1. Preclinical validation of a novel oral Edaravone formulation for treatment of frontotemporal dementia

   • Sally Kelliny
   • Jing Xiong
   • Xin-Fu Zhou

   Original Article 02 October 2021 Pages: 1689 - 1707

   

2. Protective Effect of Chitosan Oligosaccharide against Hydrogen Peroxide-Mediated Oxidative Damage and Cell Apoptosis via Activating Nrf2/ARE Signaling Pathway

   • Xiaoxia Zhang
   • Shuang Liang
   • Xueling Dai

   Original Article 08 October 2021 Pages: 1708 - 1720

   

3. Race-Dependent Association of Single-Nucleotide Polymorphisms in TrkB Receptor in People Living with HIV and Depression

   • Valeria Avdoshina
   • Futoshi Yumoto
   • Rochelle E. Tractenberg

   Original Article 06 October 2021 Pages: 1721 - 1731

   

4. Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis

   • Mahdad Abdi
   • Parichehr Pasbakhsh
   • Adib Zendedel

   Original Article 27 September 2021 Pages: 1732 - 1746

   

5. The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus

   • Agnieszka Wąsik
   • Magdalena Białoń
   • Marcelina Żarnowska

   Original Article Open access 19 October 2021 Pages: 1747 - 1761

   

6. Neonatal Reserpine Administration Produces Widespread Neuronal Losses and ⍺-Synuclein Inclusions in a Rat Model

   • Rianita van Onselen
   • Tim G. Downing

   Original Article 02 November 2021 Pages: 1762 - 1770

7. LncRNA JHDM1D-AS1 Suppresses MPP + -Induced Neuronal Injury in Parkinson’s Disease via miR-134-5p/PIK3R3 Axis

   • Cuihui Wang
   • Hongying Zhang
   • Ji Li

   Original Article 13 November 2021 Pages: 1771 - 1781

   

8. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors

   • Anamaria Falcão Pereira
   • Mario Roberto Pontes Lisboa
   • Mariana Lima Vale

   Original Article 18 November 2021 Pages: 1782 - 1799

   

9. Luteolin Suppresses Microglia Neuroinflammatory Responses and Relieves Inflammation-Induced Cognitive Impairments

   • Wei Zhou
   • Mengmeng Hu
   • Zhangmin Xiang

   Original Article 16 October 2021 Pages: 1800 - 1811

   

10. Resveratrol Inhibits NLRP3 Inflammasome-Induced Pyroptosis and miR-155 Expression in Microglia Through Sirt1/AMPK Pathway

    • Kemal Ugur Tufekci
    • Bedir Irem Eltutan
    • Sermin Genc

    Original Article 05 November 2021 Pages: 1812 - 1829

    

11. Evidence That Methylphenidate Treatment Evokes Anxiety-Like Behavior Through Glucose Hypometabolism and Disruption of the Orbitofrontal Cortex Metabolic Networks

    • Felipe Schmitz
    • Josiane S. Silveira
    • Angela T. S. Wyse

    Original Article 19 November 2021 Pages: 1830 - 1845

    

12. d-Ribose-l-Cysteine Improves Glutathione Levels, Neuronal and Mitochondrial Ultrastructural Damage, Caspase-3 and GFAP Expressions Following Manganese-Induced Neurotoxicity

    • Grace T. Akingbade
    • Omamuyovwi M. Ijomone
    • Moyosore S. Ajao

    Original Article 04 September 2021 Pages: 1846 - 1858

    

13. Quercetin Exhibits α7nAChR/Nrf2/HO-1-Mediated Neuroprotection Against STZ-Induced Mitochondrial Toxicity and Cognitive Impairments in Experimental Rodents

    • Niraj Kumar Singh
    • Debapriya Garabadu

    Original Article 23 September 2021 Pages: 1859 - 1879

    

14. Apamin as a BBB Shuttle and Its Effects on T Cell Population During the Experimental Autoimmune Encephalomyelitis-Induced Model of Multiple Sclerosis

    • Haniye Fattahi
    • Nafiseh Esmaeil
    • Mehdi Aliomrani

    Original Article 06 September 2021 Pages: 1880 - 1891

    

15. Differences in Neuronal Numbers, Morphology, and Developmental Apoptosis in Mice Nigra Provide Experimental Evidence of Ontogenic Origin of Vulnerability to Parkinson’s Disease

    • D. J. Vidyadhara
    • Haorei Yarreiphang
    • Phalguni Anand Alladi

    Original Article 11 November 2021 Pages: 1892 - 1907

    

16. Fucoidan Modulated Oxidative Stress and Caspase-3 mRNA Expression Induced by Sulfoxaflor in the Brain of Mice

    • Petek Piner Benli
    • Merve Kaya
    • Cagil Coskun

    Original Article 27 September 2021 Pages: 1908 - 1919

    

17. Lacidipine Attenuates Symptoms of Nicotine Withdrawal in Mice

    • Kunal Khurana
    • Manish Kumar
    • Nitin Bansal

    Original Article 06 October 2021 Pages: 1920 - 1936

    

18. Ramelteon Mitigates Free Fatty Acid (FFA)–Induced Attachment of Monocytes to Brain Vascular Endothelial Cells

    • Guijie Wang
    • Fang Tian
    • Chunfeng Liu

    Original Article 18 November 2021 Pages: 1937 - 1945

    

19. Caffeine Improves GABA Transport in the Striatum of Spontaneously Hypertensive Rats (SHR)

    • Regina Célia Cussa Kubrusly
    • Thais da Rosa Valli
    • Maurício dos Santos Pereira

    Original Article 12 October 2021 Pages: 1946 - 1958

    

20. Isoquercitrin Upregulates Aldolase C Through Nrf2 to Ameliorate OGD/R-Induced Damage in SH-SY5Y Cells

    • Shi-Chang Cai
    • Chuan-An Yi
    • Xiu-Ping Li

    Original Article 13 November 2021 Pages: 1959 - 1969

    

21. Cortical Synaptic Reorganization Under Chronic Arsenic Exposure

    • Sandra A. Niño
    • Nallely Vázquez-Hernández
    • María E. Jiménez-Capdeville

    Original Article 17 September 2021 Pages: 1970 - 1980

    

22. LCZ696 Possesses a Protective Effect Against Homocysteine (Hcy)-Induced Impairment of Blood–Brain Barrier (BBB) Integrity by Increasing Occludin, Mediated by the Inhibition of Egr-1

    • Wenfeng Li
    • Wenjin Yuan
    • Kanghua Zeng

    Original Article 20 September 2021 Pages: 1981 - 1990

    

23. The Protective Effects of AT2R Agonist, CGP42112A, Against Angiotensin II-Induced Oxidative Stress and Inflammatory Response in Astrocytes: Role of AT2R/PP2A/NFκB/ROS Signaling

    • Shahnawaz Ali Bhat
    • Zoya Fatima
    • Kashif Hanif

    Original Article 16 September 2021 Pages: 1991 - 2006

    

24. MiRNA-494-3p Regulates Bupivacaine-Induced Neurotoxicity by the CDK6-PI3K/AKT Signaling

    • Licheng Zhang
    • Lifeng Zhang
    • Fengying Guo

    Original Article 15 October 2021 Pages: 2007 - 2017

    

25. Opicapone Protects Against Hyperhomocysteinemia-Induced Increase in Blood–Brain Barrier Permeability

    • Jian Wang
    • Bo Zheng
    • Jianhong Wang

    Original Article 28 October 2021 Pages: 2018 - 2028

    

26. Posttreatment Strategy Against Hypoxia and Ischemia Based on Selective Targeting of Nonnuclear Estrogen Receptors with PaPE-1

    • A. Wnuk
    • K. Przepiórska
    • M. Kajta

    Original Article Open access 19 November 2021 Pages: 2029 - 2041

    

27. The Role of PKC in Regulating NMDARs in Aluminum-Induced Learning and Memory Impairment in Rats

    • Chanting He
    • Jingjing Ji
    • Qiao Niu

    Original Article 09 September 2021 Pages: 2042 - 2055

    

28. Effects of Local Administration of Iron Oxide Nanoparticles in the Prefrontal Cortex, Striatum, and Hippocampus of Rats

    • Ellen Irrsack
    • Julia Schuller
    • Michael Koch

    Original Article Open access 27 October 2021 Pages: 2056 - 2071

    

29. On the Biomedical Properties of Endocannabinoid Degradation and Reuptake Inhibitors: Pre-clinical and Clinical Evidence

    • Karen Jaqueline Paredes-Ruiz
    • Karla Chavira-Ramos
    • Ana Laura Colín-González

    Review Article 06 November 2021 Pages: 2072 - 2097

    

30. Extracellular Vesicles and HIV-Associated Neurocognitive Disorders: Implications in Neuropathogenesis and Disease Diagnosis

    • Lee A. Campbell
    • Italo Mocchetti

    Review Article 07 October 2021 Pages: 2098 - 2107

    

31. RETRACTED ARTICLE: Exploring the Role of CLU in the Pathogenesis of Alzheimer’s Disease

    • Md. Sahab Uddin
    • Md. Tanvir Kabir
    • Ghulam Md Ashraf

    Review Article 21 August 2020 Pages: 2108 - 2119

    

32. Hard Boiled: Alcohol Use as a Risk Factor for MDMA-Induced Hyperthermia: a Systematic Review

    • Jan van Amsterdam
    • Tibor M. Brunt
    • Wim van den Brink

    Review Article Open access 23 September 2021 Pages: 2120 - 2133

    

33. Histone Deacetylases and Immediate Early Genes: Key Players in Psychostimulant-Induced Neuronal Plasticity

    • Veronica Bisagno
    • Jean Lud Cadet

    Review Article 28 September 2021 Pages: 2134 - 2140

    

34. Exploring the Role of Orexinergic Neurons in Parkinson’s Disease

    • Sachin Kumar
    • Tapan Behl
    • Simona Bungau

    Review Article 08 September 2021 Pages: 2141 - 2153

    

35. The Blood–Brain Barrier: Much More Than a Selective Access to the Brain

    • Fredy Sanchez-Cano
    • Luisa C. Hernández-Kelly
    • Arturo Ortega

    Review Article 22 October 2021 Pages: 2154 - 2174

    

36. GPR40 Agonist Ameliorate Pathological Neuroinflammation of Alzheimer’s Disease via the Modulation of Gut Microbiota and Immune System, a Mini-Review

    • Jianheng Chen
    • Qian Li
    • Jie Song

    Review Article 10 September 2021 Pages: 2175 - 2185

    

37. Sodium Butyrate Protects Against Ethanol-Induced Toxicity in SH-SY5Y Cell Line

    • Bruk Getachew
    • Antonei B. Csoka
    • Yousef Tizabi

    Short Communication 23 September 2021 Pages: 2186 - 2193