Articles

1. Bumetanide Attenuates Cognitive Deficits and Brain Damage in Rats Subjected to Hypoxia–Ischemia at Two Time Points of the Early Postnatal Period

   • Diorlon Nunes Machado
   • Luz Elena Durán-Carabali
   • Carlos Alexandre Netto

   Research 28 June 2023 Pages: 526 - 545

   

2. A Review on the Neurotoxic Effects of Doxorubicin

   • Katarzyna Kamińska
   • Agnieszka Cudnoch-Jędrzejewska

   Review Open access 23 June 2023 Pages: 383 - 397

   

3. Exercise Improves Orofacial Pain and Modifies Neuropeptide Expression in a Rat Model of Parkinson’s Disease

   • Karina Henrique Binda
   • Marucia Chacur
   • Daniel Oliveira Martins

   Research 02 June 2023 Pages: 459 - 470

   

4. p-Nrf2/HO-1 Pathway Involved in Methamphetamine-induced Executive Dysfunction through Endoplasmic Reticulum Stress and Apoptosis in the Dorsal Striatum

   • Tao Wei
   • Jun-Da Li
   • Dong-Liang Jiao

   Research 18 May 2023 Pages: 446 - 458

   

5. Mitochondrial Dysfunction as a Signaling Target for Therapeutic Intervention in Major Neurodegenerative Disease

   • Shubhada V. Mangrulkar
   • Nitu L. Wankhede
   • Tapan Behl

   Review 10 May 2023 Pages: 708 - 729

   

6. Human Placental Mesenchymal Stem Cell-derived Exosomes in Combination with Hyperbaric Oxygen Synergistically Promote Recovery after Spinal Cord Injury in Rats

   • Hosna Cheshmi
   • Hossein Mohammadi
   • Amir Raoofi

   Research 08 May 2023 Pages: 431 - 445

   

7. Posttreatment with Ospemifene Attenuates Hypoxia- and Ischemia-Induced Apoptosis in Primary Neuronal Cells via Selective Modulation of Estrogen Receptors

   • Bernadeta A. Pietrzak
   • Agnieszka Wnuk
   • Małgorzata Kajta

   Research Open access 02 May 2023 Pages: 362 - 379

   

8. In Silico Interactions of Natural and Synthetic Compounds with Key Proteins Involved in Alzheimer’s Disease: Prospects for Designing New Therapeutics Compound

   • Mehran Ebrahimi Shah-abadi
   • Armin Ariaei
   • Vahid Tavakolian Ferdousie

   Research 22 April 2023 Pages: 408 - 430

   

9. Connexin 43 Promotes Neurogenesis via Regulating Aquaporin-4 after Cerebral Ischemia

   • Heling Chu
   • Jing Dong
   • Qihao Guo

   Research 19 April 2023 Pages: 349 - 361

   

10. NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11

    • Shucheng Lin
    • Hao Cheng
    • Xiaofeng Zeng

    Research 15 April 2023 Pages: 398 - 407

    

11. Microglial Priming in Bilirubin-Induced Neurotoxicity

    • Hongmei Huang
    • Siyu Li
    • Ziyu Hua

    Research 14 April 2023 Pages: 338 - 348

    

12. CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice

    • Linxuan Zhang
    • Zehao Zeng
    • Fang Li

    Research 04 April 2023 Pages: 324 - 337

    

13. Correction to: Baicalin Attenuates Ketamine-Induced Neurotoxicity in the Developing Rats: Involvement of PI3K/Akt and CREB/BDNF/Bcl-2 Pathways

    • Daiying Zuo
    • Li Lin
    • Yingliang Wu

    Correction 29 March 2023 Pages: 380 - 381

    

14. Correction to: Protective Role of Epigallocatechin Gallate in a Rat Model of Cisplatin-Induced Cerebral Inflammation and Oxidative Damage: Impact of Modulating NF-κB and Nrf2

    • Manar Hamed Arafa
    • Hebatallah Husseini Atteia

    Correction 28 March 2023 Pages: 382 - 382

15. Blood–Brain Barrier Rescue by Roflumilast After Transient Global Cerebral Ischemia in Rats

    • Jéssica Mendes Bonato
    • Bianca Andretto de Mattos
    • Rúbia Maria Weffort de Oliveira

    Research 16 March 2023 Pages: 311 - 323

    

16. Pharmacological Inhibition of p-21 Activated Kinase (PAK) Restores Impaired Neurite Outgrowth and Remodeling in a Cellular Model of Down Syndrome

    • Natalia Barraza-Núñez
    • Ramón Pérez-Núñez
    • Pablo Caviedes

    Research Article 03 March 2023 Pages: 256 - 269

    

17. Impact of Plant-Derived Compounds on Amyotrophic Lateral Sclerosis

    • Lucas Matheus Gonçalves de Oliveira
    • Rodrigo Barreto Carreira
    • Silvia Lima Costa

    Review Article 17 February 2023 Pages: 288 - 309

    

18. Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP⁺-Induced SH-SY5Y Cells

    • Xiaoyi Lai
    • Yongjiang Zhang
    • Junqiang Yan

    Research Article 04 February 2023 Pages: 242 - 255

    

19. Protective Effects of Flavonoid Rutin Against Aminochrome Neurotoxicity

    • Fillipe Mendes De Araújo
    • Annyta F. Frota
    • Victor Diogenes Amaral Silva

    Research Article 01 February 2023 Pages: 224 - 241

    

20. Challenges and Opportunities of Metal Chelation Therapy in Trace Metals Overload-Induced Alzheimer’s Disease

    • Vinay Chaudhari
    • Siddhi Bagwe-Parab
    • Ginpreet Kaur

    Review Article 27 January 2023 Pages: 270 - 287

    

21. Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice

    • Mariam D. Oduola-Akande
    • Ismail O. Ishola
    • Olufunmilayo O. Adeyemi

    Research Article 27 January 2023 Pages: 212 - 223

    

22. Modulatory Role of Curcumin on Cobalt-Induced Memory Deficit, Hippocampal Oxidative Damage, Astrocytosis, and Nrf2 Expression

    • Rademene S. Oria
    • Godson E. Anyanwu
    • Omamuyovwi M. Ijomone

    Research Article 24 January 2023 Pages: 201 - 211

    

23. Neuroprotective and Immunomodulatory Effects of Probiotics in a Rat Model of Parkinson’s Disease

    • Irving Parra
    • Isabel Martínez
    • Liliana Mendieta

    Research Article 20 January 2023 Pages: 187 - 200

    

24. α-Synuclein-Induced Destabilized BMAL1 mRNA Leads to Circadian Rhythm Disruption in Parkinson’s Disease

    • Jun-Yi Liu
    • Jian Xue
    • Wan-Li Dong

    Research Article 20 January 2023 Pages: 177 - 186

    

25. Restraint Stress Exacerbates Apoptosis in a 6-OHDA Animal Model of Parkinson Disease

    • Sara El Idrissi
    • Nada Fath
    • Oualid Abboussi

    Research Article 12 January 2023 Pages: 166 - 176

    

26. Aryl Hydrocarbon Receptor in Glia Cells: A Plausible Glutamatergic Neurotransmission Orchestrator

    • Janisse Silva-Parra
    • Cristina Sandu
    • Arturo Ortega

    Review Article 06 January 2023 Pages: 103 - 117

    

27. Sodium Para-Aminosalicylic Acid Modulates Autophagy to Lessen Lead-Induced Neurodegeneration in Rat Cortex

    • Lei-lei Wang
    • Xiao-juan Zhu
    • Yue-ming Jiang

    Research Article 04 January 2023 Pages: 1 - 15

    

28. Catalpol Mitigates Alzheimer's Disease Progression by Promoting the Expression of Neural Stem Cell Exosomes Released miR-138-5p

    • Shengxi Meng
    • Huize Chen
    • Zeyu Meng

    Research Article Open access 03 January 2023 Pages: 41 - 56

    

29. Sevoflurane Preconditioning Downregulates GRIA1 Expression to Attenuate Cerebral Ischemia–Reperfusion-Induced Neuronal Injury

    • Ye Li
    • Zhi Liang
    • Kui Chi

    Research Article 03 January 2023 Pages: 29 - 40

    

30. Ioversol Induced Microglia Proinflammatory Activation and Oxidative Stress in Rats

    • Tao Li
    • Lili Zhao
    • Fang Kuang

    Research Article 03 January 2023 Pages: 149 - 165

    

31. Dihydromyricetin Protects Against Salsolinol-Induced Toxicity in Dopaminergic Cell Line: Implication for Parkinson’s Disease

    • Bruk Getachew
    • Antonei B. Csoka
    • Yousef Tizabi

    Research Article 31 December 2022 Pages: 141 - 148

    

32. CircUBE3B High Expression Participates in Sevoflurane-Induced Human Hippocampal Neuron Injury via Targeting miR-326 and Regulating MYD88 Expression

    • Xinye Qian
    • Shanshan Zheng
    • Yingfang Yu

    Research Article 31 December 2022 Pages: 16 - 28

    

33. l-2-Hydroxyglutaric Acid Administration to Neonatal Rats Elicits Marked Neurochemical Alterations and Long-Term Neurobehavioral Disabilities Mediated by Oxidative Stress

    • Rafael Teixeira Ribeiro
    • Andrey Vinícios Soares Carvalho
    • Moacir Wajner

    Research Article 29 December 2022 Pages: 119 - 140

    

34. Protective Mechanisms of 3-Acetyl-11-keto-β-Boswellic Acid and Piperine in Fluid Percussion Rat Model of Traumatic Brain Injury Targeting Nrf2 and NFkB Signaling

    • Satyabrata Kundu
    • Shamsher Singh

    Research Article 28 December 2022 Pages: 57 - 84

    

35. Therapeutic Molecular Insights into the Active Engagement of Cannabinoids in the Therapy of Parkinson’s Disease: A Novel and Futuristic Approach

    • Vaibhav Jain
    • Tapan Behl
    • Asim Najmi

    Review Article 26 December 2022 Pages: 85 - 102

    

36. Understanding the Intricate Role of Exosomes in Pathogenesis of Alzheimer’s Disease

    • Simran Chauhan
    • Tapan Behl
    • Hassan A. Alhazmi

    Review Article 24 December 2022 Pages: 1758 - 1773

    

37. Involvement of LARP7 in Activation of SIRT1 to Inhibit NF-κB Signaling Protects Microglia from Acrylamide-Induced Neuroinflammation

    • Jinxiu Guo
    • Hongjia Xue
    • Pei Jiang

    Research Article 23 December 2022 Pages: 2016 - 2026

    

38. Valproic Acid Attenuated PTZ-induced Oxidative Stress, Inflammation, and Apoptosis in the SH-SY5Y Cells via Modulating the TRPM2 Channel

    • Adem Ahlatcı
    • Kenan Yıldızhan
    • Muhammet Bektaş

    Research Article 20 December 2022 Pages: 1979 - 1988

    

39. Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways

    • Farzaneh Motafeghi
    • Abouzar Bagheri
    • Mohammad Shokrzadeh

    Research Article 16 December 2022 Pages: 1838 - 1858

    

40. Modulatory Activity of the Endocannabinoid System in the Development and Proliferation of Cells in the CNS

    • Hipolito A. Ruiz-Contreras
    • Abel Santamaría
    • Edgar Rangel-López

    Review Article 16 December 2022 Pages: 1690 - 1706

    

41. Neurotoxicity of Bisphenol A and the Impact of Melatonin Administration on Oxidative Stress, ERK/NF-kB Signaling Pathway, and Behavior in Rats

    • Alexandra C. Sevastre-Berghian
    • Cristina Casandra
    • Ioana Bâldea

    Research Article 14 December 2022 Pages: 1882 - 1894

    

42. miR-200a-3p Regulates PRKACB and Participates in Aluminium-Induced Tau Phosphorylation in PC12 Cells

    • Huan Li
    • Qun Liu
    • Qiao Niu

    Research Article Open access 02 December 2022 Pages: 1963 - 1978

    

43. Salsolinol Induces Parkinson’s Disease Through Activating NLRP3-Dependent Pyroptosis and the Neuroprotective Effect of Acteoside

    • Yumin Wang
    • Shuang Wu
    • Hongquan Wang

    Research Article 01 December 2022 Pages: 1948 - 1962

    

44. Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines

    • Kevin Doello
    • Cristina Mesas
    • Raúl Ortiz

    Brief Report Open access 30 November 2022 Pages: 1645 - 1652

    

45. Medicarpin Improves Depressive-Like Behaviors in a Chronic Unpredictable Mild Stress-Induced Mouse Model of Depression by Upregulating Liver X Receptor β Expression in the Amygdala

    • Yujiao Li
    • Xiaolu He
    • Guohua Zhou

    Research Article 29 November 2022 Pages: 1937 - 1947

    

46. Neonatal Isoflurane Exposure in Rats Impairs Short-Term Memory, Cell Viability, and Glutamate Uptake in Slices of the Frontal Cerebral Cortex, But Not the Hippocampus, in Adulthood

    • Laíse Figueiredo de Oliveira
    • Gabriela Godoy Poluceno
    • Carla Inês Tasca

    Research Article 28 November 2022 Pages: 1924 - 1936

    

47. COA-Cl Evokes Protective Responses Against H₂O₂-and 6-OHDA-Induced Toxic Injury in PC12 Cells

    • Mostofa Jamal
    • Ikuko Tsukamoto
    • Hiroshi Kinoshita

    Research Article 26 November 2022 Pages: 2061 - 2071

    

48. Biogenic Selenium Nanoparticles Attenuate Aβ_25–35-Induced Toxicity in PC12 Cells via Akt/CREB/BDNF Signaling Pathway

    • Lei Qiao
    • Yue Chen
    • Chunlan Xu

    Research Article 26 November 2022 Pages: 1869 - 1881

    

49. Combined Exposure to Chronic Sleep Deprivation and Caffeine Potentiates Behavioural Deficits by Altering Neurochemical Profile and Synaptophysin Expression in Long-Evans Rats

    • Edem Ekpenyong Edem
    • Uyi Emmanuel Okhonmina
    • Mujeeb Adekunle Adedokun

    Research Article 24 November 2022 Pages: 2001 - 2015

    

50. Epigallocatechin-3-gallate Enhances Cognitive and Memory Performance and Protects Against Brain Injury in Methionine-induced Hyperhomocysteinemia Through Interdependent Molecular Pathways

    • Mostafa D. Mostafa
    • Magda A ElKomy
    • Mohamed A. El-Missiry

    Research Open access 17 November 2022 Pages: 2103 - 2116