1. Editorial

   EditorialNotes Pages: 172 - 172

2. Design of histamine H₃-receptor agonists and antagonists

   • Walter Schunack
   • Holger Stark

   OriginalPaper Pages: 173 - 178

3. Medicinal chemistry of muscarinic agonists for the treatment of dementia disorders

   • E. Cereda
   • A. Brambilla
   • A. Sagrada

   OriginalPaper Pages: 179 - 183

4. The design of potential antidiabetic drugs: experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase

   • N. G. Oikonomakos
   • M. Kontou
   • K. R. Acharya

   OriginalPaper Pages: 185 - 192

5. Design of drugs through a consideration of drug metabolism and pharmacokinetics

   • Dennis A. Smith

   OriginalPaper Pages: 193 - 199

6. The metabolism of drugs by the gut flora

   • M. Mikov

   OriginalPaper Pages: 201 - 207

7. The metabolism of alicyclic amines to reactive iminium ion intermediates

   • J. W. Gorrod
   • G. Aislaitner

   OriginalPaper Pages: 209 - 217

8. Molecular toxicology of peroxisome proliferators

   • Fiona McNae
   • Raj Sharma
   • G. Gordon Gibson

   OriginalPaper Pages: 219 - 223

9. The use of computers in the safety evaluation of drugs and other chemicals

   • Costas Ioannides
   • David F. V. Lewis
   • Dennis V. Parke

   OriginalPaper Pages: 225 - 233

10. Capillary electrophoresis and Capillary Electrophoresis-mass spectrometry in drug and metabolite analysis

    • Stephen Naylor
    • Andy J. Tomlinson
    • John W. Gorrod

    OriginalPaper Pages: 235 - 240

11. Enantiospecific analysis: Applications in bioanalysis and metabolism

    • A. J. Hutt
    • M. R. Hadley
    • S. C. Tan

    OriginalPaper Pages: 241 - 251

12. Drug targeting with nanoparticles

    • Jörg Kreuter

    OriginalPaper Pages: 253 - 256

13. Surfactant systems: Microemulsions and vesicles as vehicles for drug delivery

    • M Jayne Lawrence

    OriginalPaper Pages: 257 - 269

14. Bioequivalency evaluation by comparison ofin vitro dissolution andin vivo absorption using reference equations

    • A. Kayali

    OriginalPaper Pages: 271 - 277

15. Plasma levels and therapeutic response: The relevance to community pharmacy

    • Terry Maguire

    OriginalPaper Pages: 279 - 281

16. Are we doing too many animal biodisposition investigations before Phase I studies in man?

    • D. B. Campbell

    OriginalPaper Pages: 283 - 293