Editor’s commentary: Introduction to the first issue Jaffer A. Ajani Editor’s Commentary Pages: 1 - 1
Second-line therapy for advanced colorectal cancer Geoff ChongDavid Cunningham OriginalPaper Pages: 7 - 12
New developments in therapy for metastatic colorectal cancer Sharlene Gill OriginalPaper Pages: 13 - 17
Using biologic markers to optimize therapies Wendy L. AllenPatrick G. Johnston OriginalPaper Pages: 18 - 23
Optimizing adjuvant therapy for colon cancer: Ongoing investigations Hanna KellyBert H. O’NeilRichard M. Goldberg OriginalPaper Pages: 27 - 33
Chemotherapy in patients with resectable liver metastases from colorectal cancer Mohamed Hebbar OriginalPaper Pages: 34 - 40
Advances in surgical technique for primary rectal cancer Scott E. RegenbogenJames C. Cusack Jr OriginalPaper Pages: 43 - 50
Chemoradiation for localized rectal cancer: Neoadjuvant versus adjuvant approaches Lawrence S. Blaszkowsky OriginalPaper Pages: 51 - 57
The integration of biologic agents into the current systemic management of rectal cancer David P. Ryan OriginalPaper Pages: 58 - 62