1. The Science of USP 1 and 2 Dissolution: Present Challenges and Future Relevance

   • Vivian Gray
   • Gregg Kelly
   • Stephen Mayock

   Expert Review 23 January 2009 Pages: 1289 - 1302

2. Immunological Risk of Injectable Drug Delivery Systems

   • Wim Jiskoot
   • Rianne M. F. van Schie
   • Huub Schellekens

   Expert Review Open access 27 February 2009 Pages: 1303 - 1314

   

3. Properties Influencing the Relative Binding Affinity of Pteroate Derivatives and Drug Conjugates Thereof to the Folate Receptor

   • Christopher P. Leamon
   • Fei You
   • Iontcho R. Vlahov

   Research Paper 03 February 2009 Pages: 1315 - 1323

   

4. Biodegradable Nanoparticles Improve Oral Bioavailability of Amphotericin B and Show Reduced Nephrotoxicity Compared to Intravenous Fungizone®

   • J. L. Italia
   • M. M. Yahya
   • M. N. V. Ravi Kumar

   Research Paper 13 February 2009 Pages: 1324 - 1331

   

5. Accurate Potentiometric Determination of Lipid Membrane–Water Partition Coefficients and Apparent Dissociation Constants of Ionizable Drugs: Electrostatic Corrections

   • Mustafa M. A. Elsayed
   • Ulrich Vierl
   • Gregor Cevc

   Research Paper 13 March 2009 Pages: 1332 - 1343

   

6. Reservoir Based Fentanyl Transdermal Drug Delivery Systems: Effect of Patch Age on Drug Release and Skin Permeation

   • Suneela Prodduturi
   • Glen J. Smith
   • Lucinda Buhse

   Research Paper 20 February 2009 Pages: 1344 - 1352

   

7. Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration

   • Niels Hagenaars
   • Enrico Mastrobattista
   • Wim Jiskoot

   Research Paper 18 February 2009 Pages: 1353 - 1364

   

8. Manufacturing Nanosized Fenofibrate by Salt Assisted Milling

   • Vadym N. Mochalin
   • Adarsh Sagar
   • Yury Gogotsi

   Research Paper 18 February 2009 Pages: 1365 - 1370

   

9. Microspheres with Ultrahigh Holmium Content for Radioablation of Malignancies

   • W. Bult
   • P. R. Seevinck
   • J. F. W. Nijsen

   Research Paper Open access 25 February 2009 Pages: 1371 - 1378

   

10. The Role of Corneocytes in Skin Transport Revised—A Combined Computational and Experimental Approach

    • Steffi Hansen
    • Arne Naegel
    • Ulrich F. Schaefer

    Research Paper 25 February 2009 Pages: 1379 - 1397

    

11. A Novel Hydrophilic Adhesive Matrix with Self-Enhancement for Drug Percutaneous Permeation Through Rat Skin

    • Jianhua Zhang
    • Zhipeng Liu
    • Anjie Dong

    Research Paper 19 February 2009 Pages: 1398 - 1406

    

12. Targetable HPMA Copolymer–Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

    • Mark P. Borgman
    • Abhijit Ray
    • Hamidreza Ghandehari

    Research Paper 19 February 2009 Pages: 1407 - 1418

    

13. Utility of Hydroxypropylmethylcellulose Acetate Succinate (HPMCAS) for Initiation and Maintenance of Drug Supersaturation in the GI Milieu

    • William Curatolo
    • James A. Nightingale
    • Scott M. Herbig

    Research Paper 10 March 2009 Pages: 1419 - 1431

    

14. Cell Type-Specific Targeting with Surface-Engineered Lentiviral Vectors Co-displaying OKT3 Antibody and Fusogenic Molecule

    • Haiguang Yang
    • Kye-Il Joo
    • Pin Wang

    Research Paper 04 March 2009 Pages: 1432 - 1445

    

15. Effects of Ionic Strength on Passive and Iontophoretic Transport of Cationic Permeant Across Human Nail

    • Kelly A. Smith
    • Jinsong Hao
    • S. Kevin Li

    Research Paper 07 March 2009 Pages: 1446 - 1455

    

16. Postprandial Changes in Solubilizing Capacity of Human Intestinal Fluids for BCS Class II Drugs

    • Sarah Clarysse
    • Dimitrios Psachoulias
    • Patrick Augustijns

    Research Paper 07 March 2009 Pages: 1456 - 1466

    

17. Involvement of Multidrug Resistance-Associated Protein 1 in Intestinal Toxicity of Methotrexate

    • Sayaka Kato
    • Katsuaki Ito
    • Akira Tsuji

    Research Paper 14 March 2009 Pages: 1467 - 1476

    

18. MF59 Emulsion Is an Effective Delivery System for a Synthetic TLR4 Agonist (E6020)

    • Barbara C. Baudner
    • Vanessa Ronconi
    • Derek T. O’Hagan

    Research Paper 03 March 2009 Pages: 1477 - 1485

    

19. Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism

    • Natalie L. Trevaskis
    • David M. Shackleford
    • Christopher J. H. Porter

    Research Paper 12 March 2009 Pages: 1486 - 1495

    

20. The Impact of Dose and Solubility of Additives on the Release from HPMC Matrix Tablets—Identifying Critical Conditions

    • Farhad Tajarobi
    • Susanna Abrahmsén-Alami
    • Anette Larsson

    Research Paper 12 March 2009 Pages: 1496 - 1503

    

21. A LC-MS/MS Method for the Analysis of Intracellular Nucleoside Triphosphate Levels

    • Ping Chen
    • Zhongfa Liu
    • Kenneth K. Chan

    Research Paper 17 March 2009 Pages: 1504 - 1515

    

22. Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model

    • Xulang Zhang
    • Chee Guan Koh
    • L. James Lee

    Research Paper 17 March 2009 Pages: 1516 - 1524

    

23. Comparing the Relative Oxidative DNA Damage Caused by Various Arsenic Species by Quantifying Urinary Levels of 8-Hydroxy-2′-Deoxyguanosine with Isotope-Dilution Liquid Chromatography/Mass Spectrometry

    • Jin-Zhu Wu
    • Paul C. Ho

    Research Paper 06 March 2009 Pages: 1525 - 1533

    

24. Safety and Robustness of Coated Pellets: Self-Healing Film Properties and Storage Stability

    • Simon Ensslin
    • Klaus Peter Moll
    • Karsten Mäder

    Research Paper 12 March 2009 Pages: 1534 - 1543

    

25. News

    News 22 April 2009 Pages: 1544 - 1545