Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development Darshana JaniJohn AllinsonLaurie Stephen White Paper 16 September 2015 Pages: 1 - 14
Dissolution Similarity Requirements: How Similar or Dissimilar Are the Global Regulatory Expectations? Dorys Argelia DiazStephen T. ColganLeslie Van Alstine Commentary 01 October 2015 Pages: 15 - 22
Novel Nanostructured Solid Materials for Modulating Oral Drug Delivery from Solid-State Lipid-Based Drug Delivery Systems Tahnee J. DeningShasha RaoClive A. Prestidge Review Article 09 September 2015 Pages: 23 - 40
Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands Camillo RosanoMarco PonassiRosamaria Lappano Mini-Review 16 November 2015 Pages: 41 - 46
Pattern Recognition in Pharmacokinetic Data Analysis Johan GabrielssonBernd MeibohmDaniel Weiner Tutorial 03 September 2015 Pages: 47 - 63
Pattern Recognition in Pharmacodynamic Data Analysis Johan GabrielssonStephan Hjorth Tutorial 05 November 2015 Pages: 64 - 91
Approaches to the Development of Human Health Toxicity Values for Active Pharmaceutical Ingredients in the Environment Tamara L. Sorell Research Article 03 September 2015 Pages: 92 - 101
Preparation and Evaluation of Phospholipid-Based Complex of Standardized Centella Extract (SCE) for the Enhanced Delivery of Phytoconstituents Suprit D. SaojiNishikant A. RautVivek S. Dave Research Article 12 November 2015 Pages: 102 - 114
Evaluation of IgE Antibodies to Omalizumab (Xolair®) and Their Potential Correlation to Anaphylaxis Dana L. BakerGerald R. NakamuraSaloumeh Kadkhodayan Fischer Research Article 04 September 2015 Pages: 115 - 123
Pharmacokinetics of Morphine and Its Metabolites in Infants and Young Children After Congenital Heart Surgery Mohammed H. ElkomyDavid R. DroverGregory B. Hammer Research Article 09 September 2015 Pages: 124 - 133
Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells Jing-Jing WuGuang-Bo GeLing Yang Research Article 11 September 2015 Pages: 134 - 145
Thermosensitive Hydrogel Co-loaded with Gold Nanoparticles and Doxorubicin for Effective Chemoradiotherapy Tingting LiMingfu ZhangNa Zhang Research Article 17 September 2015 Pages: 146 - 155
A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins Katherine L. GillIain GardnerMasoud Jamei Research Article Open access 25 September 2015 Pages: 156 - 170
Pharmacokinetic Interactions for Drugs with a Long Half-Life—Evidence for the Need of Model-Based Analysis Elin M. SvenssonChayan AcharyaMats O. Karlsson Research Article Open access 13 October 2015 Pages: 171 - 179
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS) Maria Høtoft MichaelsenKishor M. WasanThomas Rades Research Article 20 October 2015 Pages: 180 - 186
A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis Denison J. KuruvillaJohn A. WidnessPeter Veng-Pedersen Research Article 26 October 2015 Pages: 187 - 195
Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data Thierry WendlingNikolaos TsamandourasLeon Aarons Research Article 04 November 2015 Pages: 196 - 209
Chemical Potency and Degradation Products of Medications Stored Over 550 Earth Days at the International Space Station Virginia E. Wotring Research Article 06 November 2015 Pages: 210 - 216
Modeling Testosterone Circadian Rhythm in Hypogonadal Males: Effect of Age and Circannual Variations Mario González-SalesOlivier BarrièreMario Tanguay Research Article Open access 09 November 2015 Pages: 217 - 227
A Whole-Body Physiologically Based Pharmacokinetic Model of Gefitinib in Mice and Scale-Up to Humans Youwei BiJiexin DengGuohua An Research Article 11 November 2015 Pages: 228 - 238
Platelet Dynamics in Peritoneal Carcinomatosis Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Oxaliplatin Carlos Pérez-RuixoBelén ValenzuelaJuan José Pérez-Ruixo Research Article 17 November 2015 Pages: 239 - 250
BDDCS Predictions, Self-Correcting Aspects of BDDCS Assignments, BDDCS Assignment Corrections, and Classification for more than 175 Additional Drugs Chelsea M. HoseyRosa ChanLeslie Z. Benet Research Article 20 November 2015 Pages: 251 - 260
Novel Injectable Pentablock Copolymer Based Thermoresponsive Hydrogels for Sustained Release Vaccines Sharan BobbalaViral TamboliSarah Hook Research Article 20 November 2015 Pages: 261 - 269
Population Pharmacokinetics of Paritaprevir, Ombitasvir, Dasabuvir, Ritonavir, and Ribavirin in Patients with Hepatitis C Virus Genotype 1 Infection: Combined Analysis from 9 Phase 1b/2 Studies Sven MensingAkshanth R. PolepallySandeep Dutta Research Article 23 November 2015 Pages: 270 - 280
Pharma Success in Product Development—Does Biotechnology Change the Paradigm in Product Development and Attrition Ronald P. Evens Meeting Report 16 October 2015 Pages: 281 - 285