single- and multiple-dose of a novel compound tramadol hydrochloride injection (35 mg tramadol hydrochloride, 45 mgl promethazine hydrochloride) in Chinese healthy subjects

    • Ping Liu
    • Sun Liang
    • Rui-Chen Guo

    OriginalPaper Pages: 193 - 200

13. Change in blood tacrolimus concentration by fluctuation of renal function in a bone marrow transplant patient

    • Masaki Sumi
    • Hiroki Konishi
    • Akira Yamaji

    OriginalPaper Pages: 201 - 204

14. Construction of expression system of rabbit aldehyde oxidase cDNA for the clarification of species differences

    • Ping Liu
    • Sun Liang
    • Rui-Chen Guo

    OriginalPaper Pages: 205 - 211

15. The toxicity of aconitine, emodin on ICC cell and the anagonist effect of the compatibility

    • Peng Cheng
    • Wang Lan
    • Pan Yuan

    OriginalPaper Pages: 213 - 220

16. Comparative single- and multiple-dose pharmacokinetics of rosuvastatin following oral administration in Chinese volunteers

    • Yunxia Li
    • Xuehua Jiang
    • Qian Jiang

    OriginalPaper Pages: 221 - 227

17. Clonidine changes lidocaine free concentrations in rat myocardium without affecting heart function measured by echocardiography

    • E. Tigka
    • A Kotsiou
    • C. Tesse-Romatis

    OriginalPaper Pages: 229 - 232