1. Covariates in Pharmacometric Repeated Time-to-Event Models: Old and New (Pre)Selection Tools

   • Sebastiaan C. Goulooze
   • Elke H. J. Krekels
   • Catherijne A. J. Knibbe

   Research Article Open access 18 December 2018 Article: 11

   

2. Golimumab Dried Blood Spot Analysis (GOUDA): a Prospective Trial Showing Excellent Correlation with Venepuncture Samples and More Detailed Pharmacokinetic Information

   • Iris Detrez
   • Ganel Schops
   • Ann Gils

   Research Article 18 December 2018 Article: 10

   

3. Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A

   • Kun Peng
   • Yehong Wang
   • Tracy L. Staton

   Research Article 13 December 2018 Article: 9

   

4. PBPK and its Virtual Populations: the Impact of Physiology on Pediatric Pharmacokinetic Predictions of Tramadol

   • Huybrecht T’jollyn
   • An Vermeulen
   • Jan Van Bocxlaer

   Research Article 29 November 2018 Article: 8

   

5. The Assessment of Quality Attributes for Biosimilars: a Statistical Perspective on Current Practice and a Proposal

   • Johanna Mielke
   • Franz Innerbichler
   • Byron Jones

   Research Article 27 November 2018 Article: 7

   

6. Overlooked Issues on Pharmacokinetics Data Interpretation of Protein Drugs—a Case Example of Erythropoietin

   • Guohua An
   • Robert L. Schmidt
   • John A. Widness

   Brief/Technical Note 26 November 2018 Article: 6

   

7. Effect of the Plasticizer DEHP in Blood Collection Bags on Human Plasma Fraction Unbound Determination for Alpha-1-Acid Glycoprotein (AAG) Binding Drugs

   • Nicholas Ingram
   • Christopher Dishinger
   • Michael Huskin

   Research Article 16 November 2018 Article: 5

   

8. Approaches to Resolve False Reporting in Neutralizing Antibody Assays Caused by Reagent Leaching from Affinity Capture Elution Solid Phase

   • Yuhong Xiang
   • John Kamerud
   • Boris Gorovits

   Research Article 06 November 2018 Article: 4

   

9. In Vitro and In Vivo Efficacy of the Monocarboxylate Transporter 1 Inhibitor AR-C155858 in the Murine 4T1 Breast Cancer Tumor Model

   • Xiaowen Guan
   • Mark A. Bryniarski
   • Marilyn E. Morris

   Research Article 05 November 2018 Article: 3

   

10. The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360

    • Joseph W. Polli
    • Christopher R. McCurdy
    • for the AAPS Leadership

    Editorial 03 November 2018 Article: 2

11. Population Pharmacokinetics of AL-335 and Its Two Main Metabolites (ALS-022399, ALS-022227) in Monotherapy and in Combination with Odalasvir and/or Simeprevir

    • Elodie Valade
    • Thomas N. Kakuda
    • Oliver Ackaert

    Research Article 24 October 2018 Article: 1