Sulphonylurea treatment of NIDDM patients with cardiovascular disease: a mixed blessing? G. LeibowitzE. Cerasi Review Pages: 503 - 514
Insulin-induced activation of phosphoinositide 3-kinase in Fao cells T. HayashiM. OkamotoK. Nakao Originals Pages: 515 - 522
Xenografts of porcine islets immunoprotected in hollow fibres reduce the incidence of diabetes in non-obese diabetic mice L. ChaillousS. DarquyP. Saï Originals Pages: 523 - 529
Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2 H. IwahashiT. HanafusaY. Matsuzawa Originals Pages: 530 - 536
Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: a comparative study with retinal capillary endothelial cells W. LiX. LiuX. Ye Originals Pages: 537 - 547
Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period R. N. WangL. BouwensG. Klöppel Originals Pages: 548 - 557
Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin J. DorrestijnD. M. OuwensJ. A. Maassen Originals Pages: 558 - 563
Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging A. J. ScheenJ. SturisE. Van Cauter Originals Pages: 564 - 572
Poor physical fitness, and impaired early insulin response but late hyperinsulinaemia, as predictors of NIDDM in middle-aged Swedish men K. -F. ErikssonF. Liridgärde Originals Pages: 573 - 579
Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects N. PaquotPh. SchneiterL. Tappy Originals Pages: 580 - 586
Captopril reduces the risk of nephropathy in IDDM patients with microalbuminuria The Microalbuminuria Captopril Study Group Originals Pages: 587 - 593
Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene A. DoriaJ. LeeA. S. Krolewski Originals Pages: 594 - 599
Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms S. UraE. ArakiM. Shichiri Originals Pages: 600 - 608
Does fall in tissue glucose precede fall in blood glucose? F. SternbergC. MeyerhoffE. F. Pfeiffer For Debate Pages: 609 - 612
Laboratory chow-induced insulin resistance: a possible contributor to autoimmune type 1 diabetes in rodents L. H. StorlienF. W. Scott Letter to the Editor Pages: 618 - 620