1. De novo transcriptome assembly and characterization of nine tissues of Lonicera japonica to identify potential candidate genes involved in chlorogenic acid, luteolosides, and secoiridoid biosynthesis pathways

   • Amit Rai
   • Hidetaka Kamochi
   • Mami Yamazaki

   Original Paper Open access 14 September 2016 Pages: 1 - 15

   

2. Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives

   • Megan M. Marlow
   • Sumedh S. Shah
   • Regina M. Graham

   Review 02 July 2016 Pages: 16 - 26

   

3. Glycyrrhetinic acid protects H9c2 cells from oxygen glucose deprivation-induced injury through the PI3K/AKt signaling pathway

   • Liqin Wang
   • Yuyan Zhang
   • Jiehong Yang

   Original Paper 12 July 2016 Pages: 27 - 35

   

4. AU-1 from Agavaceae plants causes transient increase in p21/Cip1 expression in renal adenocarcinoma ACHN cells in an miR-34-dependent manner

   • Tomofumi Fujino
   • Akihito Yokosuka
   • Makio Hayakawa

   Original Paper 07 July 2016 Pages: 36 - 43

   

5. Marine spongean polybrominated diphenyl ethers, selective growth inhibitors against the cancer cells adapted to glucose starvation, inhibits mitochondrial complex II

   • Masayoshi Arai
   • Dayoung Shin
   • Motomasa Kobayashi

   Original Paper 23 July 2016 Pages: 44 - 49

   

6. Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins

   • Nhu Ngoc Quynh Vo
   • Ery Odette Fukushima
   • Toshiya Muranaka

   Original Paper 04 August 2016 Pages: 50 - 58

   

7. Efficacy of Kaempferia parviflora in a mouse model of obesity-induced dermatopathy

   • Moeko Hidaka
   • Kazumasa Horikawa
   • Yutaka Matsumoto

   Original Paper 03 September 2016 Pages: 59 - 67

   

8. Green tea cultivar ‘Benifuuki’ potentiates split vaccine-induced immunoglobulin A production

   • Yeong-Seon Won
   • Motofumi Kumazoe
   • Hirofumi Tachibana

   Original Paper 03 August 2016 Pages: 68 - 75

   

9. The action and mechanism of myrislignan on A549 cells in vitro and in vivo

   • XinGang Lu
   • Liu Yang
   • Jie Shen

   Original Paper 04 August 2016 Pages: 76 - 85

   

10. Rapid identification of drug-type strains in Cannabis sativa using loop-mediated isothermal amplification assay

    • Masashi Kitamura
    • Masako Aragane
    • Yohei Sasaki

    Original Paper 17 August 2016 Pages: 86 - 95

    

11. Constituents from the leaves of Clausena lansium and their anti-inflammatory activity

    • De-Yang Shen
    • Ping-Chung Kuo
    • Tian-Shung Wu

    Original Paper 18 August 2016 Pages: 96 - 104

    

12. Ephedra Herb extract activates/desensitizes transient receptor potential vanilloid 1 and reduces capsaicin-induced pain

    • Shunsuke Nakamori
    • Jun Takahashi
    • Yoshinori Kobayashi

    Original Paper Open access 08 September 2016 Pages: 105 - 113

    

13. Novel polyacetylene derivatives and their inhibitory activities on acetylcholinesterase obtained from Panax ginseng roots

    • Kazuya Murata
    • Daiki Iida
    • Hideaki Matsuda

    Original Paper 27 August 2016 Pages: 114 - 122

    

14. 5′-AMP-activated protein kinase plays an essential role in geniposide-regulated glucose-stimulated insulin secretion in rat pancreatic INS-1 β cells

    • Yanan Hao
    • Chunyan Liu
    • Jianhui Liu

    Original Paper 07 September 2016 Pages: 123 - 130

    

15. Ginsenosides, ingredients of the root of Panax ginseng, are not substrates but inhibitors of sodium-glucose transporter 1

    • Shengli Gao
    • Hirotaka Kushida
    • Toshiaki Makino

    Original Paper 12 September 2016 Pages: 131 - 138

    

16. Rapid and simple determination of polyphyllin I, II, VI, and VII in different harvest times of cultivated Paris polyphylla Smith var. yunnanensis (Franch.) Hand.-Mazz by UPLC-MS/MS and FT-IR

    • Zhe Wu
    • Ji Zhang
    • Jinyu Zhang

    Original Paper 24 September 2016 Pages: 139 - 147

    

17. Quantitative evaluation and discrimination of wild Paris polyphylla var. yunnanensis (Franch.) Hand.-Mazz from three regions of Yunnan Province using UHPLC–UV–MS and UV spectroscopy couple with partial least squares discriminant analysis

    • Yuangui Yang
    • Hang Jin
    • Yuanzhong Wang

    Original Paper 24 September 2016 Pages: 148 - 157

    

18. Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells

    • Tanyarath Utaipan
    • Anan Athipornchai
    • Warangkana Chunglok

    Original Paper 28 September 2016 Pages: 158 - 169

    

19. Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (V): coumarins and alkaloids from Boenninghausenia japonica and Ruta graveolens

    • Daisuke Nakano
    • Kenji Ishitsuka
    • Junei Kinjo

    Original Paper 13 October 2016 Pages: 170 - 180

    

20. Nobiletin improves emotional and novelty recognition memory but not spatial referential memory

    • Jiyun Kang
    • Jung-Won Shin
    • Sungho Maeng

    Original Paper 09 November 2016 Pages: 181 - 189

    

21. Lignans from guaiac resin decrease nitric oxide production in interleukin 1β-treated hepatocytes

    • Yuki Nakano
    • Masaaki Nasu
    • Yukinobu Ikeya

    Original Paper 05 October 2016 Pages: 190 - 197

    

22. The effects of 18β-glycyrrhetinic acid and glycyrrhizin on intestinal absorption of paeoniflorin using the everted rat gut sac model

    • Rui He
    • Yongsong Xu
    • Muxin Gong

    Original Paper 17 October 2016 Pages: 198 - 207

    

23. Hypocholesterolemic effect of sericin-derived oligopeptides in high-cholesterol fed rats

    • Phakhamon Lapphanichayakool
    • Manote Sutheerawattananonda
    • Nanteetip Limpeanchob

    Original Paper 22 October 2016 Pages: 208 - 215

    

24. Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana

    • Hossam M. Abdallah
    • Hany M. El-Bassossy
    • Zainy M. Banjar

    Original Paper 13 October 2016 Pages: 216 - 226

    

25. Involvement of monoaminergic systems in anxiolytic and antidepressive activities of the standardized extract of Cocos nucifera L.

    • Eliane Brito Cortez Lima
    • Caren Nádia Soares de Sousa
    • Silvânia Maria Mendes Vasconcelos

    Original Paper 21 October 2016 Pages: 227 - 237

    

26. Evaluation of the chemical quality of Sekkoku (石斛) in current Japanese commercial crude drugs: constituents of Flickingeria xantholeuca (Rchb. f.) A.D. Hawkes

    • Mei Muto
    • Haruka Asahina
    • Makio Shibano

    Original Paper 03 November 2016 Pages: 238 - 248

    

27. Aged garlic extract suppresses platelet aggregation by changing the functional property of platelets

    • Naoaki Morihara
    • Atsuko Hino

    Original Paper 20 October 2016 Pages: 249 - 256

    

28. Gastroprotective effect of palmatine against acetic acid-induced gastric ulcers in rats

    • Ling Wang
    • Xue Wang
    • Chun-Su Yuan

    Original Paper 17 November 2016 Pages: 257 - 264

    

29. Evaluation of the safety and efficacy of Glycyrrhiza uralensis root extracts produced using artificial hydroponic and artificial hydroponic-field hybrid cultivation systems

    • H. Akiyama
    • M. Nose
    • K. Yoshimatsu

    Original Paper 15 November 2016 Pages: 265 - 271

    

30. Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds

    • Zahra Tofighi
    • Fahimeh Moradi-Afrapoli
    • Narguess Yassa

    Original Paper 15 November 2016 Pages: 272 - 280

    

31. Two new compounds from Trollius chinensis Bunge

    • Ya Jie-Shi
    • Lin Wei-Sang
    • Guo Gang-Zhang

    Note 15 July 2016 Pages: 281 - 285

    

32. Cannabidiolic acid-mediated selective down-regulation of c-fos in highly aggressive breast cancer MDA-MB-231 cells: possible involvement of its down-regulation in the abrogation of aggressiveness

    • Shuso Takeda
    • Taichi Himeno
    • Hironori Aramaki

    Note 16 August 2016 Pages: 286 - 291

    

33. Constituents from Vitex negundo var. heterophylla and their inhibition of nitric oxide production

    • Chongyue Qiu
    • Liang Tong
    • Lixia Chen

    Note 17 August 2016 Pages: 292 - 298

    

34. Pteleifolols A–E, acetophenone di-C-glycosides and a benzopyran dimer from the leaves of Melicope pteleifolia

    • Ken-ichi Nakashima
    • Naohito Abe
    • Masayoshi Oyama

    Note 06 September 2016 Pages: 299 - 304

    

35. Three new ent-kaurane diterpenes from the herbs of Wedelia prostrata

    • Zhongnan Wu
    • Yubo Zhang
    • Guocai Wang

    Note 07 September 2016 Pages: 305 - 309

    

36. Cytotoxicities of two new isoflavanes from the roots of Dalbergia velutina

    • Sutin Kaennakam
    • Pongpun Siripong
    • Santi Tip-pyang

    Note 07 September 2016 Pages: 310 - 314

    

37. Application of a quantitative ¹H-NMR (¹H-qNMR) method for the determination of geniposidic acid and acteoside in Plantaginis semen

    • Rie Tanaka
    • Risa Inagaki
    • Akito Nagatsu

    Note 08 September 2016 Pages: 315 - 320

    

38. Chodatiionosides A and B: two new megastigmane glycosides from Chorisia chodatii leaves

    • Mamdouh Nabil Samy
    • John Refaat Fahim
    • Mohamed Salah Kamel

    Note 19 October 2016 Pages: 321 - 328

    

39. Hypouricemic effect of flaccidoside II in rodents

    • Guo-bin Zhang
    • Shan-shan Ren
    • Fei-hong Bing

    Note 22 October 2016 Pages: 329 - 333

    

40. Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida

    • Wilmar Maarisit
    • Hiroyuki Yamazaki
    • Michio Namikoshi

    Note 19 November 2016 Pages: 334 - 337