1. An Overview of Patent Law as Applied to the Field of Veterinary Medicine

   • James M. Gould

   Review Article Open access 05 February 2008 Pages: 1 - 8

2. The Role of Quantitative Pharmacology in an Academic Translational Research Environment

   • Jeffrey S. Barrett

   ReviewArticleThemedIssue:QuantitativePharmacolog,aRoadmapforRational,Model-BasedDrugDevelopmentGuestEditor:BerndMeibohm Open access 05 February 2008 Pages: 9 - 14

   

3. Cell Cycle Checkpoint Models for Cellular Pharmacology of Paclitaxel and Platinum Drugs

   • Ardith W. El-Kareh
   • Rachel E. Labes
   • Timothy W. Secomb

   Research Article 05 February 2008 Pages: 15 - 34

   

4. Informatic Tools and Approaches in Postmarketing Pharmacovigilance Used by FDA

   • Joyce Weaver
   • Mary Willy
   • Mark Avigan

   ReviewArticleThemedIssueBioinformaticsandComputationalAdvancesinthePharmaceuticalSciencesGuestEditor:MuraliRamanathan Open access 25 January 2008 Pages: 35 - 41

5. The Pharmacokinetics and Interactions of Ivermectin in Humans—A Mini-review

   • Aránzazu González Canga
   • Ana M. Sahagún Prieto
   • Juan J. García Vieitez

   Mini-Review Open access 25 January 2008 Pages: 42 - 46

6. Pharmacokinetic Interaction between the Flavonoid Luteolin and γ-Hydroxybutyrate in Rats: Potential Involvement of Monocarboxylate Transporters

   • Xiaodong Wang
   • Qi Wang
   • Marilyn E. Morris

   Research Article 30 January 2008 Pages: 47 - 55

   

7. Pharmacokinetics of 1,4-Butanediol in Rats: Bioactivation to γ-Hydroxybutyric Acid, Interaction with Ethanol, and Oral Bioavailability

   • Ho-Leung Fung
   • Pei-Suen Tsou
   • Sun Mi Fung

   Research Article 08 February 2008 Pages: 56 - 69

   

8. A Flexible Nonlinear Feedback System That Captures Diverse Patterns of Adaptation and Rebound

   • Johan Gabrielsson
   • Lambertus A. Peletier

   Review Article/Themed Issue: Bioinformatics and Computational Advances in the Pharmaceutical Sciences/Guest Editor: Murali Raman Open access 22 February 2008 Pages: 70 - 83

   

9. Rheological Evaluation of Silicon/Carbopol Hydrophilic Gel Systems as a Vehicle for Delivery of Water Insoluble Drugs

   • Giulia Bonacucina
   • Marco Cespi
   • Giovanni F. Palmieri

   Research Article 05 February 2008 Pages: 84 - 91

   

10. Prodrug Approaches for CNS Delivery

    • Jarkko Rautio
    • Krista Laine
    • Jouko Savolainen

    Research Article/Themed Issue: Current Advances in CNS Delivery of Therapeutic Molecules Guest Editors: Jean-Michel Scherrmann a 05 February 2008 Pages: 92 - 102

    

11. FDA Critical Path Initiatives: Opportunities for Generic Drug Development

    • Robert A. Lionberger

    Review Article;Themed Issue:Bioequivalence, Biopharmaceutics Classification System, and Beyond/Guest Editor:James E. Polli Open access 20 February 2008 Pages: 103 - 109

    

12. Pharmacogenetic and Metabolic Differences Between Dog Breeds: Their Impact on Canine Medicine and the Use of the Dog as a Preclinical Animal Model

    • Steven Fleischer
    • Michele Sharkey
    • Marilyn Martinez

    Review Article Open access 15 February 2008 Pages: 110 - 119

    

13. Percutaneous Permeation Enhancement by Terpenes: Mechanistic View

    • Bharti Sapra
    • Subheet Jain
    • A. K. Tiwary

    Review Article Open access 08 February 2008 Pages: 120 - 132

14. Nanoparticles Containing Anti-inflammatory Agents as Chemotherapy Adjuvants: Optimization and In Vitro Characterization

    • Xiuling Lu
    • Melissa D. Howard
    • Markos Leggas

    Research Article 04 March 2008 Pages: 133 - 140

    

15. Evaluation of Methods for Estimating Time to Steady State with Examples from Phase 1 Studies

    • Lata Maganti
    • Deborah L. Panebianco
    • Andrea L. Maes

    Review Article Open access 28 February 2008 Pages: 141 - 147

16. Highly Variable Drugs: Observations from Bioequivalence Data Submitted to the FDA for New Generic Drug Applications

    • Barbara M. Davit
    • Dale P. Conner
    • Lawrence X. Yu

    Research Article 05 March 2008 Pages: 148 - 156

    

17. Pharmacokinetically-Guided Lead Optimization of Nitrofuranylamide Anti-Tuberculosis Agents

    • Nageshwar R. Budha
    • Nitin Mehrotra
    • Bernd Meibohm

    Research Article 14 March 2008 Pages: 157 - 165

    

18. Recent Advances in Blood–Brain Barrier Disruption as a CNS Delivery Strategy

    • Marc-André Bellavance
    • Marie Blanchette
    • David Fortin

    Review Article/Themed Issue: Current Advances in CNS Delivery of Therapeutic Molecules Guest Editors: Jean-Michael Scherrman and Open access 18 March 2008 Pages: 166 - 177

    

19. Role of Biotransformation Studies in Minimizing Metabolism-Related Liabilities in Drug Discovery

    • Yue-Zhong Shu
    • Benjamin M. Johnson
    • Tian J. Yang

    Review Article Open access 13 March 2008 Pages: 178 - 192

    

20. Sodium-coupled Monocarboxylate Transporters in Normal Tissues and in Cancer

    • Vadivel Ganapathy
    • Muthusamy Thangaraju
    • Puttur D. Prasad

    Mini-Review/Themed Issue: Monocarboxylate Transporters in Drug Disposition/Guest Editor: Marilyn Morris Open access 02 April 2008 Pages: 193 - 199

    

21. Reaction Phenotyping: Current Industry Efforts to Identify Enzymes Responsible for Metabolizing Drug Candidates

    • Timothy W. Harper
    • Patrick J. Brassil

    Mini-Review/Themed Issue: Enabling Drug Developability: Defining Metabolism Properties of New Drug Candidates During Drug Discov 05 April 2008 Pages: 200 - 207

    

22. Use of the Biopharmaceutical Classification System in Early Drug Development

    • M. Sherry Ku

    Research Article 03 April 2008 Pages: 208 - 212

23. Application of Gastrointestinal Simulation for Extensions for Biowaivers of Highly Permeable Compounds

    • Marija Tubic-Grozdanis
    • Michael B. Bolger
    • Peter Langguth

    Research Article/Themed Issue: Bioequivalence, Biopharmaceutics Classification System, and Beyond Guest Editors: James E. Polli, 02 April 2008 Pages: 213 - 226

    

24. Announcing AAPS and FDA Agreement to Build Quantitative Alzheimer's Disease Model

    • Peter Inchauteguiz

    Announcement 01 April 2008 Pages: 227 - 227