Volume 45, Issue 1

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February 2023

Special Issue: White matter lesions/cognitive decline

Issue Editors:

Farzaneh Sorond,
Anna Csiszar,
Zoltan Ungvari

40 articles in this issue

Topographical differences in white matter hyperintensity burden and cognition in aging, MCI, and AD
Farooq Kamal
Cassandra Morrison
Mahsa Dadar
Original Article 13 October 2022 Pages: 1 - 16
Part of 1 collection:

White matter lesions in age-related cognitive decline: etiology, risk factors, prevention and repair
White matter hyperintensity load varies depending on subjective cognitive decline criteria
Cassandra Morrison
Mahsa Dadar
D. Louis Collins
Original Article 19 November 2022 Pages: 17 - 28
Part of 1 collection:

White matter lesions in age-related cognitive decline: etiology, risk factors, prevention and repair
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial
Lin Yi
Andrea B. Maier
Vidyadhar Kumbhar
Original Article Open access 08 December 2022 Pages: 29 - 43
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake
Michael F. Salvatore
Ella A. Kasanga
Donald K. Ingram
Original Article 30 May 2022 Pages: 45 - 63
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs
Vienna E. Brunt
Akpevweoghene P. Ikoba
Douglas R. Seals
Original Article 27 May 2022 Pages: 65 - 84
Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics
Laura Kananen
Mikko Hurme
Juulia Jylhävä
Original Article Open access 21 July 2022 Pages: 85 - 103
Retrospective reports of socioeconomic disadvantage in childhood and mortality risk: are associations consistent across measures and sex?
Amanda E. Ng
Rodman Turpin
Natalie Slopen
Original Article 30 May 2022 Pages: 105 - 118
Effect of simultaneous exercise and cognitive training on executive functions, baroreflex sensitivity, and pre-frontal cortex oxygenation in healthy older adults: a pilot study
Manon Pellegrini-Laplagne
Olivier Dupuy
Laurent Bosquet
Original Article 26 July 2022 Pages: 119 - 140
The PICLS high-throughput screening method for agents extending cellular longevity identifies 2,5-anhydro-D-mannitol as novel anti-aging compound
Mohammad Alfatah
Frank Eisenhaber
Original Article Open access 15 June 2022 Pages: 141 - 158
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Aging: working memory capacity and spatial strategies in a virtual orientation task
Joaquín Castillo Escamilla
Irene León Estrada
José Manuel Cimadevilla Redondo
Original Article 11 June 2022 Pages: 159 - 175
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Attentional focus effect on dual-task walking in Parkinson’s disease with and without freezing of gait
Yu-An Chen
Ruey-Meei Wu
Cheng-Ya Huang
Original Article 20 June 2022 Pages: 177 - 195
The association between aging-related monocyte transcriptional networks and comorbidity burden: the Multi-Ethnic Study of Atherosclerosis (MESA)
Jingzhong Ding
Kurt Lohman
Yongmei Liu
Original Article 23 June 2022 Pages: 197 - 207
Changes in cAMP signaling are associated with age-related downregulation of spontaneously beating atrial tissue energetic indices
Noa Kirschner Peretz
Sofia Segal
Yael Yaniv
Original Article 05 July 2022 Pages: 209 - 219
Part of 1 collection:

Cell Biology of Vascular Aging
Plant-based diets and risk of frailty in community-dwelling older adults: the Seniors-ENRICA-1 cohort
Javier Maroto-Rodriguez
Mario Delgado-Velandia
Mercedes Sotos-Prieto
Original Article Open access 04 July 2022 Pages: 221 - 232
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Inter- and intra-chromosomal modulators of the APOE ɛ2 and ɛ4 effects on the Alzheimer’s disease risk
Alireza Nazarian
Ian Philipp
Alexander M. Kulminski
Original Article Open access 09 July 2022 Pages: 233 - 247
Aging compromises oligodendrocyte precursor cell maturation and efficient remyelination in the monkey brain
Christina Dimovasili
Ashley E. Fair
Douglas L. Rosene
Original Article 05 August 2022 Pages: 249 - 264
Part of 2 collections:

White matter lesions in age-related cognitive decline: etiology, risk factors, prevention and repair

Animal Models for Translational and Preclinical Geroscience Research
Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata
Pablo Salmón
Caroline Millet
Neal J. Dawson
Original Article Open access 19 August 2022 Pages: 265 - 276
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
Hypothalamic microstructure and function are related to body mass, but not mental or cognitive abilities across the adult lifespan
Melanie Spindler
Christiane M. Thiel
Original Article Open access 27 July 2022 Pages: 277 - 291
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Task-based functional connectivity of the Useful Field of View (UFOV) fMRI task
Jessica N. Kraft
Hanna K. Hausman
Adam J. Woods
Original Article 11 August 2022 Pages: 293 - 309
Part of 1 collection:

Advances in Neurostimulation in Aging: From Basic Science to Clinical Applications
High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity
Brenda Gonzalez
Archana Tare
Yousin Suh
Original Article Open access 10 August 2022 Pages: 311 - 330
Metabolic and molecular responses of human patellar tendon to concentric- and eccentric-type exercise in youth and older age
Hannah Crossland
Matthew S. Brook
Philip J. Atherton
Original Article Open access 11 August 2022 Pages: 331 - 344
Vitamin D₃ promotes longevity in Caenorhabditis elegans
Billy Huggins
Mindy Farris
Original Article 24 August 2022 Pages: 345 - 358
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Lipidomics profiling of biological aging in American Indians: the Strong Heart Family Study
Pooja Subedi
Helena Palma-Gudiel
Jinying Zhao
Original Article 11 August 2022 Pages: 359 - 369
Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT₄R) in the postmortem brains of individuals without cognitive impairment
Caglar Cosarderelioglu
Lolita S. Nidadavolu
Peter M. Abadir
Original Article 15 August 2022 Pages: 371 - 384
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice
Jessica M. Snyder
Kerriann M. Casey
Warren Ladiges
Original Article Open access 16 August 2022 Pages: 385 - 397
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile
Mary Revelas
Anbupalam Thalamuthu
Karen A. Mather
Original Article Open access 16 August 2022 Pages: 399 - 413
A metabolomic signature of the APOE2 allele
Paola Sebastiani
Zeyuan Song
Thomas T. Perls
Original Article 23 August 2022 Pages: 415 - 426
Cathepsin F is a potential marker for senescent human skin fibroblasts and keratinocytes associated with skin aging
Kento Takaya
Toru Asou
Kazuo Kishi
Original Article Open access 03 September 2022 Pages: 427 - 437
Is an MRI-derived anatomical measure of dementia risk also a measure of brain aging?
Ramon Casanova
Andrea M. Anderson
Stephen B. Kritchevsky
Original Article 02 September 2022 Pages: 439 - 450
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Neither myonuclear accretion nor a myonuclear domain size ceiling is a feature of the attenuated hypertrophic potential of aged human skeletal muscle
Matthew S. Brook
Daniel J. Wilkinson
Philip J. Atherton
OriginalPaper Open access 09 September 2022 Pages: 451 - 462
Part of 1 collection:

Understanding and overcoming the mechanisms driving age-related sarcopenia
The association of measures of body shape and adiposity with incidence of cardiometabolic disease from an ageing perspective
Fleur L. Meulmeester
Ko Willems van Dijk
Raymond Noordam
Original Article Open access 21 September 2022 Pages: 463 - 476
Episodic memory dysfunction and hypersynchrony in brain functional networks in cognitively intact subjects and MCI: a study of 379 individuals
Brenda Chino
Pablo Cuesta
Fernando Maestú
Original Article Open access 15 September 2022 Pages: 477 - 489
Part of 1 collection:

Advances in Neurostimulation in Aging: From Basic Science to Clinical Applications
Bioenergetic and vascular predictors of potential super-ager and cognitive decline trajectories—a UK Biobank Random Forest classification study
Parvin Mohammadiarvejeh
Brandon S. Klinedinst
Auriel A. Willette
Original Article 15 September 2022 Pages: 491 - 505
Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence
Alistaire D. Ruggiero
Matthew A. Davis
Kylie Kavanagh
Original Article 22 September 2022 Pages: 507 - 521
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
A sex-stratified analysis of neuroimmune gene expression signatures in Alzheimer’s disease brains
Cristina Sanfilippo
Paola Castrogiovanni
Michelino Di Rosa
Original Article 22 September 2022 Pages: 523 - 541
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years
Marta Del Pozo-Valero
Marta Corton
Carmen Ayuso
Original Article Open access 03 October 2022 Pages: 543 - 553
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
Age- and time-dependent mitochondrial genotoxic and myopathic effects of beta-guanidinopropionic acid, a creatine analog, on rodent skeletal muscles
Allen Herbst
Judd M. Aiken
Jonathan Wanagat
Original Article 30 September 2022 Pages: 555 - 567
Part of 1 collection:

Understanding and overcoming the mechanisms driving age-related sarcopenia
Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary
Melissa L. Erickson
Jacob M. Allen
Lauren M. Sparks
Original Article Open access 15 October 2022 Pages: 569 - 589
Data-driven health deficit assessment improves a frailty index’s prediction of current cognitive status and future conversion to dementia: results from ADNI
Andreas Engvig
Luigi A. Maglanoc
Alzheimer’s Disease Neuroimaging Initiative
Original Article Open access 19 October 2022 Pages: 591 - 611
Long-term prognostic value of left atrial longitudinal strain in an elderly community-based cohort
Fjolla Zhubi Bakija
Zsolt Bagyura
Béla Merkely
Original Article Open access 09 December 2022 Pages: 613 - 625

Volume 45, Issue 1

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