1. Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications

   • Hermann Koepsell
   • Katrin Lips
   • Christopher Volk

   Expert Review 01 May 2007 Pages: 1227 - 1251

   

2. Dosage Form Development, in Vitro Release Kinetics, and in Vitro–in Vivo Correlation for Leuprolide Released from an Implantable Multi-reservoir Array

   • James H. Prescott
   • Timothy J. Krieger
   • Mark A. Staples

   Research Paper 27 March 2007 Pages: 1252 - 1261

   

3. Expression of the ATP-binding Cassette Membrane Transporter, ABCG2, in Human and Rodent Brain Microvessel Endothelial and Glial Cell Culture Systems

   • Gloria Lee
   • Karlo Babakhanian
   • Reina Bendayan

   Research Paper 23 March 2007 Pages: 1262 - 1274

   

4. Development and Validation of a Physiology-based Model for the Prediction of Oral Absorption in Monkeys

   • Stefan Willmann
   • Andrea N. Edginton
   • Jennifer B. Dressman

   Research Paper 21 March 2007 Pages: 1275 - 1282

   

5. An Oral Adsorbent, AST-120 Protects Against the Progression of Oxidative Stress by Reducing the Accumulation of Indoxyl Sulfate in the Systemic Circulation in Renal Failure

   • Kazuki Shimoishi
   • Makoto Anraku
   • Masaki Otagiri

   Research Paper 27 March 2007 Pages: 1283 - 1289

   

6. Proline Prodrug of Melphalan Targeted to Prolidase, a Prodrug Activating Enzyme Overexpressed in Melanoma

   • Sachin Mittal
   • Xueqin Song
   • Gordon L. Amidon

   Research Paper 22 March 2007 Pages: 1290 - 1298

   

7. Modeling Methadone Pharmacokinetics in Rats in Presence of P-glycoprotein Inhibitor Valspodar

   • Ignacio Ortega
   • Monica Rodriguez
   • Rosario Calvo

   Research Paper 23 March 2007 Pages: 1299 - 1308

   

8. Novel L-Dopa and Dopamine Prodrugs Containing a 2-Phenyl-imidazopyridine Moiety

   • Nunzio Denora
   • Valentino Laquintana
   • Gaetano Liso

   Research Paper 03 April 2007 Pages: 1309 - 1324

   

9. Confocal Microscopy for the Elucidation of Mass Transport Mechanisms Involved in Protein Release from Lipid-based Matrices

   • Stephanie Koennings
   • Joerg Tessmar
   • Achim Göpferich

   Research Paper 25 April 2007 Pages: 1325 - 1335

   

10. Melittin as an Epithelial Permeability Enhancer I: Investigation of Its Mechanism of Action in Caco-2 Monolayers

    • Sam Maher
    • Linda Feighery
    • Siobhán McClean

    Research Paper 21 March 2007 Pages: 1336 - 1345

    

11. Melittin as a Permeability Enhancer II: In Vitro Investigations in Human Mucus Secreting Intestinal Monolayers and Rat Colonic Mucosae

    • Sam Maher
    • Linda Feighery
    • Siobhán McClean

    Research Paper 23 March 2007 Pages: 1346 - 1356

    

12. Theme Section: Transdermal Delivery of Proteins

    • Ajay K. Banga

    Editorial 11 May 2007 Pages: 1357 - 1359

13. Transdermal Delivery of Cytochrome C—A 12.4 kDa Protein—Across Intact Skin by Constant–Current Iontophoresis

    • J. Cázares-Delgadillo
    • A. Naik
    • Y. N. Kalia

    Research Paper 25 April 2007 Pages: 1360 - 1368

    

14. Coating Formulations for Microneedles

    • Harvinder S. Gill
    • Mark R. Prausnitz

    Research Paper 24 March 2007 Pages: 1369 - 1380

    

15. Novel Microneedle Patches for Active Insulin Delivery are Efficient in Maintaining Glycaemic Control: An Initial Comparison with Subcutaneous Administration

    • Lina Nordquist
    • Niclas Roxhed
    • Göran Stemme

    Research Paper 27 March 2007 Pages: 1381 - 1388

    

16. Transdermal Delivery of Interferon Alpha-2B using Microporation and Iontophoresis in Hairless Rats

    • Advait V. Badkar
    • Alan M. Smith
    • Ajay K. Banga

    Research Paper 19 April 2007 Pages: 1389 - 1395

    

17. Ultrasound Mediated Transdermal Insulin Delivery in Pigs Using a Lightweight Transducer

    • E. J. Park
    • Jacob Werner
    • Nadine Barrie Smith

    Research Paper 19 April 2007 Pages: 1396 - 1401

    

18. AAPS Update

    Announcement 19 May 2007 Pages: 1402 - 1403