Use of Spray-Dried Dispersions in Early Pharmaceutical Development: Theoretical and Practical Challenges Jinjiang LiDhaval PatelGeorge Wang Review Article 28 November 2016 Pages: 321 - 333
Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization Amelia N. DeitchmanM. Tobias HeinrichsHartmut Derendorf Review Article 09 December 2016 Pages: 334 - 342
Clinical Translation of the National Institutes of Health’s Investments in Nanodrug Products and Devices Lori A. HendersonLalitha K. Shankar Review Article 19 December 2016 Pages: 343 - 359
Bioavailability and Bioequivalence Aspects of Oral Modified-Release Drug Products Rong WangDale P. ConnerBing V. Li Review Article 21 December 2016 Pages: 360 - 366
Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development Eric Peter ThelinKeri L. H. CarpenterAdel Helmy Review Article Open access 09 January 2017 Pages: 367 - 376
Approaches to Mitigate the Unwanted Immunogenicity of Therapeutic Proteins during Drug Development Laura I. Salazar-FontanaDharmesh D. DesaiAlexandra Joseph Review Article 12 January 2017 Pages: 377 - 385
Current Update of a Carboxymethylcellulose-PEG Conjugate Platform for Delivery of Insoluble Cytotoxic Agents to Tumors Yang YangJoseph BteichShyh-Dar Li Review Article 21 November 2016 Pages: 386 - 396
Insulin Formulation Characterization—the Thioflavin T Assays Morten Schlein Review Article 20 December 2016 Pages: 397 - 408
Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein Kaitlyn V. LedwitchArthur G. Roberts Review Article 27 December 2016 Pages: 409 - 420
Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells Yuqing YangFrancisco FuentesAh-Ng Kong Research Article 02 December 2016 Pages: 421 - 430
GDF11 Treatment Attenuates the Recovery of Skeletal Muscle Function After Injury in Older Rats Yu ZhouNeel SharmaTracy Criswell Research Article 06 December 2016 Pages: 431 - 437
A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9 Behnoush KhorsandSatheesh ElangovanAliasger K. Salem Research Article 10 January 2017 Pages: 438 - 446
Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure Jonathan HerskovitzJosiah RymanVibha Jawa Research Article 09 January 2017 Pages: 447 - 455
Tumor Static Concentration Curves in Combination Therapy Tim CardilinJoachim AlmquistJohan Gabrielsson Research Article Open access 28 September 2016 Pages: 456 - 467
Validation of a Drug-Resistant Anti-Adalimumab Antibody Assay to Monitor Immunogenicity in the Presence of High Concentrations of Adalimumab Sumin BianMarc FerranteAnn Gils Research Article 21 November 2016 Pages: 468 - 474
Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-Secreted Exosome Nanovesicles for the Treatment of Brain Cancer Tianzhi YangBrittany FogartyShuhua Bai Research Article 23 November 2016 Pages: 475 - 486
Population Pharmacokinetics of an Extended-Release Formulation of Exenatide Following Single- and Multiple-Dose Administration Brenda CirincioneJeffrey EdwardsDonald E. Mager Research Article Open access 28 November 2016 Pages: 487 - 496
A Model for Predicting the Interindividual Variability of Drug-Drug Interactions M. TodL. BourguignonS. Goutelle Research Article 06 December 2016 Pages: 497 - 509
Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling Abhinav TiwariAnson K. AbrahamPratap Singh Research Article 21 December 2016 Pages: 510 - 519
Tissue Concentration of Dodecafluoropentane (DDFP) Following Repeated IV Administration in the New Zealand White Rabbit Christine ArthurLin SongHoward Hendrickson Research Article 27 December 2016 Pages: 520 - 526
Exposure–Response and Tumor Growth Inhibition Analyses of the Monovalent Anti-c-MET Antibody Onartuzumab (MetMAb) in the Second- and Third-Line Non-Small Cell Lung Cancer Kelong HanPascal ChanuMark Stroh Research Article Open access 27 December 2016 Pages: 527 - 533
Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling Nicole A. KratochwilChristophe MeilleNeil J. Parrott Research Article Open access 03 January 2017 Pages: 534 - 550
Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients Ghada F. AhmedSai Praneeth R. BathenaAngela K. Birnbaum Research Article 09 January 2017 Pages: 551 - 556
An Integrated Assessment of the Effects of Immunogenicity on the Pharmacokinetics, Safety, and Efficacy of Elotuzumab Chaitali PasseyJohanna MoraManish Gupta Research Article 09 January 2017 Pages: 557 - 567
Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes Jeremy CarlierXingxing DiaoMarilyn A. Huestis Research Article Open access 09 January 2017 Pages: 568 - 577
Porous mannitol carrier for pulmonary delivery of cyclosporine A nanoparticles Sharon Shui Yee LeungJennifer WongHak-Kim Chan Research Article 09 January 2017 Pages: 578 - 586
Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations Scheyla D.V.S. SiqueiraAnette MüllertzThomas Rades Research Article 09 January 2017 Pages: 587 - 594
Erratum to: Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development Heather N. JacobsSona RathodJennifer H. Elisseeff Erratum 14 November 2016 Pages: 595 - 595
Erratum to: Tumor Static Concentration Curves in Combination Therapy Tim CardilinJoachim AlmquistJohan Gabrielsson Erratum 05 January 2017 Pages: 596 - 596
Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling Abhinav TiwariAnson K. AbrahamPratap Singh Erratum 17 January 2017 Pages: 597 - 597