Professor Margareta Hammarlund-Udenaes - A Humble Scientist Shaping Modern Neuropharmacokinetics Irena LoryanDavid E. SmithElizabeth C. M. de Lange Editorial 30 June 2022 Pages: 1283 - 1289
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor Stina SyvänenMarkus Fridén Editorial 30 June 2022 Pages: 1291 - 1296
To Measure is to Know: A Perspective on the Work of Dr. Margareta Hammarlund-Udenaes Jessica I. GriffithWilliam F. Elmquist Perspective 15 March 2022 Pages: 1297 - 1301
Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC50 Values in Aging and Alzheimer’s Disease, Using the Physiologically Based LeiCNS-PK3.0 Model Mohammed A. A. SalehJulia S. BloembergElizabeth C. M. de Lange Research Paper Open access 23 May 2022 Pages: 1303 - 1319
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development Irena LoryanAndreas ReichelMarkus Fridén Research Paper Open access 11 April 2022 Pages: 1321 - 1341
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology Makoto HirasawaMohammed A. A. SalehElizabeth C. M. de Lange Research Paper Open access 07 March 2022 Pages: 1343 - 1361
Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery Kristiina M. HuttunenTetsuya TerasakiYasuo Uchida Expert Review Open access 07 March 2022 Pages: 1363 - 1392
Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs Hina TakeuchiMasayoshi SuzukiYasuo Uchida Research Paper. 29 April 2022 Pages: 1393 - 1413
Targeting Transporters for Drug Delivery to the Brain: Can We Do Better? Elena PurisGert FrickerMikko Gynther Expert Review Open access 31 March 2022 Pages: 1415 - 1455
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo Krzysztof KucharzNikolay KutuzovMartin Lauritzen Expert Review 16 May 2022 Pages: 1457 - 1468
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy Austin SunJoanne Wang Research Paper 11 April 2022 Pages: 1469 - 1480
PET Imaging in Preclinical Anti-Aβ Drug Development Stina SyvänenSilvio R. MeierDag Sehlin Expert Review Open access 02 May 2022 Pages: 1481 - 1496
Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer’s Disease in Rat and Dog Etienne LessardKerry RennieBalu Chakravarthy Research Paper Open access 15 June 2022 Pages: 1497 - 1507
Transferrin Receptor Binding BBB-Shuttle Facilitates Brain Delivery of Anti-Aβ-Affibodies Rebecca FaresjöHanna LindbergDag Sehlin Research Paper Open access 10 May 2022 Pages: 1509 - 1521
Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier Zhou YeBenjamin D. GastfriendEric V. Shusta Research Paper 15 February 2022 Pages: 1523 - 1534
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells Toshiki KurosawaDaiki SakoYoshiharu Deguchi Research Paper Open access 11 April 2022 Pages: 1535 - 1547
Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening Moeno KadoguchiHiroshi ArakawaIkumi Tamai Research Paper 21 March 2022 Pages: 1549 - 1559
Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood–Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells Hinako NaganoShingo ItoSumio Ohtsuki Research Paper 22 November 2021 Pages: 1561 - 1574
In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans Ryo ItoHanae MorioTomomi Furihata Research Paper 14 March 2022 Pages: 1575 - 1586
In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals Saeideh NozohouriShiva Hadi EsfahaniThomas J. Abbruscato Research Paper 03 March 2022 Pages: 1587 - 1598
High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3 Eugene C. ChenPär MatssonKathleen M. Giacomini Research Paper Open access 28 January 2022 Pages: 1599 - 1613
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species David A. TessSangwoo RyuLi Di Research Paper 07 March 2022 Pages: 1615 - 1632
Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations Kristina Öbrink-HansenAnh Duc PhamMaiken Stilling Research Paper 01 March 2022 Pages: 1633 - 1643
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers Arimi FujitaSaki NoguchiMasatoshi Tomi Research Paper Open access 26 January 2022 Pages: 1645 - 1658
Correction: In Vitro—In Vivo Extrapolation of Hepatic Clearance in Preclinical Species David A. TessSangwoo RyuLi Di Correction 21 March 2022 Pages: 1659 - 1659
Correction to: Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells Toshiki KurosawaDaiki SakoYoshiharu Deguchi Correction Open access 20 April 2022 Pages: 1661 - 1661