1. Letter from the Editor-in-Chief, 2017

   • Lawrence J. Berliner

   Introduction 15 February 2017 Pages: 1 - 1

2. Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration

   • Steven J. Collins
   • Cathryn L. Haigh

   Methods Paper 28 October 2016 Pages: 3 - 13

   

3. Can We Rely on Computational Predictions To Correctly Identify Ligand Binding Sites on Novel Protein Drug Targets? Assessment of Binding Site Prediction Methods and a Protocol for Validation of Predicted Binding Sites

   • Neal K. Broomhead
   • Mahmoud E. Soliman

   Review Paper 31 October 2016 Pages: 15 - 23

   

4. Amino Acid Properties of Trafficking Determinants in the Outer Pore-Forming Region of Kv1 Potassium Channels in Cell Lines

   • Barbara Gomez
   • Jing Zhu
   • William B. Thornhill

   Original Paper 05 January 2017 Pages: 25 - 33

   

5. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs

   • Patrick Appiah-Kubi
   • Mahmoud Soliman

   Original Paper 02 December 2016 Pages: 35 - 48

   

6. Identification of Binding Mode and Prospective Structural Features of Novel Nef Protein Inhibitors as Potential Anti-HIV Drugs

   • Suri Moonsamy
   • Soumendranath Bhakat
   • Mahmoud E. S. Soliman

   Original Paper 16 December 2016 Pages: 49 - 64

   

7. VP40 of the Ebola Virus as a Target for EboV Therapy: Comprehensive Conformational and Inhibitor Binding Landscape from Accelerated Molecular Dynamics

   • Marissa Balmith
   • Mahmoud E.S. Soliman

   Original Paper 01 February 2017 Pages: 65 - 78

   

8. Role of the Helix in Talin F3 Domain (F3 Helix) in Talin-Mediated Integrin Activation

   • Ang Li
   • Qiang Guo
   • Weiming Hu

   Original Paper 18 January 2017 Pages: 79 - 86

   

9. Maturation of Adipocytes is Suppressed by Fluid Shear Stress

   • Jongyun Choi
   • Sei Young Lee
   • Chi Hyun Kim

   Original Paper 09 November 2016 Pages: 87 - 94

   

10. Nano-Mechanical Characterization of Ataxia Telangiectasia Cells Treated with Dexamethasone

    • Michele Menotta
    • Sara Biagiotti
    • Mauro Magnani

    Original Paper 08 December 2016 Pages: 95 - 102

    

11. Effects of Electroporation on Tamoxifen Delivery in Estrogen Receptor Positive (ER+) Human Breast Carcinoma Cells

    • Meric Arda Esmekaya
    • Handan Kayhan
    • Ayse G. Canseven

    Original Paper 16 December 2016 Pages: 103 - 109

    

12. N-Terminal pro-B-Type Natriuretic Peptide Levels are Linked with Modified Child-Pugh Classification in Patients with Nonalcoholic Cirrhosis [NT-ProBNP and Liver Cirrhosis]

    • Abdulbaki Kumbasar
    • Mehtap Navdar
    • Ozgur Tanriverdi

    Original Paper 02 December 2016 Pages: 111 - 117

13. Site-Specific Acetyl Lysine Antibodies Reveal Differential Regulation of Histone Acetylation upon Kinase Inhibition

    • Shi Chen
    • Suping Chen
    • Guoqiang Xu

    Original Paper 19 December 2016 Pages: 119 - 129

    

14. Metabolic Transition of Milk Lactose Synthesis and Up-regulation by AKT1 in Sows from Late Pregnancy to Lactation

    • Fang Chen
    • Baoliang Chen
    • Yinzhi Zhang

    Original Paper 26 December 2016 Pages: 131 - 138

    

15. IP-10/CXCR3 Axis Promotes the Proliferation of Vascular Smooth Muscle Cells through ERK1/2/CREB Signaling Pathway

    • Hui-jin Wang
    • Yu Zhou
    • Zuo-jun Hu

    Original Paper 23 January 2017 Pages: 139 - 147