Volume 17, Issue 3

Neurotherapeutics is now archived and no longer receiving submissions with this publisher. All articles published in the journal during its time with Springer will remain fully searchable through our websites.

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July 2020

Aligning New Approaches to Accelerate the Development of Non‐opioid Analgesic Therapies

44 articles in this issue

Aligning New Approaches to Accelerate the Development of Non-opioid Analgesic Therapies
Christine N. Sang
William K. Schmidt
Editorial 14 October 2020 Pages: 765 - 769
Considerations in the Assessment of Clinical Benefit with a Focus on Pain: a Regulatory Perspective
Christopher O. St. Clair
Elektra J. Papadopoulos
Review 10 August 2020 Pages: 770 - 773
Emerging Clinical Technology: Application of Machine Learning to Chronic Pain Assessments Based on Emotional Body Maps
Pavel Goldstein
Yoni Ashar
Tor D. Wager
Review 07 August 2020 Pages: 774 - 783
Novel Analgesics with Peripheral Targets
Cosmin I. Ciotu
Michael J. M. Fischer
Review Open access 15 October 2020 Pages: 784 - 825
P2X3-Containing Receptors as Targets for the Treatment of Chronic Pain
Jeffrey L. Krajewski
Review 02 October 2020 Pages: 826 - 838
Central Nervous System Targets: Supraspinal Mechanisms of Analgesia
K. Bannister
A. H. Dickenson
Review Open access 22 July 2020 Pages: 839 - 845
Central Nervous System Targets: Glial Cell Mechanisms in Chronic Pain
Christopher R. Donnelly
Amanda S. Andriessen
Ru-Rong Ji
Review 20 August 2020 Pages: 846 - 860
Neuronal Adenylyl Cyclase Targeting Central Plasticity for the Treatment of Chronic Pain
Xu-Hui Li
Qi-Yu Chen
Min Zhuo
Review 15 September 2020 Pages: 861 - 873
Central Nervous System Targets: Inhibitory Interneurons in the Spinal Cord
David I Hughes
Andrew J Todd
Review Open access 07 October 2020 Pages: 874 - 885
Neuromodulation, Specialized Proresolving Mediators, and Resolution of Pain
Xueshu Tao
Michael S. Lee
Ru-Rong Ji
Review 21 July 2020 Pages: 886 - 899
Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain
Karen M. Wagner
Aldrin Gomes
Bruce D. Hammock
Review 01 September 2020 Pages: 900 - 916
Interactions Among lncRNAs/circRNAs, miRNAs, and mRNAs in Neuropathic Pain
Ge Song
Zheng Yang
Xueqiang Wang
Review 06 July 2020 Pages: 917 - 931
Critical NIH Resources to Advance Therapies for Pain: Preclinical Screening Program and Phase II Human Clinical Trial Network
Smriti Iyengar
Sarah A. Woller
Barbara I. Karp
Review Open access 02 September 2020 Pages: 932 - 934
Immunotherapies for Aging-Related Neurodegenerative Diseases—Emerging Perspectives and New Targets
Somin Kwon
Michiyo Iba
Eliezer Masliah
Current Perspectives 28 April 2020 Pages: 935 - 954
Treatment of Progressive Multifocal Leukoencephalopathy Using Immune Restoration
S. Richard Dunham
Robert Schmidt
David B. Clifford
Current Perspectives 12 March 2020 Pages: 955 - 965
The Nerve to Give BACE Inhibitors a Second Chance?
Robert H. Baloh
Commentary 08 June 2020 Pages: 966 - 967
The Rise and Fall of High-Dose Biotin to Treat Progressive Multiple Sclerosis
Carolyn H. Goldschmidt
Jeffrey A. Cohen
Commentary 05 August 2020 Pages: 968 - 970
Commentary: The Multiple Sclerosis Controversy: Is It Escalation or Induction High Efficacy?
Patricia K. Coyle
Commentary 02 June 2020 Pages: 971 - 972
Pharmacological BACE Inhibition Improves Axonal Regeneration in Nerve Injury and Disease Models
Carolyn Tallon
Katherine L. Marshall
Mohamed. H. Farah
Original Article 31 March 2020 Pages: 973 - 988
Relapses During High-Dose Biotin Treatment in Progressive Multiple Sclerosis: a Case-Crossover and Propensity Score-Adjusted Prospective Cohort
Pierre Branger
Jean-Jacques Parienti
Gilles Defer
Original Article 15 June 2020 Pages: 989 - 993
Induction Versus Escalation in Multiple Sclerosis: A 10-Year Real World Study
Luca Prosperini
Chiara Rosa Mancinelli
Claudio Gasperini
Original Article 31 March 2020 Pages: 994 - 1004
The Use of the Selective Imidazoline I₁ Receptor Agonist Carbophenyline as a Strategy for Neuropathic Pain Relief: Preclinical Evaluation in a Mouse Model of Oxaliplatin-Induced Neurotoxicity
Laura Micheli
Lorenzo Di Cesare Mannelli
Carla Ghelardini
Original Article 22 June 2020 Pages: 1005 - 1015
Prolonged Use of NMDAR Antagonist Develops Analgesic Tolerance in Neuropathic Pain via Nitric Oxide Reduction-Induced GABAergic Disinhibition
Jun Li
Lin Zhang
Dong-Ya Zhu
Original Article 06 July 2020 Pages: 1016 - 1030
RETRACTED ARTICLE: Mechanisms Involved in Superiority of Angiotensin Receptor Blockade over ACE Inhibition in Attenuating Neuropathic Pain Induced in Rats
Nora Hegazy
Samar Rezq
Ahmed Fahmy
Original Article 17 August 2020 Pages: 1031 - 1047
Therapeutic Role of Neuregulin 1 Type III in SOD1-Linked Amyotrophic Lateral Sclerosis
Guillem Mòdol-Caballero
Belén García-Lareu
Mireia Herrando-Grabulosa
Original Article 21 January 2020 Pages: 1048 - 1060
The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies
Julia Marschallinger
Barbara Altendorfer
Ludwig Aigner
Original Article Open access 18 February 2020 Pages: 1061 - 1074
Wake-Promoting and EEG Spectral Effects of Modafinil After Acute or Chronic Administration in the R6/2 Mouse Model of Huntington’s Disease
Szilvia Vas
Jackie M. Casey
A. Jennifer Morton
Original Article Open access 15 April 2020 Pages: 1075 - 1086
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer’s Disease Pathogenesis in Cell and Animal Models
Hui Wei
Hui-liang Zhang
Rong Liu
Original Article 24 February 2020 Pages: 1087 - 1103
Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson’s Disease
Jing Zou
Yue Guo
Anding Xu
Original Article 31 March 2020 Pages: 1104 - 1119
DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats
Puneet K. Sharma
Lisa Wells
Ilse S. Pienaar
Original Article Open access 21 January 2020 Pages: 1120 - 1141
Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate
Karl E. Carlström
Praveen K. Chinthakindi
Katarina Johansson
Original Article Open access 11 May 2020 Pages: 1142 - 1152
Targeting Therapeutic Antibodies to the CNS: a Comparative Study of Intrathecal, Intravenous, and Subcutaneous Anti-Nogo A Antibody Treatment after Stroke in Rats
Anna-Sophia Wahl
Daphne Correa
Martin E. Schwab
Original Article Open access 06 May 2020 Pages: 1153 - 1159
Defining the Mechanism of Subarachnoid Hemorrhage–Induced Pyrexia
Ajith J. Thomas
Luis Ascanio-Cortez
Khalid A. Hanafy
Original Article 05 May 2020 Pages: 1160 - 1169
CCR1 Activation Promotes Neuroinflammation Through CCR1/TPR1/ERK1/2 Signaling Pathway After Intracerebral Hemorrhage in Mice
Jun Yan
Gang Zuo
Jiping Tang
Original Article 02 January 2020 Pages: 1170 - 1183
Development of a Neuroprotective Erythropoietin Modified with a Novel Carrier for the Blood–Brain Barrier
Po-Chuan Chiu
Houng-Chi Liou
Li-Jiuan Shen
Original Article 06 March 2020 Pages: 1184 - 1196
SIRT2 Inhibition Improves Functional Motor Recovery After Peripheral Nerve Injury
David Romeo-Guitart
Tatiana Leiva-Rodríguez
Caty Casas
Original Article 22 April 2020 Pages: 1197 - 1211
A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas
Kuo-Hao Ho
Peng-Hsu Chen
Ku-Chung Chen
Original Article 08 January 2020 Pages: 1212 - 1227
TSPO PET Identifies Different Anti-inflammatory Minocycline Treatment Response in Two Rodent Models of Epileptogenesis
Bettina J. Wolf
Mirjam Brackhan
Marion Bankstahl
Original Article Open access 22 January 2020 Pages: 1228 - 1238
Generalization of Conditioned Contextual Anxiety and the Modulatory Effects of Anxiety Sensitivity
Marta Andreatta
Dorothea Neueder
Paul Pauli
Original Article Open access 13 January 2020 Pages: 1239 - 1252
Activation of LXRβ Signaling in the Amygdala Confers Anxiolytic Effects Through Rebalancing Excitatory and Inhibitory Neurotransmission upon Acute Stress
Wen Yu
Lu Wang
Yu-Mei Wu
Original Article 15 April 2020 Pages: 1253 - 1270
ω-3PUFAs Improve Cognitive Impairments Through Ser133 Phosphorylation of CREB Upregulating BDNF/TrkB Signal in Schizophrenia
Cuiping Guo
Yi Liu
Xiaochuan Wang
Original Article 04 May 2020 Pages: 1271 - 1286
Anterior Cingulate Cortex Implants for Alcohol Addiction: A Feasibility Study
Sook Ling Leong
Paul Glue
Dirk De Ridder
Original Article 22 April 2020 Pages: 1287 - 1299
Finding Suitable Clinical Endpoints for a Potential Treatment of a Rare Genetic Disease: the Case of ARID1B
Matthijs D. Kruizinga
Rob G.J.A. Zuiker
Adam F. Cohen
Original Article Open access 22 May 2020 Pages: 1300 - 1310
ASENT2020 Annual Meeting Abstracts

Abstracts 04 August 2020 Pages: 1311 - 1323

Volume 17, Issue 3

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