Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene Ken-ichi HosoyaKazuhiro TetsukaHitomi Takanaga OriginalPaper 01 September 2000 Article: 27
No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in rats Anders LindahlSofia FridHans Lennernäs OriginalPaper 01 September 2000 Article: 26
Aerosol delivery of muramyl dipeptide to rodent lungs Ronald J. PettisIris HallAnthony J. Hickey OriginalPaper 01 September 2000 Article: 25
Direct pelletization in a rotary processor controlled by torque measurements. II: Effects of changes in the content of microcrystalline cellulose Jakob KristensenTorben SchæferPeter Kleinebudde OriginalPaper 01 September 2000 Article: 24
Recovery of human skin impedance in vivo after lontophoresis: Effect of metal ions Catherine CurdyYogeshvar N. KaliaRichard H. Guy OriginalPaper 01 September 2000 Article: 23
An interactive algorithm for the assessment of cumulative cortisol suppression during inhaled corticosteroid therapy Sriram KrishnaswamiGuenther HochhausHartmut Derendorf OriginalPaper 01 September 2000 Article: 22
Influence of degree of polymerization on behavior of cellulose during homogenization and extrusion/spheronization Peter KleinebuddeMuhannad JumaaFiras El Saleh OriginalPaper 01 September 2000 Article: 23
Human membrane transporter database: A web-accessible relational database for drug transport studies and pharmacogenomics Qing YanWolfgang Sadée OriginalPaper 01 September 2000 Article: 20
Particle size analysis of concentrated phospholipid microemulsions: II. Photon correlation spectroscopy Reza AboofazeliDavid J. BarlowM. Jayne Lawrence OriginalPaper 01 September 2000 Article: 19
Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice Swarupa G. KulkarniAnita A. PegramPhilip C. Smith OriginalPaper 22 June 2000 Article: 18
Stereoselective pharmacokinetics of ifosfamide in male and female rats Jeff J. WangHong LuKenneth K. Chan OriginalPaper 01 June 2000 Article: 17
Human proton/oligopeptide transporter (POT) genes: Identification of putative human genes using bioinformatics Christopher W. BotkaThomas W. WittigGordon L. Amidon OriginalPaper 01 June 2000 Article: 16
An experimental approach for investigating consumers evaluation of pharmacist consultation services Jon C. Schommer OriginalPaper 01 June 2000 Article: 15
Independence of substituent contributions to the transport of small-molecule permeants in lipid bilayer Peter T. MayerTian-Xiang XiangBradley D. Anderson OriginalPaper 01 June 2000 Article: 14
Particle size analysis of concentrated phospholipid microemulsions: I. Total intensity light scattering Reza AboofazeliDavid J. BarlowM. Jayne Lawrence OriginalPaper 01 June 2000 Article: 13
Light-scattering investigations on dilute nonionic oil-in-water microemulsions Warangkana WarisnoicharoenAlison B. LansleyM. Jayne Lawrence OriginalPaper 01 June 2000 Article: 12
Relationship between steady-state pharmacokinetics and hemodynamic effects of inhaled isobutyl nitrite in conscious rats William KielbasaHo-Leung Fung OriginalPaper 01 June 2000 Article: 11
Effect of rise in simulated inspiratory flow rate and carrier particle size on powder emptying from dry powder inhalers Varsha ChavanRichard Dalby OriginalPaper 01 June 2000 Article: 10
Synthesis and characterization of positively charged tPA as a prodrug using a heparin/protamine-based drug-delivery system Jun F. LiangYong T. LiVictor C. Yang OriginalPaper 21 March 2000 Article: 7
Comparative evaluation of the degree of indomethacin crystallinity by chemoinfometrical fourie-transformed near-infrared spectroscopy and conventional powder X-ray diffractiometry Makoto OtsukaFumie KatoYoshihisa Matsuda OriginalPaper 01 March 2000 Article: 9
Comparison of methods for analyzing kinetic data from mechanism-based enzyme inactivation: Application to nitric oxide synthase Tristan S. MaurerHo-Leung Fung OriginalPaper 01 March 2000 Article: 8
Targeted prodrug design to optimize drug delivery Hyo-Kyung HanGordon L. Amidon OriginalPaper 01 March 2000 Article: 6
Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides Chimanlall GoolcharranAndrew J. S. JonesRonald T. Borchardt OriginalPaper 01 March 2000 Article: 5
Pharmacogenomics: The promise of personalized medicine Laviero MancinelliMaureen CroninWolfgang Sadée OriginalPaper 01 March 2000 Article: 4
Maturation and growth of renal function: Dosing renally cleared drugs in children William L. Hayton OriginalPaper 01 March 2000 Article: 3
Molecular modeling of G-protein coupled receptor kinase 2: Docking and biochemical evaluation of inhibitors Matthias U. KassackPetra HöggerWolfgang Sadée OriginalPaper 01 March 2000 Article: 2
Pharmacokinetics of nevirapine and lamivudine in patients with HIV-1 infection John P. SaboMichael J. LamsonThomas R. MacGregor OriginalPaper 01 March 2000 Article: 1
Determination of membrane protein glycation in diabetic tissue Eric Y. ZhangPeter W. Swaan OriginalPaper 30 December 1999 Article: 20
Empirical versus mechanistic modelling: Comparison of an artificial neural network to a mechanistically based model for quantitative structure pharmacokinetic relationships of a homologous series of barbiturates Ivan NestorovMalcolm RowlandI. Petrov OriginalPaper 17 December 1999 Article: 17
Receptor-targeted gene delivery viafolate-conjugated polyethylenimine Wenjin GuoRobert J. Lee OriginalPaper 01 December 1999 Article: 19
Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P 4503A4 Meguru AchiraKiyomi ItoYuichi Sugiyama OriginalPaper 01 December 1999 Article: 18
Monoamine oxidase inhibitory properties of some benzazoles: Structure-; Activity relationships Teresa GrandiFabio SparatoreBernard Testa OriginalPaper 01 December 1999 Article: 16
Activity and kinetics of dissociation and transfer of amphotericin B from a novel delivery form Bradley Baaskatie KindtScott C. Hartsel OriginalPaper 26 September 1999 Article: 10
Kinetic modeling of plasmid DNA degradation in rat plasma Brett E. HoukGunther HochhausJeffrey A. Hughes OriginalPaper 22 September 1999 Article: 9
Reversed phase-high performance liquid chromatographic method to measure migration of semivolatile compound, vanillin, in ipratropium bromide inhalation solution Dennis ConkinsJulia E EconomouGordon Hansen OriginalPaper 01 September 1999 Article: 15
Inhibition of carboxyethylphosphoramide mustard formation from 4-hydroxycyclophosphamide by carmustine Song RenJohn T. Slattery OriginalPaper 01 September 1999 Article: 14
Evaluation of polyoxyethylene homopolymers for buccal bioadhesive drug delivery device formulations Deepak TiwariRobert SauseDavid Goldman OriginalPaper 01 September 1999 Article: 13
Function and immunolocalization of overexpressed human intestinal H+/peptide cotransporter in adenovirus-transduced Caco-2 cells Cheng-Pang HsuElke WalterGordon L. Amidon OriginalPaper 06 October 1999 Article: 12
A novel in vitro release method for submicron-sized dispersed systems N. ChidambaramD. J. Burgess OriginalPaper 01 September 1999 Article: 11
Kinetics of hallmark biochemical changes in paclitaxel-induced apoptosis Jessie L. S. AuM. Guill WientjesDong Li OriginalPaper 01 September 1999 Article: 8
A short-term (accelerated release) approach to evaluate peptide release from PLGA depot formulations Mohammed ShameemHeeyong LeePatrick P. DeLuca OriginalPaper 01 September 1999 Article: 7
A method to monitor DNA transfer during transfection Andrew L. JohnsonJoseph A. JurcisekJessie L. -S. Au OriginalPaper 25 June 1999 Article: 6
Design and synthesis of the CB1 selective cannabinoid antagonist AM281: A potential human SPECT ligand Ruoxi LanQian LuAlexandros Makriyannis OriginalPaper 20 June 1999 Article: 4
Prediction of dissolution-absorption relationships from a continuous dissolution/Caco-2 system Mark J. GinskiRajneesh TanejaJames E. Polli OriginalPaper 01 June 1999 Article: 3
The venus flytrap of periplasmic binding proteins: An ancient protein module present in multiple drug receptors Christian B. FelderRichard C. GraulWolfgang Sadee OriginalPaper 01 June 1999 Article: 2
Glycylsarcosine uptake in rabbit renal brush border membrane vesicles isolated from outer cortex or outer medulla: Evidence for heterogeneous distribution of oligopeptide transporters Chun-Jung LinDavid E. Smith OriginalPaper 01 June 1999 Article: 1