Immunogenicity of Subcutaneously Administered Therapeutic Proteins—a Mechanistic Perspective Anas M. FathallahRichard B. BankertSathy V. Balu-Iyer Commentary 16 July 2013 Pages: 897 - 900
Population Pharmacokinetics of Cyclosporine in Transplant Recipients Kelong HanVenkateswaran C. PillaiRaman Venkataramanan Review Article 18 June 2013 Pages: 901 - 912
Physiologically Based Pharmacokinetic Modelling of Drug Penetration Across the Blood–Brain Barrier—Towards a Mechanistic IVIVE-Based Approach Kathryn BallFrançois BouzomXavier Declèves Review Article 20 June 2013 Pages: 913 - 932
Therapeutic Protein Drug–Drug Interactions: Navigating the Knowledge Gaps–Highlights from the 2012 AAPS NBC Roundtable and IQ Consortium/FDA Workshop Jane R. KennyMaggie M. LiuHonghui Zhou Meeting Report 21 June 2013 Pages: 933 - 940
Emerging Applications of Metabolomics in Studying Chemopreventive Phytochemicals Lei WangChi Chen Review Article 22 June 2013 Pages: 941 - 950
Phytochemicals from Cruciferous Vegetables, Epigenetics, and Prostate Cancer Prevention Gregory W. WatsonLaura M. BeaverEmily Ho Review Article 26 June 2013 Pages: 951 - 961
Silica Colloidal Crystals as Emerging Materials for High-Throughput Protein Electrophoresis Nadine K. NjoyaRobert E. BirdsallMary J. Wirth Research Article 26 June 2013 Pages: 962 - 969
Meeting Report: Metabolites in Safety Testing (MIST) Symposium—Safety Assessment of Human Metabolites: What’s REALLY Necessary to Ascertain Exposure Coverage in Safety Tests? Hongying GaoAbigail JacobsR. Scott Obach Meeting Report 03 July 2013 Pages: 970 - 973
International Guidelines for Bioequivalence of Systemically Available Orally Administered Generic Drug Products: A Survey of Similarities and Differences Barbara DavitApril C. BraddyLawrence X. Yu Review Article 03 July 2013 Pages: 974 - 990
Perspectives on the Role of Isoflavones in Prostate Cancer Aamir AhmadBernhard BiersackFazlul H. Sarkar Review Article 04 July 2013 Pages: 991 - 1000
Intraperitoneal Injection of Clodronate Liposomes Eliminates Visceral Adipose Macrophages and Blocks High-fat Diet-induced Weight Gain and Development of Insulin Resistance Le BuMingming GaoDexi Liu Research Article 04 July 2013 Pages: 1001 - 1011
A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy Binfeng XiaTycho HeimbachHandan He Research Article 09 July 2013 Pages: 1012 - 1024
Quantification of Swelling and Erosion in the Controlled Release of a Poorly Water-Soluble Drug Using Synchrotron X-ray Computed Microtomography Xianzhen YinHaiyan LiJiwen Zhang Research Article 16 July 2013 Pages: 1025 - 1034
Multiple Imputation of Missing Covariates in NONMEM and Evaluation of the Method’s Sensitivity to η-Shrinkage Åsa M. JohanssonMats O. Karlsson Research Article Open access 19 July 2013 Pages: 1035 - 1042
Impact of Osmotically Active Excipients on Bioavailability and Bioequivalence of BCS Class III Drugs Mei-Ling ChenNakissa SadriehLawrence Yu Regulatory Note 19 July 2013 Pages: 1043 - 1050
Population Pharmacodynamic Modeling of Hyperglycemic Clamp and Meal Tolerance Tests in Patients with Type 2 Diabetes Mellitus Ying HongJasper DingemanseDonald E. Mager Research Article 01 August 2013 Pages: 1051 - 1063
Epigenetic Cancer Prevention Mechanisms in Skin Cancer Kamalika SahaThomas J. HornyakRichard L. Eckert Review Article 01 August 2013 Pages: 1064 - 1071
A Report from the Pediatric Formulations Task Force: Perspectives on the State of Child-Friendly Oral Dosage Forms Anne ZajicekMichael J. FosslerDavid Douglas MacLaren Commentary 02 August 2013 Pages: 1072 - 1081
Effects of Selected OATP and/or ABC Transporter Inhibitors on the Brain and Whole-Body Distribution of Glyburide Nicolas TournierWadad SabaMichel Bottlaender Research Article 02 August 2013 Pages: 1082 - 1090
First Characterization of AKB-48 Metabolism, a Novel Synthetic Cannabinoid, Using Human Hepatocytes and High-Resolution Mass Spectrometry Adarsh S. GandhiMingshe ZhuMarilyn A. Huestis Research Article 03 August 2013 Pages: 1091 - 1098
Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2 Fanfan ZhouJian ZhengMichael Murray Research Article 06 August 2013 Pages: 1099 - 1108
Incorporation of Physiologically Based Pharmacokinetic Modeling in the Evaluation of Solubility Requirements for the Salt Selection Process: A Case Study Using Phenytoin Po-Chang ChiangHarvey Wong Research Article 14 August 2013 Pages: 1109 - 1118
Structure Activity Relationships in Alkylammonium C12-Gemini Surfactants Used as Dermal Permeation Enhancers Sérgio M. C. SilvaJoão J. S. SousaBozena B. Michniak-Kohn Research Article Open access 20 August 2013 Pages: 1119 - 1127
Mass Spectrometry-Based Targeted Proteomics as a Tool to Elucidate the Expression and Function of Intestinal Drug Transporters Stefan OswaldChristian GröerWerner Siegmund Review Article 28 August 2013 Pages: 1128 - 1140
A Mathematical Model of the Effect of Immunogenicity on Therapeutic Protein Pharmacokinetics Xiaoying ChenTimothy HicklingPaolo Vicini Research Article 30 August 2013 Pages: 1141 - 1154
2012 AAPS National Biotech Conference Open Forum: A Perspective on the Current State of Immunogenicity Prediction and Risk Management Manoj RajadhyakshaMeena SubramanyamBonnie Rup Meeting Report 30 August 2013 Pages: 1155 - 1159
Statistical and Bioanalytical Considerations for Establishing a Depletion Criterion for Specificity Testing During Immunogenicity Assessment of a Biotherapeutic R. O. DriscollL. ZhouV. Jawa Research Article 30 August 2013 Pages: 1160 - 1167
Effect of PEG Surface Conformation on Anticancer Activity and Blood Circulation of Nanoemulsions Loaded with Tocotrienol-Rich Fraction of Palm Oil Alaadin AlayoubiSaeed AlqahtaniSami Nazzal Research Article 30 August 2013 Pages: 1168 - 1179
Radionuclide Decorporation: Matching the Biokinetics of Actinides by Transdermal Delivery of Pro-chelators Yong ZhangMatthew P. SadgroveMichael Jay Research Article 30 August 2013 Pages: 1180 - 1188
A Markov Chain Model to Evaluate the Effect of CYP3A5 and ABCB1 Polymorphisms on Adverse Events Associated with Tacrolimus in Pediatric Renal Transplantation Sherwin K. B. SyJules HeubergerHartmut Derendorf Research Article 30 August 2013 Pages: 1189 - 1199
Flow Imaging Microscopy for Protein Particle Analysis—A Comparative Evaluation of Four Different Analytical Instruments Sarah ZöllsDaniel WeinbuchAndrea Hawe Research Article 31 August 2013 Pages: 1200 - 1211
Novel Hybrid GPU–CPU Implementation of Parallelized Monte Carlo Parametric Expectation Maximization Estimation Method for Population Pharmacokinetic Data Analysis C. M. Ng Research Article 04 September 2013 Pages: 1212 - 1221
Stable Isotope Dilution Mass Spectrometry for Membrane Transporter Quantitation Vahid FarrokhiAdam J. McShaneXudong Yao Mini-Review 11 September 2013 Pages: 1222 - 1231
Comparison of Methods for Handling Missing Covariate Data Åsa M. JohanssonMats O. Karlsson Research Article Open access 11 September 2013 Pages: 1232 - 1241
Impact of Genetic Polymorphism on Drug-Drug Interactions Mediated by Cytochromes: A General Approach Michel TodChristina Nkoud-MongoFrançois Gueyffier Research Article 12 September 2013 Pages: 1242 - 1252