Novel Lansoprazole-Loaded Nanoparticles for the Treatment of Gastric Acid Secretion-Related Ulcers: In Vitro and In Vivo Pharmacokinetic Pharmacodynamic Evaluation Milind AlaiWen Jen Lin Research Article 12 February 2014 Pages: 361 - 372
Sequential Bioequivalence Approaches for Parallel Designs Anders Fuglsang Research Article 14 February 2014 Pages: 373 - 378
Determination of the Most Influential Sources of Variability in Tacrolimus Trough Blood Concentrations in Adult Liver Transplant Recipients: A Bottom-Up Approach Cécile GérardJeanick StoccoMichel Tod Research Article 14 February 2014 Pages: 379 - 391
Stability: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team Nico van de MerbelNatasha SavoieJulie Diancin Review Article 19 February 2014 Pages: 392 - 399
Screening of Bioactive Peptides Using an Embryonic Stem Cell-Based Neurodifferentiation Assay Ruodan XuMaxime FeyeuxKarl-Heinz Krause Research Article 21 February 2014 Pages: 400 - 412
Commentary: Current Perspectives on the Aggregation of Protein Drugs Elizabeth M. Topp Commentary 22 February 2014 Pages: 413 - 414
Evaluation of Estimation Methods and Power of Tests of Discrete Covariates in Repeated Time-to-Event Parametric Models: Application to Gaucher Patients Treated by Imiglucerase Marie ViganJérôme StirnemannFrance Mentré Research Article 26 February 2014 Pages: 415 - 423
Multiscale Tumor Spatiokinetic Model for Intraperitoneal Therapy Jessie L.-S. AuPeng GuoM. Guillaume Wientjes Research Article 26 February 2014 Pages: 424 - 439
Analyzing Subvisible Particles in Protein Drug Products: a Comparison of Dynamic Light Scattering (DLS) and Resonant Mass Measurement (RMM) Jainik PanchalJoseph KotarekElizabeth M. Topp Research Article 26 February 2014 Pages: 440 - 451
A Priori Prediction of Tumor Payload Concentrations: Preclinical Case Study with an Auristatin-Based Anti-5T4 Antibody-Drug Conjugate Dhaval K. ShahLindsay E. KingMauricio Leal Research Article 01 March 2014 Pages: 452 - 463
Development of a Method That Eliminates False-Positive Results due to Nerve Growth Factor Interference in the Assessment of Fulranumab Immunogenicity Sheng DaiAllen SchantzGopi Shankar Research Article 05 March 2014 Pages: 464 - 477
A Network Modeling Approach for the Spatial Distribution and Structure of Bone Mineral Content Hui LiAidong ZhangMurali Ramanathan Research Article 27 March 2014 Pages: 478 - 487
A White Paper—Consensus and Recommendations of a Global Harmonization Team on Assessing the Impact of Immunogenicity on Pharmacokinetic Measurements J. M. SailstadL. AmaravadiJ. T. Wustner White Paper 29 March 2014 Pages: 488 - 498
New FDA Draft Guidance on Immunogenicity Ashwin ParenkyHeather MylerValerie Quarmby Meeting Report 29 March 2014 Pages: 499 - 503
Ligand Binding Assay Critical Reagents and Their Stability: Recommendations and Best Practices from the Global Bioanalysis Consortium Harmonization Team Lindsay E. KingEsme FarleyPriya Sriraman White Paper 01 April 2014 Pages: 504 - 515
Role of Public Standards in the Safety and Efficacy of Biologic Medicines Roger L. WilliamsAdrian F. BristowKrishna Menon Commentary 02 April 2014 Pages: 516 - 521
Polymeric Nanocarriers for Transport Modulation across the Pulmonary Epithelium: Dendrimers, Polymeric Nanoparticles, and their Nanoblends Balaji BharatwajRadovan DimovskiSandro R. P. da Rocha Research Article 02 April 2014 Pages: 522 - 538
In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate Nicky ThomasKatharina RichterThomas Rades Research Article 02 April 2014 Pages: 539 - 549
Influence of Surface Chemistry on Cytotoxicity and Cellular Uptake of Nanocapsules in Breast Cancer and Phagocytic Cells Ibrahima YoumJoseph D. BazzilBi-Botti C. Youan Research Article 04 April 2014 Pages: 550 - 567
Changes in Individual Drug-Independent System Parameters during Virtual Paediatric Pharmacokinetic Trials: Introducing Time-Varying Physiology into a Paediatric PBPK Model Khaled AbduljalilMasoud JameiTrevor N. Johnson Research Article 04 April 2014 Pages: 568 - 576
Rapid Delivery of Diazepam from Supersaturated Solutions Prepared Using Prodrug/Enzyme Mixtures: Toward Intranasal Treatment of Seizure Emergencies Mamta KapoorTate WinterRonald A. Siegel Research Article 04 April 2014 Pages: 577 - 585
Bioanalytical Method Validation: Concepts, Expectations and Challenges in Small Molecule and Macromolecule—A Report of PITTCON 2013 Symposium Edward D. BashawBinodh DeSilvaChinmay Shukla Meeting Report 04 April 2014 Pages: 586 - 591
Mapping the Target Localization and Biodistribution of Non-Radiolabeled VMAT2 Ligands in rat Brain Aifang DengXianying WuLin Zhu Research Article 05 April 2014 Pages: 592 - 599
Targeted Delivery of Curcumin to Tumors via PEG-Derivatized FTS-Based Micellar System Yichao ChenXiaolan ZhangSong Li Research Article 05 April 2014 Pages: 600 - 608
A Population Pharmacodynamic Model for Lactate Dehydrogenase and Neuron Specific Enolase to Predict Tumor Progression in Small Cell Lung Cancer Patients Núria Buil-BrunaJosé-María López-PicazoIñaki F. Trocóniz Research Article 17 April 2014 Pages: 609 - 619