Enhancing Molecular Promiscuity Evaluation Through Assay Profiles Sorin AvramRamona CurpanLiliana Halip Research Paper 18 October 2018 Article: 240
Progress in Inherited Retinal Disease Drug Discovery and Development: A Foundation’s Perspective Benjamin Yerxa Perspective Open access 18 October 2018 Article: 239
Identification of D-Amino Acids in Light Exposed mAb Formulations Rupesh BommanaNatalia SubelzuChristian Schöneich Research Paper 17 October 2018 Article: 238
Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product Liem Andhyk HalimMaripaz MárquezHuub Schellekens Research Paper Open access 02 October 2018 Article: 226
Population Pharmacokinetics and Exposure-Response Relationships of Naldemedine Ryuji KubotaKazuya FukumuraToshihiro Wajima Research Paper Open access 02 October 2018 Article: 225
Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN1 Yusuke MasuoYuri OhbaYukio Kato Research Paper 02 October 2018 Article: 224
A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics Taro ShimizuAmr S. Abu LilaTatsuhiro Ishida Research Paper 02 October 2018 Article: 223
Mitigation of Oxidation in Therapeutic Antibody Formulations: a Biochemical Efficacy and Safety Evaluation of N-Acetyl-Tryptophan and L-Methionine Michelle Z. DionDanielle LeiskeCleo M. Salisbury Research Paper 02 October 2018 Article: 222
Nasal Administration of Cationic Nanoemulsions as Nucleic Acids Delivery Systems Aiming at Mucopolysaccharidosis Type I Gene Therapy Roselena Silvestri SchuhJuliana BidoneHelder Ferreira Teixeira Research Paper 26 September 2018 Article: 221
Probing Conformational Diversity of Fc Domains in Aggregation-Prone Monoclonal Antibodies Subhabrata MajumderMichael T. JonesArun Alphonse Ignatius Research Paper 25 September 2018 Article: 220
Fragmentation of a Monoclonal Antibody by Peroxotungstate Hasitha RathnayakaOlivier MozziconacciChristian Schöneich Research Paper 25 September 2018 Article: 219
Synthetically Lethal BMN 673 (Talazoparib) Loaded Solid Lipid Nanoparticles for BRCA1 Mutant Triple Negative Breast Cancer Gamze Guney EskilerGulsah CecenerBerrin Tunca Research Paper 25 September 2018 Article: 218
Targeted Ocular Drug Delivery with Pharmacokinetic/Pharmacodynamic Considerations Jie ShenGuang Wei LuPatrick Hughes Research Paper 25 September 2018 Article: 217
Population Pharmacokinetic Modelling for Estimation of Remifentanil Metabolic-Ratio Using Non-steady-State Concentrations under Rapidly Adaptive Dosing Monica SimeoniChao Chen Research Paper 25 September 2018 Article: 216
CFD Supported Investigation of Shear Induced by Bottom-Mounted Magnetic Stirrer in Monoclonal Antibody Formulation Tobias LadnerSebastian OdenwaldJulien Bœuf Research Paper 25 September 2018 Article: 215
Intra-Vial Heterogeneity in Physical Form of Mannitol in Colyophilized Binary Systems S. ThakralS. KoranneR. Suryanarayanan Research Paper 21 September 2018 Article: 214
Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead Estefania GrotzNancy TateosianMarcela A. Moretton Expert Review 20 September 2018 Article: 213
Correction to: Preclinical Development of Cell-Based Products: a European Regulatory Science Perspective James W. McBlaneParvinder PhulMichaela Sharpe Correction Open access 20 September 2018 Article: 212
Genetic Basis of Delayed Hypersensitivity Reactions to Drugs in Jewish and Arab Populations Mohammed AboukaoudShoshana IsraelSara Eyal Expert Review 17 September 2018 Article: 211
Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds Kasiram KatneniThao PhamSusan A. Charman Research Paper Open access 17 September 2018 Article: 210
Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory Elisa A. M. CalvierThu Thuy NguyenCatherijne A. J. Knibbe Research Paper Open access 14 September 2018 Article: 209
Drug-Polymer Interaction, Pharmacokinetics and Antitumor Effect of PEG-PLA/Taxane Derivative TM-2 Micelles for Intravenous Drug Delivery Qiao WangYi LiuXing Tang Research Paper 13 September 2018 Article: 208
Cationic Liposomes: A Flexible Vaccine Delivery System for Physicochemically Diverse Antigenic Peptides Jeroen HeutsEleni Maria VarypatakiWim Jiskoot Research Paper Open access 12 September 2018 Article: 207
pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells Francesca SacchettiGaetano MarvertiEliana Leo Research Paper 12 September 2018 Article: 206
Molecular Targets of the Hydrophobic Block of Pluronics in Cells: a Photo Affinity Labelling Approach A. ZhirnovE. NamI. Grozdova Research Paper 06 September 2018 Article: 205
Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity Dong GuoHong YangYan Shu Research Paper 06 September 2018 Article: 204
Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats Dawei SongDebra C. DuBoisWilliam J. Jusko Research Paper 06 September 2018 Article: 203
Correction to: Bioreducible Poly(Amino Ethers) Based mTOR siRNA Delivery for Lung Cancer Nishant S. GandhiSudhakar GodeshalaMahavir B. Chougule Correction 05 September 2018 Article: 202
Co-Delivery of Teriflunomide and Methotrexate from Hydroxyapatite Nanoparticles for the Treatment of Rheumatoid Arthritis: In Vitro Characterization, Pharmacodynamic and Biochemical Investigations Shweta PandeyVijay KumarSushama Talegaonkar Research Paper 05 September 2018 Article: 201
Radiolabeled PLGA Nanoparticles for Effective Targeting of Bendamustine in Tumor Bearing Mice Iliyas KhanAvinash GothwalUmesh Gupta Research Paper 31 August 2018 Article: 200
Fabrication of TPGS-Stabilized Liposome-PLGA Hybrid Nanoparticle Via a New Modified Nanoprecipitation Approach: In Vitro and In Vivo Evaluation Mengyuan ZhangJianhua HeJianping Liu Research Paper 30 August 2018 Article: 199