1. Purine and pyrimidine metabolism: still a black box?

   • G. J. Peters
   • J. H. Beijnen

   Editorial Pages: 37 - 39

2. Clinical and biochemical aspects of uric acid overproduction

   • J. García Puig
   • F. Antón Mateos

   OriginalPaper Pages: 40 - 54

3. Molecular biology of AMP deaminase deficiency

   • Manfred Gross

   OriginalPaper Pages: 55 - 61

4. Release and actions of adenosine in the central nervous system

   • M. J. Higgins
   • H. Hosseinzadeh
   • T. W. Stone

   OriginalPaper Pages: 62 - 68

5. Purine metabolism in the heart

   • Kris Ver Donck

   OriginalPaper Pages: 69 - 76

6. Role of differentiation induction in action of purine antimetabolites

   • George Weber
   • Yuki Hata
   • Noemi Prajda

   OriginalPaper Pages: 77 - 83

7. New targets for pyrimidine antimetabolites in the treatment of solid tumours

   • C. L. van der Wilt
   • G. J. Peters

   OriginalPaper Pages: 84 - 103

8. New targets for pyrimidine antimetabolites for the treatment of solid tumours

   • Veronique W. T. Ruiz van Haperen
   • Godefridus J. Peters

   OriginalPaper Pages: 104 - 112

9. Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives

   • Jan Balzarini

   OriginalPaper Pages: 113 - 126

10. Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review

    • T. Kulikowski

    ReviewPaper Pages: 127 - 138

11. When and how does one search for inborn errors of purine and pyrimidine metabolism?

    • H. A. Simmonds

    OriginalPaper Pages: 139 - 148