Volume 16, issue 1, December 2015
294 articles in this issue
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KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome
Authors (first, second and last of 32)
- Anna A. W. M. Sanders
- Erik de Vrieze
- Oliver E. Blacque
- Content type: Research
- Open Access
- Published: 29 December 2015
- Article: 293
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Genome editing: the end of the beginning
Authors
- Jennifer A. Doudna
- Charles A. Gersbach
- Content type: Editorial
- Open Access
- Published: 23 December 2015
- Article: 292
This is part of 1 collection: -
High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
Authors (first, second and last of 14)
- Joseph L. McClay
- Andrey A. Shabalin
- Edwin J. C. G. van den Oord
- Content type: Research
- Open Access
- Published: 23 December 2015
- Article: 291
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Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation
Authors (first, second and last of 20)
- Stephan Busche
- Xiaojian Shao
- Elin Grundberg
- Content type: Research
- Open Access
- Published: 23 December 2015
- Article: 290
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Local compartment changes and regulatory landscape alterations in histone H1-depleted cells
Authors (first, second and last of 16)
- Geert Geeven
- Yun Zhu
- Wouter de Laat
- Content type: Research
- Open Access
- Published: 23 December 2015
- Article: 289
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3CPET: finding co-factor complexes from ChIA-PET data using a hierarchical Dirichlet process
Authors (first, second and last of 7)
- Mohamed Nadhir Djekidel
- Zhengyu Liang
- Michael Q. Zhang
- Content type: Method
- Open Access
- Published: 22 December 2015
- Article: 288
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Meta-analysis of RNA-seq expression data across species, tissues and studies
Authors
- Peter H. Sudmant
- Maria S. Alexis
- Christopher B. Burge
- Content type: Research
- Open Access
- Published: 22 December 2015
- Article: 287
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Towards a new era in medicine: therapeutic genome editing
Authors
- Matthew H. Porteus
- Content type: Review
- Open Access
- Published: 22 December 2015
- Article: 286
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Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging
Authors (first, second and last of 7)
- Shona H. Wood
- Sipko van Dam
- João Pedro de Magalhães
- Content type: Research
- Open Access
- Published: 22 December 2015
- Article: 285
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A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63
Authors (first, second and last of 7)
- Xiaomin Bao
- Adam J. Rubin
- Paul A. Khavari
- Content type: Research
- Open Access
- Published: 18 December 2015
- Article: 284
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Mineotaur: a tool for high-content microscopy screen sharing and visual analytics
Authors
- Bálint Antal
- Anatole Chessel
- Rafael E. Carazo Salas
- Content type: Open Letter
- Open Access
- Published: 17 December 2015
- Article: 283
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Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling
Authors (first, second and last of 7)
- J. David Barrass
- Jane E. A. Reid
- Sander Granneman
- Content type: Research
- Open Access
- Published: 17 December 2015
- Article: 282
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Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
Authors (first, second and last of 8)
- Wei Li
- Johannes Köster
- X. Shirley Liu
- Content type: Method
- Open Access
- Published: 16 December 2015
- Article: 281
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Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency
Authors (first, second and last of 8)
- Ying Dang
- Gengxiang Jia
- Haoquan Wu
- Content type: Research
- Open Access
- Published: 15 December 2015
- Article: 280
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Metagenome-assembled genomes uncover a global brackish microbiome
Authors (first, second and last of 7)
- Luisa W. Hugerth
- John Larsson
- Anders F. Andersson
- Content type: Research
- Open Access
- Published: 14 December 2015
- Article: 279
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MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
Authors (first, second and last of 12)
- Greg Finak
- Andrew McDavid
- Raphael Gottardo
- Content type: Method
- Open Access
- Published: 10 December 2015
- Article: 278
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Genomic legacy of the African cheetah, Acinonyx jubatus
Authors (first, second and last of 35)
- Pavel Dobrynin
- Shiping Liu
- Stephen J. O’Brien
- Content type: Research
- Open Access
- Published: 10 December 2015
- Article: 277
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The microbiome quality control project: baseline study design and future directions
Authors (first, second and last of 5)
- Rashmi Sinha
- Christian C. Abnet
- Curtis Huttenhower
- Content type: Open Letter
- Open Access
- Published: 09 December 2015
- Article: 276
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Erratum to: Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis
Authors (first, second and last of 13)
- Jiayan Fan
- Yue Xing
- Xianqun Fan
- Content type: Erratum
- Open Access
- Published: 09 December 2015
- Article: 275
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Five selfish reasons to work reproducibly
Authors
- Florian Markowetz
- Content type: Comment
- Open Access
- Published: 08 December 2015
- Article: 274
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A genome-wide survey of DNA methylation in hexaploid wheat
Authors (first, second and last of 6)
- Laura-Jayne Gardiner
- Mark Quinton-Tulloch
- Anthony Hall
- Content type: Research
- Open Access
- Published: 10 December 2015
- Article: 273
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Transcriptome-wide high-throughput deep m6A-seq reveals unique differential m6A methylation patterns between three organs in Arabidopsis thaliana
Authors (first, second and last of 7)
- Yizhen Wan
- Kai Tang
- Zhaobo Lang
- Content type: Research
- Open Access
- Published: 14 December 2015
- Article: 272
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Erratum to: Deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the DNA methylation landscape
Authors (first, second and last of 10)
- Lena Veselovska
- Sebastien A. Smallwood
- Gavin Kelsey
- Content type: Erratum
- Open Access
- Published: 03 December 2015
- Article: 271
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Erratum to: Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo
Authors (first, second and last of 7)
- Masahiko Imashimizu
- Hiroki Takahashi
- Mikhail Kashlev
- Content type: Erratum
- Open Access
- Published: 02 December 2015
- Article: 270
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Genetic determination of height-mediated mate choice
Authors (first, second and last of 4)
- Albert Tenesa
- Konrad Rawlik
- Oriol Canela-Xandri
- Content type: Research
- Open Access
- Published: 19 January 2016
- Article: 269
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Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2
Authors (first, second and last of 7)
- Young-Chae Kim
- Sangwon Byun
- Jongsook Kim Kemper
- Content type: Research
- Open Access
- Published: 04 December 2015
- Article: 268
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Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
Authors (first, second and last of 6)
- Christelle Etard
- Olivier Armant
- Uwe Strähle
- Content type: Research
- Open Access
- Published: 03 December 2015
- Article: 267
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Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
Authors (first, second and last of 18)
- Anthony S. Zannas
- Janine Arloth
- Divya Mehta
- Content type: Research
- Open Access
- Published: 17 December 2015
- Article: 266
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Identification of low abundance microbiome in clinical samples using whole genome sequencing
Authors (first, second and last of 9)
- Chao Zhang
- Kyle Cleveland
- Doron Betel
- Content type: Method
- Open Access
- Published: 27 November 2015
- Article: 265
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Glucocorticoid receptor and nuclear factor kappa-b affect three-dimensional chromatin organization
Authors (first, second and last of 13)
- Tatyana Kuznetsova
- Shuang-Yin Wang
- Hendrik G. Stunnenberg
- Content type: Research
- Open Access
- Published: 01 December 2015
- Article: 264
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Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Authors (first, second and last of 22)
- Maite Mendioroz
- Catherine Do
- Benjamin Tycko
- Content type: Research
- Open Access
- Published: 25 November 2015
- Article: 263
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Understanding Brassicaceae evolution through ancestral genome reconstruction
Authors (first, second and last of 8)
- Florent Murat
- Alexandra Louis
- Jerome Salse
- Content type: Research
- Open Access
- Published: 10 December 2015
- Article: 262
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Erratum to: Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data
Authors (first, second and last of 9)
- Franck Rapaport
- Raya Khanin
- Doron Betel
- Content type: Erratum
- Open Access
- Published: 23 November 2015
- Article: 261
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Resources for the design of CRISPR gene editing experiments
Authors
- Daniel B. Graham
- David E. Root
- Content type: Review
- Open Access
- Published: 27 November 2015
- Article: 260
This is part of 1 collection: -
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing
Authors (first, second and last of 9)
- Nicolas Servant
- Nelle Varoquaux
- Emmanuel Barillot
- Content type: Software
- Open Access
- Published: 01 December 2015
- Article: 259
This is part of 1 collection: -
Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease
Authors (first, second and last of 8)
- Tom Lawrenson
- Oluwaseyi Shorinola
- Wendy Harwood
- Content type: Research
- Open Access
- Published: 30 November 2015
- Article: 258
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Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications
Authors (first, second and last of 16)
- Ari E. Friedland
- Reshica Baral
- David Bumcrot
- Content type: Research
- Open Access
- Published: 24 November 2015
- Article: 257
This is part of 1 collection: -
The estrous cycle surpasses sex differences in regulating the transcriptome in the rat medial prefrontal cortex and reveals an underlying role of early growth response 1
Authors
- Florian Duclot
- Mohamed Kabbaj
- Content type: Research
- Open Access
- Published: 02 December 2015
- Article: 256
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Accelerating research through reagent repositories: the genome editing example
Authors
- J. Keith Joung
- Daniel F. Voytas
- Joanne Kamens
- Content type: Q&A
- Open Access
- Published: 20 November 2015
- Article: 255
This is part of 1 collection: -
Boosting plant immunity with CRISPR/Cas
Authors
- Angela Chaparro-Garcia
- Sophien Kamoun
- Vladimir Nekrasov
- Content type: Research Highlight
- Open Access
- Published: 19 November 2015
- Article: 254
This is part of 1 collection: -
Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
Authors (first, second and last of 7)
- Tautvydas Karvelis
- Giedrius Gasiunas
- Virginijus Siksnys
- Content type: Method
- Open Access
- Published: 19 November 2015
- Article: 253
This is part of 1 collection: -
P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis
Authors (first, second and last of 7)
- Chenghua Cui
- Ying Gan
- Dajun Deng
- Content type: Research
- Open Access
- Published: 23 November 2015
- Article: 252
This is part of 1 collection: -
The Cpf1 CRISPR-Cas protein expands genome-editing tools
Authors
- Robert D. Fagerlund
- Raymond H. J. Staals
- Peter C. Fineran
- Content type: Research Highlight
- Open Access
- Published: 17 November 2015
- Article: 251
This is part of 1 collection: -
Using genomics to combat infectious diseases on a global scale
Authors
- Amy K. Cain
- John A. Lees
- Content type: Meeting Report
- Open Access
- Published: 19 November 2015
- Article: 250
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Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining
Authors (first, second and last of 7)
- Mirko Singer
- Jennifer Marshall
- Friedrich Frischknecht
- Content type: Research
- Open Access
- Published: 17 November 2015
- Article: 249
This is part of 1 collection: -
CRISPR sabotage
Authors
- John van der Oost
- Stan J. J. Brouns
- Content type: Research Highlight
- Open Access
- Published: 09 November 2015
- Article: 248
This is part of 1 collection: -
Diversity of CRISPR-Cas immune systems and molecular machines
Authors
- Rodolphe Barrangou
- Content type: Review
- Open Access
- Published: 09 November 2015
- Article: 247
This is part of 1 collection: -
A transient ischemic environment induces reversible compaction of chromatin
Authors (first, second and last of 12)
- Ina Kirmes
- Aleksander Szczurek
- George Reid
- Content type: Research
- Open Access
- Published: 05 November 2015
- Article: 246
This is part of 1 collection: -
Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development
Authors (first, second and last of 8)
- Morten T. Venø
- Thomas B. Hansen
- Jørgen Kjems
- Content type: Research
- Open Access
- Published: 05 November 2015
- Article: 245