A Proposal to Redefine Clinical Immunogenicity Assessment Daniel T. MytychM. Benjamin HockYanchen Zhou Commentary 28 February 2017 Pages: 599 - 602
Global Harmonization of Comparator Products for Bioequivalence Studies Luther GwazaJohn GordonAlfredo García-Arieta Commentary 06 March 2017 Pages: 603 - 606
Application of Pharmacokinetics and Pharmacodynamics in Product Life Cycle Management. A Case Study with a Carbidopa-Levodopa Extended-Release Formulation Nishit B. Modi Review Article 24 January 2017 Pages: 607 - 618
Scientific and Regulatory Considerations for Generic Complex Drug Products Containing Nanomaterials Nan ZhengDajun D. SunWenlei Jiang Review Article 23 January 2017 Pages: 619 - 631
Liposomal Drug Product Development and Quality: Current US Experience and Perspective Mamta KapoorSau L. LeeKatherine M. Tyner Review Article 03 February 2017 Pages: 632 - 641
Development Considerations for Nanocrystal Drug Products Mei-Ling ChenMathew JohnKatherine M. Tyner Review Article 09 March 2017 Pages: 642 - 651
Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes Javier O. MoralesKristin R. FatheHugh D. C. Smyth Review Article 13 February 2017 Pages: 652 - 668
Assessment of Correlation Between Early and Late Efficacy Endpoints to Identify Potential Surrogacy Relationships in Non-Hodgkin Lymphoma: a Literature-Based Meta-analysis of 108 Phase II and Phase III Studies Rui ZhuDan LuJin Yan Jin Review Article 21 February 2017 Pages: 669 - 681
Current Trends in Ligand Binding Real-Time Measurement Technologies Stephanie FraserJudy Y. ShihKarin Regnstrom Review Article 20 March 2017 Pages: 682 - 691
Spray-Dried Thiolated Chitosan-Coated Sodium Alginate Multilayer Microparticles for Vaginal HIV Microbicide Delivery Jianing MengVivek AgrahariBi-Botti C. Youan Research Article 30 January 2017 Pages: 692 - 702
Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects Jakob M. TownsendS. Connor DennisCory J. Berkland Research Article 30 January 2017 Pages: 703 - 711
Exploring Canine-Human Differences in Product Performance. Part II: Use of Modeling and Simulation to Explore the Impact of Formulation on Ciprofloxacin In Vivo Absorption and Dissolution in Dogs M. N. MartinezB. MistryR. M. Fahmy Research Article 06 March 2017 Pages: 712 - 726
Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers Noureddine HamitoucheEmmanuelle CometsBruno Laviolle Research Article 12 January 2017 Pages: 727 - 735
Identifying Metabolites of Meclonazepam by High-Resolution Mass Spectrometry Using Human Liver Microsomes, Hepatocytes, a Mouse Model, and Authentic Urine Samples Svante VikingssonAriane WohlfarthRobert Kronstrand Research Article Open access 13 January 2017 Pages: 736 - 742
Radiomitigation and Tissue Repair Activity of Systemically Administered Therapeutic Peptide TP508 Is Enhanced by PEGylation Scott D. McVicarKempaiah RayavaraDarrell H. Carney Research Article 17 January 2017 Pages: 743 - 753
Inclusion of Digestible Surfactants in Solid SMEDDS Formulation Removes Lag Time and Influences the Formation of Structured Particles During Digestion Kapilkumar VithaniAdrian HawleyBen J. Boyd Research Article 23 January 2017 Pages: 754 - 764
A Heparin Purification Process Removes Spiked Transmissible Spongiform Encephalopathy Agent Cyrus BettKsenija GrgacLuisa Gregori Research Article 23 January 2017 Pages: 765 - 771
Pharmacokinetic Steady-States Highlight Interesting Target-Mediated Disposition Properties Johan GabrielssonLambertus A. Peletier Research Article Open access 31 January 2017 Pages: 772 - 786
Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes Yi-an BiRenato J. ScialisManthena V. S. Varma Research Article 10 February 2017 Pages: 787 - 796
Phloretin Prevents High-Fat Diet-Induced Obesity and Improves Metabolic Homeostasis Sary AlsaneaMingming GaoDexi Liu Research Article 14 February 2017 Pages: 797 - 805
Advantageous Solubility-Permeability Interplay When Using Amorphous Solid Dispersion (ASD) Formulation for the BCS Class IV P-gp Substrate Rifaximin: Simultaneous Increase of Both the Solubility and the Permeability Avital BeigNoa Fine-ShamirArik Dahan Research Article 15 February 2017 Pages: 806 - 813
Aptamer-Conjugated Chitosan-Anchored Liposomal Complexes for Targeted Delivery of Erlotinib to EGFR-Mutated Lung Cancer Cells Fengqiao LiHao MeiLee Jia Research Article 23 February 2017 Pages: 814 - 826
Characterising Drug Release from Immediate-Release Formulations of a Poorly Soluble Compound, Basmisanil, Through Absorption Modelling and Dissolution Testing Cordula StillhartNeil J. ParrottAnikó Szepes Research Article 24 February 2017 Pages: 827 - 836
Modeling a Composite Score in Parkinson’s Disease Using Item Response Theory Gopichand GottipatiMats O. KarlssonElodie L. Plan Research Article Open access 28 February 2017 Pages: 837 - 845
A LC-MS All-in-One Workflow for Site-Specific Location, Identification and Quantification of N-/O- Glycosylation in Human Chorionic Gonadotropin Drug Products Hongbin ZhuChen QiuHongping Ye Research Article 28 February 2017 Pages: 846 - 855
Structure-Promiscuity Relationship Puzzles—Extensively Assayed Analogs with Large Differences in Target Annotations Ye HuSwarit JasialJürgen Bajorath Research Article 06 March 2017 Pages: 856 - 864
Pharmacokinetics of the Inhaled Selective Glucocorticoid Receptor Modulator AZD5423 Following Inhalation Using Different Devices Johanna MelinSusanne ProthonUlrika Wählby Hamrén Research Article 09 March 2017 Pages: 865 - 874
Evaluation of the Potency, Neutralizing Antibody Response, and Stability of a Recombinant Fusion Protein Vaccine for Streptococcus pyogenes E. BurletH. HogenEschG. Morefield Research Article 10 March 2017 Pages: 875 - 881
Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes Yi-an BiRenato J. ScialisManthena V. S. Varma Erratum 23 February 2017 Pages: 882 - 882
Erratum to: Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments Joseph C. MariniMichael AndersonRonald R. Bowsher Erratum 03 April 2017 Pages: 883 - 883