1. Quality Issues Identified During the Evaluation of Biosimilars by the European Medicines Agency’s Committee for Medicinal Products for Human Use

   • Mark Cilia
   • Sol Ruiz
   • John Joseph Borg

   Review Article 12 October 2017 Pages: 489 - 511

   

2. Preparation and Evaluation of Artemether Liposomes for Enhanced Anti-Tumor Therapy

   • Liu Tian
   • Jingjing Liu
   • Guihua Huang

   Review Article 16 October 2017 Pages: 512 - 521

   

3. Anti-inflammatory Effect from a Hydrogel Containing Nanoemulsified Copaiba oil (Copaifera multijuga Hayne)

   • Letícia G. Lucca
   • Sheila P. de Matos
   • Letícia S. Koester

   Research Article 21 August 2017 Pages: 522 - 530

   

4. Co-Spray Dried Mannitol/Poly(amidoamine)-Doxorubicin Dry-Powder Inhaler Formulations for Lung Adenocarcinoma: Morphology, In Vitro Evaluation, and Aerodynamic Performance

   • Qian Zhong

   Research Article 23 August 2017 Pages: 531 - 540

   

5. Formulation Screening and Freeze-Drying Process Optimization of Ginkgolide B Lyophilized Powder for Injection

   • Daichun Liu
   • Federico Galvanin
   • Ying Yu

   Research Article 28 August 2017 Pages: 541 - 550

   

6. Optimization of Curcuma Oil/Quinine-Loaded Nanocapsules for Malaria Treatment

   • Graziela Scheuer Gomes
   • Tamara Ramos Maciel
   • Sandra Elisa Haas

   Research Article 05 September 2017 Pages: 551 - 564

   

7. Laboratory Study Comparing Pharmacopeial Testing of Nebulizers with Evaluation Based on Nephele Mixing Inlet Methodology

   • Mårten Svensson
   • Elna Berg
   • Dennis Sandell

   Research Article 05 September 2017 Pages: 565 - 572

   

8. Appraisal of Transdermal Water-in-Oil Nanoemulgel of Selegiline HCl for the Effective Management of Parkinson’s Disease: Pharmacodynamic, Pharmacokinetic, and Biochemical Investigations

   • Sonal Setya
   • Tushar Madaan
   • Sushama Talegaonkar

   Research Article 05 September 2017 Pages: 573 - 589

   

9. Albumin-Conjugated Lipid-Based Multilayered Nanoemulsion Improves Drug Specificity and Anti-Inflammatory Potential at the Spinal Cord Injury gSite after Intravenous Administration

   • Xiao-Gang Chen
   • Fu Hua
   • Hong-Hui Tang

   Research Article 05 September 2017 Pages: 590 - 598

   

10. Development of a Mini-Freeze Dryer for Material-Sparing Laboratory Processing with Representative Product Temperature History

    • Wasfy M. Obeidat
    • Ekneet Sahni
    • Michael Pikal

    Research Article 13 September 2017 Pages: 599 - 609

    

11. Preparation, Characterization and In Vitro / In Vivo Evaluation of Oral Time-Controlled Release Etodolac Pellets

    • Xiaoyu Zhang
    • Qi Li
    • Weisan Pan

    Research Article 15 September 2017 Pages: 610 - 620

    

12. Magnetic Nanoparticles for the Delivery of Dapagliflozin to Hypoxic Tumors: Physicochemical Characterization and Cell Studies

    • Athina Angelopoulou
    • Efstathia Voulgari
    • Konstantinos Avgoustakis

    Research Article 18 September 2017 Pages: 621 - 633

    

13. Co-delivery of Vorinostat and Etoposide Via Disulfide Cross-Linked Biodegradable Polymeric Nanogels: Synthesis, Characterization, Biodegradation, and Anticancer Activity

    • Parveen Kumar
    • Lubna Wasim
    • Aruna Chhikara

    Research Article 25 September 2017 Pages: 634 - 647

    

14. Darunavir-Loaded Lipid Nanoparticles for Targeting to HIV Reservoirs

    • Jagruti Desai
    • Hetal Thakkar

    Research Article 25 September 2017 Pages: 648 - 660

    

15. Comparative Pharmaceutical Evaluation of Candesartan and Candesartan Cilexetil: Physicochemical Properties, In Vitro Dissolution and Ex Vivo In Vivo Studies

    • Ahmed M. Amer
    • Ahmed N. Allam
    • Ossama Y. Abdallah

    Research Article 25 September 2017 Pages: 661 - 667

    

16. Evaluating Current Practices in Shelf Life Estimation

    • Robert Capen
    • David Christopher
    • Walter Stroup

    Research Article Open access 25 September 2017 Pages: 668 - 680

    

17. Investigation of Dissolution Behavior HPMC/Eudragit^®/Magnesium Aluminometasilicate Oral Matrices Based on NMR Solid-State Spectroscopy and Dynamic Characteristics of Gel Layer

    • M. Naiserová
    • K. Kubová
    • P. Kulich

    Research Article 02 October 2017 Pages: 681 - 692

    

18. Mixed Liposome Approach for Ratiometric and Sequential Delivery of Paclitaxel and Gemcitabine

    • Yuanfen Liu
    • Hassan Tamam
    • Yoon Yeo

    Research Article 02 October 2017 Pages: 693 - 699

    

19. In vitro and In vivo Studies on a Novel Bioadhesive Colloidal System: Cationic Liposomes of Ibuprofen

    • Xiumei Gai
    • Lizhen Cheng
    • Xinggang Yang

    Research Article 02 October 2017 Pages: 700 - 709

    

20. In-Line Monitoring of a High-Shear Granulation Process Using the Baseline Shift of Near Infrared Spectra

    • Atsushi Kuriyama
    • Jin Osuga
    • Makoto Otsuka

    Research Article 02 October 2017 Pages: 710 - 718

    

21. Preparation and Evaluation of Taste Masking Iron Suspension: Taking Advantage of Weak Cationic Exchange Resin

    • Maryam Kouchak
    • Zahra Ramezani
    • Farid Bagheri

    Research Article 02 October 2017 Pages: 719 - 729

    

22. Enhanced Oral Bioavailability of Curcumin Using a Supersaturatable Self-Microemulsifying System Incorporating a Hydrophilic Polymer; In Vitro and In Vivo Investigations

    • Patcharawalai Jaisamut
    • Kamonthip Wiwattanawongsa
    • Ruedeekorn Wiwattanapatapee

    Research Article 03 October 2017 Pages: 730 - 740

    

23. Development of a New Aprepitant Liquisolid Formulation with the Aid of Artificial Neural Networks and Genetic Programming

    • Panagiotis Barmpalexis
    • Agni Grypioti
    • Dimitris G. Fatouros

    Research Article 04 October 2017 Pages: 741 - 752

    

24. In Vivo Human Skin Penetration Study of Sunscreens by Confocal Raman Spectroscopy

    • Vamshi Krishna Tippavajhala
    • Thiago de Oliveira Mendes
    • Airton Abrahão Martin

    Research Article 05 October 2017 Pages: 753 - 760

    

25. Improved Oral Bioavailability and Liver Targeting of Sorafenib Solid Lipid Nanoparticles in Rats

    • Haipeng Wang
    • Huiyun Wang
    • Baogang Xie

    Research Article 05 October 2017 Pages: 761 - 768

    

26. Investigation on Secondary Structure Perturbations of Proteins Embedded in Solid Lipid Matrices as a Novel Indicator of their Biological Activity upon In Vitro Release

    • Farrukh Zeeshan
    • Misbah Tabbassum
    • Natalie J. Medlicott

    Research Article 06 October 2017 Pages: 769 - 782

    

27. Systematical Investigation of Different Drug Nanocrystal Technologies to Produce Fast Dissolving Meloxicam Tablets

    • Tao Liu
    • Guili Yao
    • Jan P. Möschwitzer

    Research Article 10 October 2017 Pages: 783 - 791

    

28. Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer

    • Shallu Kutlehria
    • Gautam Behl
    • Mandip Singh

    Research Article 10 October 2017 Pages: 792 - 802

    

29. Release Mechanism Between Ion Osmotic Pressure and Drug Release in Ionic-Driven Osmotic Pump Tablets (I)

    • Lizhen Cheng
    • Siqi Gao
    • Xinggang Yang

    Research Article 10 October 2017 Pages: 803 - 811

    

30. Formulation and Pharmacokinetics of HSA-core and PLGA-shell Nanoparticles for Delivering Gemcitabine

    • Xinlong Wang
    • Yuheng Liang
    • Xing Tang

    Research Article 10 October 2017 Pages: 812 - 819

    

31. Polyethyleneimine and Chitosan Polymer-Based Mucoadhesive Liquid Crystalline Systems Intended for Buccal Drug Delivery

    • Giovana Maria Fioramonti Calixto
    • Francesca Damiani Victorelli
    • Marlus Chorilli

    Research Article 10 October 2017 Pages: 820 - 836

    

32. Drug Delivery from an Innovative LAMA/LABA Co-suspension Delivery Technology Fixed-Dose Combination MDI: Evidence of Consistency, Robustness, and Reliability

    • Amber Doty
    • Jon Schroeder
    • Peter Mack

    Research Article Open access 10 October 2017 Pages: 837 - 844

    

33. Bulk Freeze-Drying Milling: a Versatile Method of Developing Highly Porous Cushioning Excipients for Compacted Multiple-Unit Pellet Systems (MUPS)

    • Carin Ru Shan Siow
    • Paul Wan Sia Heng
    • Lai Wah Chan

    Research Article 10 October 2017 Pages: 845 - 857

    

34. Cubic Liquid Crystalline Gels Based on Glycerol Monooleate for Intra-articular Injection

    • Qian Li
    • Jiaojiao Cao
    • Xiaoqin Chu

    Research Article 12 October 2017 Pages: 858 - 865

    

35. Development and Optimization of a Starch-Based Co-processed Excipient for Direct Compression Using Mixture Design

    • Yonni E. Apeji
    • Avosuahi R. Oyi
    • Arvind K. Bansal

    Research Article 16 October 2017 Pages: 866 - 880

    

36. Liquid Nanosize Emulsion-Filled Enteric-Coated Capsules for Colon Delivery of Immunosuppressant Peptide

    • Sumit Sharma
    • Vivek Ranjan Sinha

    Research Article 17 October 2017 Pages: 881 - 885

    

37. First Steps towards the Pharmaceutical Development of Ovules Containing Lactobacillus Strains: Viability and Antimicrobial Activity as Basic First Parameters in Vaginal Formulations

    • A. L. Camilletti
    • F. O. Ruíz
    • I. L. Barberis

    Research Article 17 October 2017 Pages: 886 - 895

    

38. Effect of Arginine on the Aggregation of Protein in Freeze-Dried Formulations Containing Sugars and Polyol: 1—Formulation Development

    • Ellen Hackl
    • Joseph Darkwah
    • Irina Ermolina

    Research Article 18 October 2017 Pages: 896 - 911

    

39. The Relationship Between the Permeability and the Performance of Carrier-Based Dry Powder Inhalation Mixtures: New Insights and Practical Guidance

    • Ahmed O. Shalash
    • Nawal M. Khalafallah
    • Mustafa M. A. Elsayed

    Research Article 23 October 2017 Pages: 912 - 922

    

40. Characterization of the Dissolution Behavior of Piperine/Cyclodextrins Inclusion Complexes

    • Toshinari Ezawa
    • Yutaka Inoue
    • Ikuo Kanamoto

    Research Article 25 October 2017 Pages: 923 - 933

    

41. Improving Solubility and Oral Bioavailability of Febuxostat by Polymer-Coated Nanomatrix

    • Yi-Fan Yin
    • Yang Guo
    • Xuan Zhang

    Research Article 27 October 2017 Pages: 934 - 940

    

42. Using 3D Printing for Rapid Prototyping of Characterization Tools for Investigating Powder Blend Behavior

    • Cosima Hirschberg
    • Johan P. Boetker
    • Miriam Pein-Hackelbusch

    Research Article 02 November 2017 Pages: 941 - 950

    

43. Melts of Octaacetyl Sucrose as Oral-Modified Release Dosage Forms for Delivery of Poorly Soluble Compound in Stable Amorphous Form

    • Dorota Haznar-Garbacz
    • Ewa Kaminska
    • Piotr Kulinowski

    Research Article Open access 02 November 2017 Pages: 951 - 960

    

44. Dissolution Test of Tacrolimus Capsule: Effects of Filtration and Glass Adsorption

    • Kui Zeng
    • Zongming Gao
    • Wenlei Jiang

    Brief/Technical Note 21 August 2017 Pages: 961 - 964

45. Regulatory Notes on Impact of Excipients on Drug Products and the Maillard Reaction

    • Dipak K. Chowdhury
    • Haripada Sarker
    • Paul Schwartz

    Regulatory Note 25 September 2017 Pages: 965 - 969