1. The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells

   • Nofar Yedid
   • Yael Kalma
   • Dalit Ben-Yosef

   Research article Open access 23 December 2016 Article: 952

   

2. Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

   • Susanne Schüler-Toprak
   • Julia Häring
   • Oliver Treeck

   Research article Open access 21 December 2016 Article: 951

   

3. Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009

   • Hala Ali
   • Sarah-Jo Sinnott
   • Zubair Kabir

   Research article Open access 20 December 2016 Article: 950

   

4. Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells

   • Xiaopeng Zhang
   • Chunchen Pan
   • Donghong Yu

   Research article Open access 16 December 2016 Article: 949

   

5. Is upfront stereotactic radiosurgery a rational treatment option for very elderly patients with brain metastases? A retrospective analysis of 106 consecutive patients age 80 years and older

   • Shoji Yomo
   • Motohiro Hayashi

   Research article Open access 15 December 2016 Article: 948

   

6. Transdifferentiation of pancreatic stromal tumor into leiomyosarcoma with metastases to liver and peritoneum: a case report

   • Chao Lin
   • Liping Wang
   • Xuewen Zhang

   Case report Open access 13 December 2016 Article: 947

   

7. A retrospective paired study: efficacy and toxicity of nimotuzumab versus cisplatin concurrent with radiotherapy in nasopharyngeal carcinoma

   • H. M. Li
   • P. Li
   • L. Liu

   Research article Open access 13 December 2016 Article: 946

   

8. Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

   • Mami Kaneko
   • Masanori Kotake
   • Toshinari Minamoto

   Research article Open access 12 December 2016 Article: 945

   

9. The impact of gender difference on operative time in laparoscopic partial nephrectomy for T1 renal tumor and the utility of retroperitoneal fat thickness as a predictor of operative time

   • Hiroki Ito
   • Kazuhide Makiyama
   • Masahiro Yao

   Research article Open access 12 December 2016 Article: 944

   

10. Prediction of cancer progression in a group of 73 gastric cancer patients by circulating cell-free DNA

    • Wang-Yang Pu
    • Rong Zhang
    • Chun-Gen Xing

    Research article Open access 09 December 2016 Article: 943

11. Oral perfluorooctane sulfonate (PFOS) lessens tumor development in the APC^min mouse model of spontaneous familial adenomatous polyposis

    • Jeffrey Wimsatt
    • Meghan Villers
    • Kim Innes

    Research article Open access 08 December 2016 Article: 942

    

12. Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells

    • Shirin R. Modarai
    • Lynn M. Opdenaker
    • Bruce M. Boman

    Research article Open access 07 December 2016 Article: 941

    

13. Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model

    • Veronika Caisová
    • Andra Vieru
    • Jan Ženka

    Research article Open access 07 December 2016 Article: 940

    

14. Erratum to: In vitro and in vivo activity of miR-92a–Locked Nucleic Acid (LNA)–Inhibitor against endometrial cancer

    • Anna Torres
    • Joanna Kozak
    • Kamil Torres

    Erratum Open access 07 December 2016 Article: 939

15. Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

    • Badar Mahmood
    • Morten Matthiesen Bach Damm
    • Mark Berner Hansen

    Research article Open access 07 December 2016 Article: 938

    

16. Patient preferences for palliative treatment of locally advanced or metastatic gastric cancer and adenocarcinoma of the gastroesophageal junction: a choice-based conjoint analysis study from Germany

    • R. Hofheinz
    • J. Clouth
    • P. Brück

    Research article Open access 06 December 2016 Article: 937

    

17. Tumour stage distribution and survival of malignant melanoma in Germany 2002–2011

    • Olaf Schoffer
    • Stefanie Schülein
    • Stefanie J. Klug

    Research article Open access 05 December 2016 Article: 936

    

18. Predicting general and cancer-related distress in women with newly diagnosed breast cancer

    • Andrea Gibbons
    • AnnMarie Groarke
    • Karl Sweeney

    Research article Open access 03 December 2016 Article: 935

    

19. Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

    • Simone Maistro
    • Natalia Teixeira
    • Maria Aparecida Azevedo Koike Folgueira

    Research article Open access 03 December 2016 Article: 934

20. Analysing population-based cancer survival – settling the controversies

    • Maja Pohar Perme
    • Jacques Estève
    • Bernard Rachet

    Research article Open access 03 December 2016 Article: 933

    

21. Role of geriatric intervention in the treatment of older patients with cancer: rationale and design of a phase III multicenter trial

    • Pierre Soubeyran
    • Catherine Terret
    • Muriel Rainfray

    Study protocol Open access 01 December 2016 Article: 932

    

22. The impact of medical tourism on colorectal screening among Korean Americans: A community-based cross-sectional study

    • Linda K. Ko
    • Victoria M. Taylor
    • John Inadomi

    Research article Open access 01 December 2016 Article: 931

23. A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

    • Zeb Saeed
    • Solaema Taleb
    • Carmella Evans-Molina

    Case report Open access 01 December 2016 Article: 930

    

24. Computational prediction of multidisciplinary team decision-making for adjuvant breast cancer drug therapies: a machine learning approach

    • Frank P. Y. Lin
    • Adrian Pokorny
    • Richard J. Epstein

    Research article Open access 01 December 2016 Article: 929

    

25. Erratum to: Insulin-like growth factor 1 receptor mediated tyrosine 845 phosphorylation of epidermal growth factor receptor in the presence of monoclonal antibody cetuximab

    • Gopal Iyer
    • James Price
    • Paul M. Harari

    Erratum Open access 01 December 2016 Article: 928

26. Preoperative conventional chemoradiotherapy versus short-course radiotherapy with delayed surgery for rectal cancer: results of a randomized controlled trial

    • Tadas Latkauskas
    • Henrikas Pauzas
    • Dainius Pavalkis

    Research article Open access 01 December 2016 Article: 927

    

27. Alternative splicing of estrogen receptor alpha in hepatocellular carcinoma

    • Jian Zhang
    • Jianwei Ren
    • Paul B. S. Lai

    Research article Open access 30 November 2016 Article: 926

    

28. Erratum to: 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells

    • Ruoxi Hong
    • Fei Ma
    • Wei Jiang

    Erratum Open access 30 November 2016 Article: 925

29. Tumor characteristics and prognosis in familial breast cancer

    • G. Arpino
    • M. Pensabene
    • S. De Placido

    Research article Open access 29 November 2016 Article: 924

    

30. Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study

    • Evangelia Pavlidou
    • Alexandros Daponte
    • Theodoros Agorastos

    Research article Open access 29 November 2016 Article: 923

31. HPV Prevalence in the Dutch cervical cancer screening population (DuSC study): HPV testing using automated HC2, cobas and Aptima workflows

    • Cornelis Johannes Jacobus Huijsmans
    • Willemina Rosalia Rita Geurts-Giele
    • Adrianus Johannes Christiaan van den Brule

    Research article Open access 28 November 2016 Article: 922

    

32. Erratum to: APC selectively mediates response to chemotherapeutic agents in breast cancer

    • Monica K. VanKlompenberg
    • Claire O. Bedalov
    • Jenifer R. Prosperi

    Erratum Open access 28 November 2016 Article: 921

    

33. Design of a randomized controlled trial of Internet-based cognitive behavioral therapy for treatment-induced menopausal symptoms in breast cancer survivors

    • Vera Atema
    • Marieke van Leeuwen
    • Neil K. Aaronson

    Study protocol Open access 25 November 2016 Article: 920

    

34. Cancer-related fatigue in post-treatment cancer survivors: application of the common sense model of illness representations

    • Teresa Corbett
    • AnnMarie Groarke
    • Brian E. McGuire

    Research article Open access 25 November 2016 Article: 919

    

35. Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial

    • Francesco Caponigro
    • Elena Di Gennaro
    • Alfredo Budillon

    Study protocol Open access 25 November 2016 Article: 918

    

36. Anti-LRP/LR-specific antibody IgG1-iS18 impedes adhesion and invasion of pancreatic cancer and neuroblastoma cells

    • Thalia M. Rebelo
    • Carryn J. Chetty
    • Stefan F. T. Weiss

    Research article Open access 24 November 2016 Article: 917

    

37. Erratum to: Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival

    • Sigurd M. Hald
    • Yury Kiselev
    • Tom Donnem

    Erratum Open access 24 November 2016 Article: 916

38. Increased Wnt5a in squamous cell lung carcinoma inhibits endothelial cell motility

    • J. Rapp
    • E. Kiss
    • J. E. Pongracz

    Research article Open access 23 November 2016 Article: 915

    

39. Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas

    • Eric T. Wong
    • Joshua Timmons
    • David C. Alsop

    Research article Open access 22 November 2016 Article: 914

    

40. A systematic comparison of copy number alterations in four types of female cancer

    • Fatemeh Kaveh
    • Lars O. Baumbusch
    • Hiroko K. Solvang

    Research article Open access 22 November 2016 Article: 913

    

41. Incidence and risk of hypertension in patients newly treated for multiple myeloma: a retrospective cohort study

    • Ajai Chari
    • Khalid Mezzi
    • Alexander R. Lyon

    Research article Open access 22 November 2016 Article: 912

    

42. Conservation of immune gene signatures in solid tumors and prognostic implications

    • Julia Chifman
    • Ashok Pullikuth
    • Lance D. Miller

    Research Article Open access 22 November 2016 Article: 911

    

43. The prognostic significance of human epidermal growth factor receptor family protein expression in operable pancreatic cancer

    • Qin Li
    • Lei Zhang
    • Bangwei Cao

    Research article Open access 21 November 2016 Article: 910

    

44. Comparing conVEntional RadioTherapy with stereotactIC body radiotherapy in patients with spinAL metastases: study protocol for an randomized controlled trial following the cohort multiple randomized controlled trial design

    • Joanne M. van der Velden
    • Helena M. Verkooijen
    • Marco van Vulpen

    Study protocol Open access 21 November 2016 Article: 909

    

45. Might radiation therapy in addition to chemotherapy improve overall survival of patients with non-oligometastatic Stage IV non-small cell lung cancer?: Secondary analysis of two prospective studies

    • ShengFa Su
    • YinXiang Hu
    • Bing Lu

    Research article Open access 21 November 2016 Article: 908

    

46. A phase I dose-escalation study of PEP02 (irinotecan liposome injection) in combination with 5-fluorouracil and leucovorin in advanced solid tumors

    • Nai-Jung Chiang
    • Tsu-Yi Chao
    • Li-Tzong Chen

    Research article Open access 21 November 2016 Article: 907

    

47. Chemotherapy curable malignancies and cancer stem cells: a biological review and hypothesis

    • Philip Savage

    Debate Open access 21 November 2016 Article: 906

    

48. Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients?

    • Laura Schirosi
    • Sabino Strippoli
    • Anita Mangia

    Research article Open access 18 November 2016 Article: 905

    

49. ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

    • Kristina Magnusson
    • Gabriela Gremel
    • Fredrik Pontén

    Research article Open access 18 November 2016 Article: 904

    

50. Keratin 19 as a key molecule in progression of human hepatocellular carcinomas through invasion and angiogenesis

    • Masato Takano
    • Keiji Shimada
    • Chiho Obayashi

    Research article Open access 18 November 2016 Article: 903