1. Introduction

   • Hitoshi Kikutani

   OriginalPaper Pages: 175 - 176

2. IL-6

   • Tadamitsu Kishimoto

   OriginalPaper Pages: 177 - 185

3. Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer

   • Raja Atreya
   • Markus F. Neurath

   OriginalPaper Pages: 187 - 195

4. Role of IL-6 in spinal cord injury in a mouse model

   • Masaya Nakamura
   • Seiji Okada
   • Hideyuki Okano

   OriginalPaper Pages: 197 - 203

5. Negative regulation of cytokine signaling

   • Akihiko Yoshimura

   OriginalPaper Pages: 205 - 220

6. Clinical studies in patients with Castleman’s disease, Crohn’s disease, and rheumatoid arthritis in Japan

   • Norihiro Nishimoto

   OriginalPaper Pages: 221 - 229

7. Clinical study of tocilizumab in children with systemic-onset juvenile idiopathic arthritis

   • Shumpei Yokota
   • Takako Miyamae
   • Masaaki Mori

   OriginalPaper Pages: 231 - 237

8. Pro-inflammatory cytokines in rheumatoid arthritis

   • Josef S. Smolen
   • Kurt Redlich
   • Georg Schett

   OriginalPaper Pages: 239 - 248

9. Role of IL-6 in the neural stem cell differentiation

   • Tetsuya Taga
   • Shinji Fukuda

   OriginalPaper Pages: 249 - 256

10. Pathological role of IL-6 in the experimental allergic bronchial asthma in mice

    • Aysefa Doganci
    • Kerstin Sauer
    • Susetta Finotto

    OriginalPaper Pages: 257 - 269